Sentences with phrase «novel immunomodulatory»
The final aim is improving therapeutic effect and defining rationalized drug combinations with immune checkpoints and proprietary molecules developed by collaborators, including novel immunomodulatory approaches generated at our unit.
https://science.institut-curie.org/
Researchers studying the effects of iPSC - MSCs treatment in an in vivo mouse model discover a novel immunomodulatory mechanism involving caspase proteins
This new study suggests that iPSC - MSC - secreted factors modulate T cell responses by inhibiting the cleavage of caspases, in what represents a novel immunomodulatory mechanism [3].
Not exact matches
The study is investigator led and has therefore focused on clinical need, targeting patients with progressive multiple sclerosis in whom most disability is incurred... The study also reports a predominant effect on neurodegenerative rather than inflammatory outcomes, suggesting a novel mechanism of action that might be suitable as combination treatment with immunomodulatory treatments... Further phase 3 studies to measure the effect of simvastatin on sustained disability, particularly in patients with non-relapsing secondary progressive and primary progressive multiple sclerosis, are clearly needed, but this trial represents a promising point from which to develop trials of progressive disease.»
The lab is developing a novel gene delivery system to produce anti-tumor and immunomodulatory antibodies in vivo for cancer treatment.
L - Glycine: a novel antiinflammatory, immunomodulatory, and cytoprotective agent.