Sentences with phrase «novel therapies for»
Her research interests during her residency included novel therapies for the treatment of canine pulmonary hypertension (endothelin) antagonists as well as echocardiographic evaluation of the heart's «pump» function in the setting of mitral valve disease.
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It includes the Rheumatology Clinical Research Unit, which currently is conducting clinical trials of novel therapies for lupus, rheumatoid arthritis, IgG4 - related systemic disease and osteoarthritis.
As the Director of the Early Phase Clinical Trials Program at Roswell Park, I am responsible for developing novel therapies for many types of cancer, including melanoma.
His primary research interest is in novel therapies for myeloma, and he has been at the forefront of the clinical development of bortezomib, lenalidomide, and most recently pomalidomide.
Understanding how TLR ligation leads to complement induction is of utmost interest, as understanding how TLR activation manifests as drusen deposits could allow us to develop novel therapies for the prevention of drusen aggregation.
«She will be instrumental in enhancing our ability to develop novel therapies for pediatric diseases by building a framework that translates clinical studies and research findings into daily practices.»
Having such biomarkers will greatly enhance the development of new and novel therapies for this disabling disorder.»
We are actively forging strategic partnerships to accelerate the development of our novel therapies for patients with protein misfolding diseases.
This «humanized» mouse is susceptible to human liver infections and responds to human drug treatments, providing a new way to test novel therapies for debilitating human liver diseases and other diseases with liver involvement such as malaria.
«Our goal is to build a science - focused company that discovers novel therapies for heart failure patients.»
Cambridge, MA, September 07, 2016 — Proclara Biosciences, a biotechnology company developing novel therapies for diseases caused by protein misfolding, today announced that it has initiated a Phase 1b clinical trial evaluating NPT088, its lead development candidate for Alzheimer's disease.
CAMBRIDGE, Mass., Mar. 1, 2017 — Proclara Biosciences, a biotechnology company developing novel therapies for diseases caused by protein misfolding, today announced that Franz Hefti, Ph.D., president and chief executive officer, will present a company overview at the Cowen and Company 37th Annual Health Care Conference on Wednesday, March 8, 2017 at 1:30 p.m. ET in Boston.
«Dr. Meyers» research is a perfect example as to how fundamental laboratory studies are leading to innovative and novel therapies for breast cancer treatment,» says Dr. Raymond Hohl, director of the Penn State Hershey Cancer Institute.
CAMBRIDGE, Mass., Nov. 16, 2016 — Proclara Biosciences, a biotechnology company developing novel therapies for diseases caused by protein misfolding, today announced that the U.S. Patent and Trademark Office has issued two new patents related to the company's proprietary General Amyloid Interaction Motif (GAIM) platform.
Gladstone was a great fit for me, especially with its background in developmental and translational biology and Bruce's research focus on cutting - edge technologies to model genetic disease and find novel therapies for treating them.
We are currently developing small molecule Nav1.1 activators that increase Nav1.1 currents and interneuron - dependent gamma oscillations in vitro and in vivo to develop novel therapies for conditions with impaired interneuron function, including AD and Dravet syndrome.
If amyloid - beta indeed accumulates to fight a low - grade, persistent infection, it might lead to novel therapies for treating or even preventing Alzheimer's.
His major research interests are human neuroanatomy and neuropathology and the use of animal models to test novel therapies for neurodegenerative diseases including Alzheimer's disease.
In my role as a Clinical Professor of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Professor of Medicine and Director of Early Phase Clinical Trials Program in the Department of Medicine at Roswell Park Comprehensive Cancer Center, I am developing novel therapies for patients with cancer.
Now, a new study suggests the drug may also ease the symptoms of a genetic disease called hereditary hemorrhagic telangiectasia — a discovery that could guide researchers to novel therapies for HHT and other vascular diseases.
As the principal regulator of iron, hepcidin has become a target for researchers developing novel therapies for blood disorders.
While the findings suggest that drugs targeting ASICs may one day lead to novel therapies for anxiety disorders, Braga noted that «more research is needed to understand the roles that ASIC1a channels play in the brain.»
Lindquist was starting a biotech company called FoldRx Pharmaceuticals Inc., which partly relied on Outeiro's findings to develop novel therapies for protein - misfolding diseases.
