Sentences with phrase «novel molecular approaches»

In the future, studies are aimed at using novel molecular approaches to selectively delete AMPK in specific brain regions associated with nicotine dependence to better understand the functional role of this protein in addiction.

Not exact matches

In the new study, Bhullar and his colleagues detail a novel approach to finding the molecular mechanism involved in creating the skeleton of the beak.

By using a combination of advanced genetics, molecular approaches, and microscopy techniques, they found that this signaling pathway is used in the adult brain in a completely novel way.

Moreover, these DNA nanostructures provide new applications in molecular medicine, such as novel approaches in tackling cancer.

While various molecular biology techniques were initially used to identify and validate epigenetics enzymes and their substrates, novel approaches are now available to perform pharmacological characterization of histone - modifying enzymes.

«New imaging technique able to watch molecular dynamics of neurodegenerative diseases: Novel imaging approach could improve molecular - scale understanding of early disease stages.»

«These studies identify telomeres as a new molecular route implicated in the origin of liver diseases such as cirrhosis, hepatitis or liver cancer, as well as novel therapeutic approaches to prevent and combat them,» concluded the researchers.

These images confirm that this approach to direct the placement of nanoparticles on DNA - encoded vertices of molecular frames could be a successful strategy for fabricating novel nanomaterials.

Dr. Qimin Zhan, Principal Investigator of this project and the Director of State Key Laboratory of Molecular Oncology, Chinese Academy of Medical Sciences Cancer Hospital, said, «For sure, the findings of this project provide novel insights into understanding of underlying mechanism for this malignant ESCC, and enable us to explore potential diagnostic biomarkers and drug targets, and to develop useful clinical therapeutic approaches.

Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report preliminary success testing an entirely novel approach — tagging bacteria with a molecular «homing beacon» that attracts pre-existing antibodies to attack the pathogens.

Using a combination of molecular biology, biochemical and novel multi-dimensional digital imaging approaches we study in real - time complex multi dimensional signal integration during the interaction of T cells with live antigen - presenting cells.

We aim to identify molecular, circuit, and network mechanisms of cognitive dysfunction and to develop novel therapeutic approaches to restore brain functions in AD and related disorders.

Our teams develop novel approaches as well as utilize routine routes to synthesize molecular, nanostructured, and solid - state systems; analyze the samples with multiple instruments; and model the results for detailed insight and to predict new systems for synthesis and analysis.

The resulting data are being combined in a systems biology approach with high - resolution clinical phenotyping and findings obtained with a large array of established and novel in vitro, ex vivo and in vivo disease models to identify disease - associated genetic variants, disease - defining molecular signatures, and potential targets for therapeutic intervention.

Mathematician Dr John MacKenzie and molecular biologist Professor Robert Insall have teamed up to take a novel approach to understanding cell migration.

The HFSP supports novel, innovative and interdisciplinary basic research focused on the complex mechanisms of living organisms; topics range from molecular and cellular approaches to systems and cognitive neuroscience and the interactions between organisms.

The molecular mechanisms of life history alterations in a rotifer: a novel approach in population dynamics.

Here, I discuss a novel computational approach for the detection of allostery in protein complexes by way of molecular dynamics simulation and advanced data reduction protocols.

Because molecular manufacturing cuts across a number of fields — physics, chemistry, mechanical engineering, software, and more — and because it uses a rather novel approach to building stuff, almost any scientist will find something in the proposal that violates one or more intuitions.

Omics are novel, comprehensive approaches for analysis of complete genetic or molecular profiles of humans and other organisms.

The organoids are unique to each patient's tumor and could offer a novel approach to studying the molecular mechanisms associated with resistance to cancer - fighting drugs.

Ward et al. highlight results from molecular and preclinical studies, discuss clinical trial results to date, describe ongoing investigations, and assess novel approaches for the enhancement of MSC based cardiac regeneration, such as genetic modification.

They are developing novel computational approaches that combine molecular interaction and pathway information with «omics data to develop clinically predictive models and identify therapeutically targetable pathways.

These tumor suppressor genes are two of the most frequently altered genes in human cancer, and understanding how they function at the molecular level will both refine our fundamental understanding of this disease and suggest novel therapeutic approaches to treat it.

There her research focused on inventing molecular, bead and array - based approaches to enable novel vaccine discovery against infectious and chronic diseases At the University of Texas Southwestern Medical she pursued technologies that became the basis of a Texas biotechnology company that was ultimately acquired by MacroGenics, Inc..

Here, we investigate the hypothesis that miR - 181a regulates the molecular pathways that control mDA axonal growth, and provide evidence that miR - 181a inhibition may be a novel therapeutic approach for axonal regeneration in PD.

72/3: 45 Systems genetics approach unravels the molecular mechanisms underlying lung function variation and uncovers novel therapeutic targets for COPD.

Clinical and Regenerative medicine refers to development and implementation of advanced therapeutic approaches that may involve the support of expertise in gene / cell therapy, tissue engineering, pharmacology and pharmacogenomics, development of novel molecular target therapy.