Sentences with phrase «novel therapies by»
In the future, epigenetic editing could also be used to design novel therapies by initiating permanent changes to cell biology.
https://www.sciencedaily.com/ Not exact matches
And a third, different kind of gene therapy from Spark Therapeutics — to treat a rare inherited form of blindness — is likely to be approved by the end of 2017, too, making this year a landmark for treatments that manipulate the body's own biological mechanisms in novel new ways to fight deadly diseases.
Trapnell and Suzuki were prompted to test the novel macrophage transplantation therapy by studies showing that resident macrophage populations (such as those residing in the lung) can self - maintain without the cells having to regenerate directly from the bone marrow.
PIND's goal is an integrated, interdisciplinary approach to the study of neurodegenerative diseases and their mechanisms, with the aim of transforming cutting - edge science into novel therapies and diagnostics that directly benefit individuals affected by neurodegenerative diseases.
The study authors write that using the LSC17 score to single out high - risk patients predicted to have resistant disease «provides clinicians with a rapid and powerful tool to identify AML patients who are less likely to be cured by standard therapy and who could be enrolled in trials evaluating novel upfront or post-remission strategies.»
«Sepsis: New, novel therapy proposed by researchers.»
Four people with paraplegia are able to voluntarily move previously paralyzed muscles as a result of a novel therapy that involves electrical stimulation of the spinal cord, according to a study funded in part by the National Institutes of Health and the Christopher & Dana Reeve Foundation.
Findings of a three - year clinical trial led by University of Cincinnati (UC) transplant researchers suggest that a novel pre-operative drug therapy reduces antibodies in kidney patients with greater success than with traditional methods, with the potential to increase the patients» candidacy for kidney transplantation and decrease the likelihood of organ rejection.
Coupled with a review of these results by experts on a molecular tumor board, the opportunity exists to identify novel therapies that would target specific abnormalities,» notes senior author of the work, Shridar Ganesan, MD, PhD, associate director for translational science at Rutgers Cancer Institute and associate professor of medicine and pharmacology at Rutgers Robert Wood Johnson Medical School.
Shoemaker has been studying gene therapy as a novel way to treat diseases such as botulism, a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium Clostridium botulinum.
An international team of hematologists including Guy Young, MD, of Children's Hospital Los Angeles, has found that in patients with hemophilia A with inhibitors, a novel therapy called emicizumab, decreases incidence of bleeding episodes by 87 %.
Finally, Pollard wants to close the loop by incorporating code - writing approaches, such as genome editing using CRISPR - based approaches and synthetic biology, which are needed to test and validate hypotheses and could also provide novel therapies.
As demonstrated by the breadth of clinical trial involvement shown above, CCIR members are testing the utility of immune checkpoint blockade in lymphoma (shown by Dr. Allison to be effective against melanoma), genetic engineering in cell therapy (e.g., CD19, CXCR2, TGF - β DNR), and TLR agonists or IL - 2 in vaccine formulations as well as some novel combination therapies, such as the infusion of tumor - reactive lymphocytes from HLA - matched donors who were vaccinated with a lymphoma idiotype.
The work being done by scientists at Longevica may lead to a novel approach in cancer therapy that can significantly improve the efficiency of the current methods of cancer treatment.
«Our goal at QBI is to help make precision medicine a reality by using quantitative research tools to understand the underlying biology behind different disease states, and then to use that knowledge to develop novel diagnostics and therapies and put them into the hands of clinicians,» said Krogan.
A U.S. biotech company will attempt to resurrect 20 brain - dead patients by a combination of novel therapies involving brain stem cells.
CAMBRIDGE, Mass., Nov. 16, 2016 — Proclara Biosciences, a biotechnology company developing novel therapies for diseases caused by protein misfolding, today announced that the U.S. Patent and Trademark Office has issued two new patents related to the company's proprietary General Amyloid Interaction Motif (GAIM) platform.
CAMBRIDGE, Mass., Mar. 1, 2017 — Proclara Biosciences, a biotechnology company developing novel therapies for diseases caused by protein misfolding, today announced that Franz Hefti, Ph.D., president and chief executive officer, will present a company overview at the Cowen and Company 37th Annual Health Care Conference on Wednesday, March 8, 2017 at 1:30 p.m. ET in Boston.
Research physicians will measure the effectiveness of rapid genomic AML screening followed by assignment to novel molecular - targeted and immunologic therapies tailored to a patient's molecular subtype.
Researchers have identified a novel mechanism by which cells die in Alzheimer's disease, which my aid future therapies targeting cell loss in the brain.
Cambridge, MA, September 07, 2016 — Proclara Biosciences, a biotechnology company developing novel therapies for diseases caused by protein misfolding, today announced that it has initiated a Phase 1b clinical trial evaluating NPT088, its lead development candidate for Alzheimer's disease.
Format: Publication Years Covered: 1992 - 2012 Search Strategy: Manually search registries by keywords Project Focus: Two Decades review of the world Special Notes: Found 4749 cell therapy trials total, but only 1058 are «novel» therapy
Graber will also lead the development of the Comparative Models of Regeneration Database (RegenDB), a novel bioinformatics resource supported by the National Institutes of Health (NIH) whose function is to integrate gene function across multiple animal, tissue and cell models in order to validate and inform the hypotheses needed for the discovery and development of regenerative medicine drug therapies.
