Sentences with phrase «novel markers of»

These databases have also become a crucial link in the identification and development of novel markers of outcome.

«This study opens avenues for the potential use of proteins that control vesicles and regulate autophagy as novel markers of patient survival,» says Soengas.

I received a number of postdoctoral fellowships from the Canadian federal government and health charities, and I pursued a research career until 1995, when my colleagues and I identified a novel marker of HIV infection.

Conclusions: We validated (68) Ga - DOTATATE PET as a novel marker of atherosclerotic inflammation and confirmed that (68) Ga - DOTATATE offers superior coronary imaging, excellent macrophage specificity, and better power to discriminate high - risk versus low - risk coronary lesions than -LSB-(18) F] FDG.

Not exact matches

A detailed understanding of how TSPO binds to such markers opens up novel paths for diagnostic imaging and could constitute an important step along the way to early detection of such diseases and inflammations.

Efforts aimed at finding better drug regimens would therefore greatly benefit from a mouse model with an intrinsic marker that can indicate different stages of pancreatic tumor formation leading to cancer and reflect the effects exerted by novel drug candidates.

Consequently, the use of such a marker suggests a new strategy to screen novel therapeutics in a rapid and efficient manner directly in the tumorigenic mouse.

«Diffusion tensor MR tractography may function as a novel quantitative tool and marker of treatment response,» said study coauthor Jennifer W. Uyeda, MD, Brigham and Women's Hospital.

Kisspeptins circulating in the blood increase dramatically during normal human pregnancy, to several thousand times non-pregnancy levels, which makes them a novel predictive marker for assessing the risk of later complications.

This novel finding is important for our understanding of this complex condition and its development, and warrants further research on the possibility to use the atypical neural response to the own name as a potential biological marker of ASD.

Hence, understanding the interrelationship between genetic markers and use of aspirin and NSAIDs, also known as gene × environment interactions, can help to identify population subgroups defined by genetic background that may preferentially benefit from chemopreventive use of these agents and offer novel insights into underlying mechanisms of carcinogenesis.

«Here we have demonstrated the further use of this novel technology to develop highly sought after biologically relevant fluorescent markers quickly and easily for different imaging needs,» says Caldwell, who led the study.

With the aid of a novel evolutionary platform technology, scientists at the Helmholtz Zentrum München have developed this infrared marker as part of a combined effort to improve the quality of tissue imaging.

Using a novel methodology, the researchers found an association between the disorder and a DNA marker that is very close to the dopamine transporter gene, which controls the intake of this important neural messenger by the nerve cells that respond to dopamine's signal.

Discovery of novel disease - specific and membrane - associated candidate markers in a mouse model of multiple sclerosis.

I will be able to test those common markers in glaucoma, and this study will be a starting point for translating novel imaging techniques, initially developed for cancer detection, to the early detection of glaucoma.

Floryne Buishand, 30, from the Netherlands, is a postdoctoral researcher at the National Cancer Institute / NIH, Bethesda, USA, studies genomic changes associated with endocrine cancers with the ultimate goal of identifying novel diagnostic and prognostic markers, as well as novel therapeutic targets.

Abstract: Background: The Loewenstein - Acevedo Scale for Semantic Interference and Learning (LASSI - L) is a novel cognitive test that measures recovery from proactive semantic interference, which may be an early cognitive marker of Alzheimer's disease (AD).

deCODE is continuing its research on both phenotypes to identify and analyze the roles of these genes, with the aim of finding novel diagnostic markers as well as drug targets that can be used to combat asthma and allergies by going to the underlying causes of both conditions.

His studies have shown that Schlemm's canal (SC) which is central in ocular fluid homeostasis, hence IOP, and thus is directly relevant to glaucoma, has a novel, specialized phenotype with properties that are a blend of blood and lymphatic endothelia based on expression of marker proteins of each lineage.

Researchers continue to find novel ways to explore these biomarkers using ddPCR technology, whether they are epigenetic markers to determine cancer recurrence after surgery or cell - free DNA (cfDNA) derived from a tumor that reveals the effectiveness of immunotherapy.

Background: The Loewenstein - Acevedo Scale for Semantic Interference and Learning (LASSI - L) is a novel cognitive test that measures recovery from proactive semantic interference, which may be an early cognitive marker of Alzheimer's disease (AD).

Building on existing clinical research at MD Anderson Cancer Center through collaborations and membership to the RNA Center to create a ncRNA - centric effort to drive discovery of molecular markers of cancer by evaluating, co-developing, facilitating and disseminating novel ncRNA technologies.

By analyzing the molecular aspects of the extensive immune crosstalk between the fungal pathogen and the human host allows to define novel evasion strategies and defines new molecules which can serve as useful markers to develop new antifungal compounds and vaccine candidates.

Abstract: A novel predictive model of sexual orientation using epigenetic markers.

Known and novel independent prognostic markers were identified in our cohort of proteasome inhibitor and IMiD - treated patients with long follow - up, including events with context - specific prognostic value, such as deletions of the PRDM1 gene.

The Second is a work of profound and moving secular spirituality that touches on all the markers of religion, a modern - day American Gothic in which the novel's characters ultimately confront their individual identities through the realization of just how hard it is to make belief believable.

It seems likely (there's even a «Cindy» named in one of the pulp novel quotes), but she is equally indebted to the European photo - novel, and maybe also to Chris Marker's La Jetée.

Capote considered his Tiffany to be the strategic marker of the second phase of his career, in which he refined his prose into a clearer and more subdued form before moving on to his crowning achievement, the visceral non-fiction novel, In Cold Blood.