Sentences with phrase «novel laboratory models»

Not exact matches

A team of researchers from the Hyperbaric Biomedical Research Laboratory at the University of South Florida (USF) doubled survival time in an aggressive metastatic cancer model using a novel combination of non-toxic dietary and hyperbaric oxygen therapies.

«This study showed the value of interdisciplinary collaboration through a novel combination of laboratory, observational and modeling work.»

In testing on laboratory mouse models and human MDS / AML samples, the researchers identified a novel substrate of TRAF6 called hnRNPA1, an RNA binding protein.

Through the integration of such large - scale data sets within computational models, his laboratory is unraveling condition - dependent networks of active regulation process and novel principles on the operation of metabolic networks.

The Bergthaler laboratory pursues an integrative approach comprising infection models and tools of immunology, pathology and systems biology in order to dissect novel disease - relevant interactions between pathogens and the host.

Because of the ease with which the CRISPR / Cas9 system can be applied, it has quickly become a robust tool for generating accurate genetic disease models in the laboratory and for identifying novel therapeutic targets in the clinic.

Dr. Jason Yustein's research laboratory is utilizing tissue - specific expression of an oncogenic p53 mutant to form novel, applicable transgenic mouse models of metastatic osteosarcoma and rhabdomyosarcoma, both conditions that have particularly poor patient outcmes.

«Our findings reveal a critical role for telomere length in a mouse model of age - dependent human disease,» said first author Christina Theodoris, an MD / PhD student in the laboratory of Deepak Srivastava, MD. «This model provides a unique opportunity to dissect the mechanisms by which telomeres affect age - dependent disease and also a system to test novel therapeutics for aortic valve disease.»

He has developed laboratory and animal models of the tumor in its microenvironment, which have allowed for both identification of novel targets and validation of novel targeted therapies.