Additionally, this technology could provide a novel research model by which we transplant cells in vivo to study a disease and its progression from the onset, as well as directly test how effective new therapies are.»
«She will be instrumental in enhancing our ability to develop novel therapies for pediatric diseases by building a framework that translates clinical studies and research findings into daily practices.»
Cellular stress signals sent by macrophages amplify neuroinflammation, provide novel drug targets for MS therapy
Led by Christiana Davis, MD, (in collaboration with Dr. Peter Gabriel, Chief Oncology Informatics Officer and Abigail Doucette, MPH, Research Registry Program Manager), the Thoracic TCE has established project - based databases to track the demographics and response status of patients to immune - oncology treatments, as well as acquired resistance to standard therapies and novel targeted immunotherapies.
SEngine Precision Medicine, instead, is pursuing an innovative approach for the development of novel targets and drugs for cancer therapy by using primary patient organoids initially derived for our diagnostic assay.
By identifying novel molecular targets and potential new drugs, this powerful technological structure will contribute significantly to groundbreaking research towards the development of new anti-cancer therapies.
Interestingly, alterations in these un-druggable genes distinguish cancer cells from normal cells, conferring «synthetic lethal» vulnerabilities that can be exploited by novel targeted therapies.
Although recently approved therapies can increase progression - free survival by a few months, «we think this novel screening system has the potential to uncover new, more effective medications that could be targeted more specifically at a patient's cancer,» Lengyel said.
Professor Satoshi Omura, Honorary Member of the European Academy of Sciences EURASC, received, jointly with Prof. William C. Campbell, the Nobel Prize in Medicine 2015 for their discoveries concerning a novel therapy against infections caused by roundworm parasites.
Access over 20 podcasts recorded by conference keynotes, chair people, session moderators, and speakers who offer their expert perspective and commentary on the scientific trends impacting ADC's, Bioconugates, Novel Therapies, Cell Therapies including Upstream Processing and Downstream Processing, Biosimilars and Formulation strategies for Biologics.
Lovastatin, on the other hand appears to block methane production by these organisms and is being evaluated as a novel microbiome therapy in ongoing clinical trials.»
More interestingly, the effects on infarction size, survival rates and cardiac function can be observed even if the dietary intervention is induced after the ischemic event, by increasing the expression of angiogenic factors and increased vascularization of the damaged myocardium, proposing a novel non-pharmacological therapy for subjects with chronic heart failure (43).
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.
The novel came to me this way — as if told by the various Wongs at a very long family therapy session, only without the therapist, and with license, it...
Her address, «A New Medical Research Model: Advancing Human and Animal Health Humanely,» will detail the concept of a new research model predicated on a meaningful commitment by both medical and veterinary researchers to work cooperatively together to address disease and disorders in humans and animals — evaluating genetic and environmental risk factors, sensitive diagnostic indicators and novel therapies.
Animal Cancer Foundation is a 501 (c)(3) organization dedicated to finding novel treatment therapies and eventual cures for cancer by funding research in and increasing public awareness of comparative oncology, the study of naturally occurring cancers in pets and people to benefit both.
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.
Dr. Hazzah's area of interest is Complementary and Alternative Medicine (CAM) and offers a novel approach to veterinary cancer therapy by combining conventional Western therapies with complementary Eastern therapies to provide a «whole patient» treatment approach.
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.
In the downstairs gallery, a spectacular array of novel ways of living encompasses nature, culture and the human self in the form of a futuristic garden by the London collective Wayward Plants, a practising potter's studio conceived by the American artist Theaster Gates, and Pedro Reyes» Sanatorium, a functioning wellbeing centre where visitors can experience therapies that include hitting a dummy whose face is a balloon on which you have drawn the face of the person you feel most oppressed by.
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.
KEY ACHIEVEMENTS • Saved a patient's life (who was showing signs of stroke) by providing immediate medical assistance in the absence of the head nurse • Devised a novel way of keeping patient specimens from becoming contaminated through implementing safe carriage channels • Introduced the concept of preventative maintenance on medical equipment which decreased breakdowns by 75 % • Rehabilitated a stroke victim who had 85 % paralysis on both sides, by providing dedicated physical therapy support over a period of 4 years
According to a 2009 survey, 76 percent of social workers had used at least one «novel unsupported therapy» — the polite term by which psychotherapy researchers mean «pure bunk.»
Informed by the literature on risk factors for IPV maintenance, drawing from the broader psychopathology and psychotherapy literatures, and guided by third wave behavior therapy models, Dr. Lawrence and her students developed a new conceptual model identifying novel processes that underlie the propensity for violent perpetrators to continue engaging in IPV, applied that model to a novel intervention, and then tested the efficacy and effectiveness of that new intervention.
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.
In addition, we will outline how near - future interventions can be crafted by doing research with novel technologies during relationship therapy.
I always bring the stack of novels and therapy books that have been piling up at home (no e-reader for me yet) and look forward to quiet hours with a chair by the ocean's edge.