Attempting to raise funding for their effort to develop a novel therapy for persistent viral infections, the co-founders, who've been best friends since they grew up together in Philadelphia, were on the verge of giving up and heading back to the east coast when Peter Thiel personally persuaded them to stay in town.
The clinical trial results, published online in the Journal of Allergy and Clinical Immunology: In Practice, suggest that Verapamil represents a promising novel therapy for the treatment of CRS with nasal polyps.
Although the findings are promising, Fornai cautions that «it will take some time to establish whether the use of lithium should be considered as a novel therapy for ALS.»
A recent analysis of results from a randomized controlled clinical trial indicates that abaloparatide - SC, a novel therapy for osteoporosis, provides consistent protection against bone fractures in postmenopausal women with...
Calorie restriction in humans is associated with weight loss, reduced inflammation and improved markers for cardiovascular and metabolic health in obese -LCB- Formatting Citation -RCB-(9,10) as well as non-obese (11,12) subjects, proposing a novel therapy for increasing life span.
Not exact matches
And it starts to build novel connections, it's almost like group therapy for memories.
And a third, different kind of gene therapy from Spark Therapeutics — to treat a rare inherited form of blindness — is likely to be approved by the end of 2017, too, making this year a landmark for treatments that manipulate the body's own biological mechanisms in novel new ways to fight deadly diseases.
His work indicates that this cell surface marker could serve as a target for a novel brain cancer vaccine or T - cell therapies engineered to recognize and kill tumors carrying that neoantigen.
On August 30, the U.S. Food and Drug Administration approved a novel gene therapy for patients with a rare type of leukemia.
A spin - off from Queen's University 7 years ago, the drug discovery and development company develops novel cytochrome P450s to generate improved therapies for skin diseases and cancer.
The findings may not only lead to a novel diagnosis tool of PSC, they may also be the starting point for developing microbiota - based therapies.
A novel psychological therapy that encourages addressing emotional experiences related to trauma, conflict and relationship problems has been found helpful for people with the chronic pain condition fibromyalgia.
Thus, mitochondrial rescue agents may be a promising novel strategy for disease - modifying therapy in LRRK2 - related Parkinson's.»
There is therefore pressing need for novel therapies that improve the outcomes.
«Ultimately, understanding the interplay between genetic mutations, gut microbes, and inflammation may lead to novel diagnostics and therapies for intestinal cancer.»
It also provides novel insight into human mesenchymal stem cell - heart cell interactions that can guide future experimental studies to understand the mechanisms underlying mesenchymal stem cell therapy for the heart.
«Researchers identify novel mechanism in combination drug therapy for acute myeloid leukemia, other cancers.»
He hopes that further studies may identify novel approaches to immune - based cancer therapy or reveal new drug targets for inflammatory diseases.
The 2015 Nobel Prize in Physiology or Medicine goes to William C. Campbell and Satoshi Ōmura for their discoveries of a medication against roundworm parasites and to Youyou Tu for her discoveries concerning a novel therapy against malaria.
«We wanted to develop a novel strategy with PET imaging for non-invasively determining EGFR mutation status in real - time, predict NSCLC patients who may benefit from EGFR - TKI therapy, and monitor EGFR - TKI treatment outcome.»
It will open up a novel avenue for curative CML therapy.»
The integrated approaches being developed and used at Moffitt are instrumental for the continued advancement of our understanding of cancer progression and the development of novel cancer therapies.
Little is known, however, about the metabolic pathways that drive the growth of individual glioblastoma subtypes — knowledge that is crucial for developing novel and effective targeted therapies that might improve treatment for these lethal tumors.
Meanwhile, his research teams are moving several other novel therapies toward clinical trials, each of which has potential for use in the synergistic model of cancer treatment that Black believes will offer the best hope for his patients.
«While expanding beta cell mass may still be desirable for future diabetes therapy, improving the local environment of the otherwise healthy aged beta cell could prevent age - associated deterioration in glucose homeostasis and thereby promote healthy ageing, which is conceptually novel and highly exciting,» says Per - Olof Berggren.
Our studies have improved our understanding of the basic biology underlying MMA, created a novel animal model for testing interventions and, now, led us to the promise of a new therapy.»
«We are excited that our translational research team of clinicians and basic researchers have come together to present these novel findings and hope that future studies and trials based on this work can move forward to bring targeted therapies for TED,» commented Dr. Phipps.