Sentences with phrase «novel therapeutic intervention»
A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis.
http://www.nature.com/
Nevertheless, this is an exciting finding and one that holds promise as the basis for a novel therapeutic intervention.
The study provides a direct connection between bile acids and fat loss and envisions novel therapeutic intervention in obese people.
As such, novel therapeutic interventions are needed to protect the heart from injury and improve clinical outcomes in this patient group,» Hausenloy said.
His research aims to determine the underlying biochemistry and molecular mechanisms of these diseases, then develop and test novel therapeutic interventions through rigorous translational and clinical trial research.
However, these tumors may display intrinsic or acquired resistance to treatment, and classifiers of HER2 - positive tumors are required to improve the prediction of prognosis and to develop novel therapeutic interventions.
The goal of her laboratory is to combine high - resolution computational reconstructions of the microbiome with synthetic biology to devise innovative approaches to create novel therapeutic interventions and investigate the underlying ecology of skin microbial communities.
Oberman's research interest lies in using electrophysiological techniques (such as EEG and TMS and TCS) to investigate neural circuits whose dysfunction may account for the behavioral pathology seen in autism spectrum disorders with the long term goal of developing novel therapeutic interventions.
Not exact matches
«Our study highlights the multifaceted pathophysiology of Dravet Syndrome that includes brain, heart, and autonomic disturbances, and suggests novel therapeutic strategies for interventions to reduce SUDEP in this and perhaps other severe epilepsies,» says David S. Auerbach, Ph.D., of the University of Michigan.
Koo and colleagues are now working on novel therapeutic approaches for targeted interventions, which can be potentially developed for clinical use.
«Identifying a novel mechanism of action is a prerequisite to understanding a disorder, and to development of therapeutic interventions,» Mei said.
Further exploration of the TCA cycle, using metabolomics, may identify novel therapeutic targets for CKD and in turn may help us evaluate the effects of promising interventions.»
This novel and informative work may provide an immunologic explanation for the observed therapeutic efficacy of autologous HSPC transplantation in T1D and pave the way for new therapeutic interventions in the future.
Non-exclusive licenses are available for research and sale of products and services across multiple fields including: research tools, kits, reagents; discovery of novel targets for therapeutic intervention; cell lines for discovery and screening of novel drug candidates; GMP production of healthcare products; production of industrial materials such as enzymes, biofuels and chemicals; and synthetic biology.
More specifically, I identify and examine novel mechanisms governing these factors as potential therapeutic interventions.
The resulting data are being combined in a systems biology approach with high - resolution clinical phenotyping and findings obtained with a large array of established and novel in vitro, ex vivo and in vivo disease models to identify disease - associated genetic variants, disease - defining molecular signatures, and potential targets for therapeutic intervention.
The journal aims to promote novel concepts, programs, technologies, protocols, therapeutic agents, and alternative approaches for the early detection, intervention and treatment of human malignancies and closely associated diseases.
The lab recently developed novel LumiFluor ® optical reporters and are now implementing these reporters for the non-invasive, high resolution in vivo optical imaging of tumor development, progression, and response to therapeutic intervention in genetically engineered mouse models (GEMM) of cancer.
The goal of this research is to help elucidate the neurobiological basis of this disorder and to test novel strategies for therapeutic intervention.
The goal is to produce a comprehensive «encyclopedia «of gene function, that will help identify causative factors of human diseases as well as novel targets for therapeutic intervention.
«Our study also highlights that growth of normal cells and cancer cells is driven by different gene switches, suggesting that further work to find ways to control the activity of such disease - specific switches could lead to novel, highly specific approaches for therapeutic intervention», says Professor Jussi Taipale, who led the study.
Our goal is to identify novel therapeutic targets and participate in both preclinical and clinical studies of new drugs and other interventions.
Distinguishing CFS and nPTLS will have etiologic implications which could lead to novel diagnostics and therapeutic interventions.
Dr. Jason Yustein's research interests include furthering the biological, molecular and genetic understanding of pediatric sarcomas, including osteosarcoma and Ewing's sarcoma, through the formation of novel model systems that will lead to the discovery of new therapeutic targets and subsequent development of new treatment interventions.
Distinguishing nPTLS and CFS permits more focused study of each condition, and can lead to novel diagnostics and therapeutic interventions.
A deeper understanding of these axes provides a new framework for developing novel therapeutic targets and optimising personalised interventions.
Dr. Jung is board certified in veterinary cardiology and in addition to his teaching and clinical responsibilities, investigates mechanisms of heart failure and is developing novel diagnostic and therapeutic interventions.