Not exact matches
Using complex mathematical algorithms, this
novel antenna transmits a unique
signal to every phone, giving everyone a personal
network.
A related study, also published in PLOS Genetics, shows that RPM - 1 functions as a part of a
novel pathway to control β - catenin activity — this is the first evidence that RPM - 1 works in connection with extracellular
signals, such as a family of protein growth factors known as Wnts, and is part of larger
signaling networks that regulate development.
Along with other research in this area, Schreiber's HDAC discovery and his
novel «
signaling network model» of chromatin revealed the genetic complex to be not just a simple structural element, but one with a key regulatory function that is central to epigenetics.
We study genetic
networks that distinguish stem cells from their differentiating descendants as well as the role of mobile small RNAs as
novel meristem - derived
signals that pattern leaves
The consortium will • design and test
novel body sensor
network for biofeedback restitution • design and test new algorithms and
signal processing • implement biofeedback multi-sensory restitution channels and methods
To understand the selection mechanism behind mutations,
network - based studies were used to estimate the importance of a mutated protein compared to non-mutated ones in
signalling and protein — protein interaction
networks.10, 11,12,13 Proteins mutated in cancer were found having a high number of interacting partners (i.e., a high degree of connectivity), which indicates high local importance.10 Mutated proteins are also often found in the centre of the
network, in key global positions, as quantified by the number of shortest paths passing through them if all proteins are connected with each other (i.e., they have high betweenness centrality; hereafter called betweenness).11, 12 Mutated proteins also have high clustering coefficients, which means their neighbours are also neighbours of each other.10, 13 Moreover, neighbourhood analysis of mutated proteins have been previously successfully used to predict
novel cancer - related genes.14, 15 However, to the best of our knowledge, no study has concentrated particularly on the topological importance of first neighbours of mutated proteins in cancer, and their usefulness as drug targets themselves.