Sentences with phrase «novel treatment strategies for»
This work has important implications for developing novel treatment strategies for psychiatric disorders associated with social cognitive deficits, including autism spectrum disorders and schizophrenia.
http://www.emoryhealthsciblog.com/
The study, which is published today in the Journal of Clinical Hypertension and is supported by Barts Charity, devised a novel treatment strategy for 55 patients, involving fractional dosing with tablets (halving or quartering pills), liquid formulations of antihypertensive drugs and patch formulations of antihypertensive drugs — plus use of unlicensed drugs that lower blood pressure.
They integrated university -, government -, and industry - based researchers from the United States and Canada in a combined effort to define the testable prospects of this novel treatment strategy for HIV - AIDS.
Dr. Welsbie's laboratory focuses on the development of neuroprotective agents as a novel treatment strategy for glaucoma.
Should collaborations like these prove to be important also in human breast cancer, disrupting key interactions may be a novel treatment strategy for the disease.
A new study investigates the great potential of adipose - derived cells as a novel treatment strategy for the autoimmune neurodegenerative disease Multiple Sclerosis
«inhibition of the gluconeogenic pathway by citrus flavanones, which was similar to that of the drug metformin, may represent an attractive novel treatment strategy for type 2 diabetes» [8].
Not exact matches
But these findings point us to new strategies and novel compounds that can be developed as treatments that will be more effective for an array of cancer types because they are less susceptible to the emergence of resistance.»
«We wanted to develop a novel strategy with PET imaging for non-invasively determining EGFR mutation status in real - time, predict NSCLC patients who may benefit from EGFR - TKI therapy, and monitor EGFR - TKI treatment outcome.»
«Our approach is likely to «revive» genome - wide association studies as a strategy to identify genetic risk factors and to develop novel treatment options for a wide range of diseases, just as people had hoped for when the genetic code was deciphered a decade ago.»
«These results represent a significant advance in our understanding of how commensal microbes can regulate host intestinal immune responses and suggest that the identification of downstream targets in macrophages and dendritic cells along the GM - CSF axis can help the rationale design of novel strategies for the treatment of IBD patients with defective GM - CSF function,» explained Dr. Merad.
A study led by scientists at The Wistar Institute describes a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA to directly encode protective antibodies against a cancer specific protein.
A gene associated with risk for Alzheimer's disease influences the gut microbiome of mice, potentiating a novel treatment strategy (Ishita Parikh, abstract 476.02, see attached summary).
Fernández warns, «Given the obesity epidemic in the US and worldwide, an increase in those affected by non-alcoholic fatty liver disease is expected in the coming decades and we still do not have a suitable treatment for this condition; A fundamental understanding of this medical problem is therefore essential for development of novel treatment strategies.»
This novel discovery means that scientists can now develop strategies to target these weak spots for treatment of dengue, and possibly other closely related diseases like Zika, influenza and chikungunya.
In conclusion, the results of the present study demonstrate the effect of Hyssopus officinalis L. on chronic asthma, and may provide a novel therapeutic strategy for the treatment of chronic asthma.
Along with our nonprofit partners, this program aims to collect, organize, and validate massive amounts of data generated by clinical trials across our global trial network sites in order to generate novel insights into biomarkers for safety and efficacy, novel treatment strategies, and personalization of treatment regimens.
The screening proposed here is expected to lead to novel strategies for the treatment of centronuclear myopathies by reducing muscle weakness caused by central nuclei in diseased muscles.
One of its priorities is to develop relevant strategies to decipher multiple forms of neuromuscular diseases, identify new therapeutic targets and foster novel strategies for innovative treatments.
Career Goals: Developing of novel immunotherapeutic strategies for the treatment of chronic allergic inflammation and airway remodeling.
This finding reveals unexpected roles for the microbiome and innate immune signalling in the pathogenesis of a cerebrovascular disease, as well as suggesting novel strategies for its treatment.
Kenneth R. Cooke, M.D. University of Michigan Medical School Acute lung injury after SCT: from laboratory insights to novel strategies for diagnosis and treatment
Ann Marie Schmidt, M.D. Columbia University College of Physicians and Surgeons Novel therapeutic strategy for the prevention and treatment of diabetic complications: antagonism of receptor for advanced glycation end products
For patients seeking treatment for a wide range of challenging conditions, Partners HealthCare's wealth of clinical trials offer access to novel therapies or treatment strategies otherwise unavailable in the normal course of caFor patients seeking treatment for a wide range of challenging conditions, Partners HealthCare's wealth of clinical trials offer access to novel therapies or treatment strategies otherwise unavailable in the normal course of cafor a wide range of challenging conditions, Partners HealthCare's wealth of clinical trials offer access to novel therapies or treatment strategies otherwise unavailable in the normal course of care.
The lack of effective strategies for ovarian cancer [1] has led to the development of novel treatment modalities.
The clinical consequences of the molecular results are discussed in Molecular Tumor Boards for novel treatment strategies.
It could lead to novel therapeutic strategies for the treatment of anxiety, psychosis, memory, and mood disorders.
This strategy takes advantage of the cells «somatic memory of origin» and novel reprogramming strategies to make these cells an effective and safe source of cells for the treatment of cartilage defects and osteoarthritis.
In addition, I work closely with colleagues in Lineberger on innovative clinical trials and translational research projects directed at developing novel strategies for the treatment of advanced disease.
Research by Rutgers Cancer Institute of New Jersey finds that targeting a certain signaling pathway with a diabetes drug may be a novel prevention and treatment strategy for pancreatic cancer progression.
The goal of our research is to provide doctors with key, additional information to choose best treatment strategies for breast cancers with novel mutations of unknown significance.
My interests lie in leveraging the information hidden in large - scale omics data for better understanding of the mutational processes causing human cancer, for identifying potential cancer prevention strategies, and for developing novel approaches for targeted cancer treatment.
The main focus of my research program is on design and preclinical evaluation of novel therapeutic strategies for treatment of metastatic cancers, including breast cancer and melanoma.
The endocannabinoid system regulates energy homeostasis through G protein — coupled cannabinoid - 1 receptors5, 6 located in the central nervous system and in various peripheral tissues, including adipose tissue, muscle, the gastrointestinal tract, and the liver.7 While peripheral cannabinoid - 1 receptor activation decreases adiponectin production in adipocytes, 8 central cannabinoid - 1 receptor activation in preclinical studies stimulates eating, decreases muscle, and stimulates hepatic and adipose tissue lipogenic pathways in animal models of obesity.9 In genetic and diet - induced obesity, rimonabant, a selective cannabinoid - 1 receptor blocker, reduces overactivation of the central8, 10 and peripheral11, 12 endocannabinoid system8, 10,13 and prevents weight gain and associated metabolic disorders, thus revealing a novel strategy for the treatment of obesity and related cardiometabolic disorders.
The final conclusion is that progesterone may ``... provide novel therapeutic strategies for the treatment of sleep disturbances, in particular in the elderly.»
Our findings indicate that ApoE4 genotype - induced mitochondrial changes and associated structural damage may explain age - dependent pathology seen in AD, indicating potential for novel treatment strategies in the near future.
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.
The clinicians developed a unique strategy to simultaneously advance a novel cancer treatment for animals and humans.
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.
Tags for this Online Resume: clinical, affairs, scientific, trials, innovative, management, summary, documents, submission, regulatory, 510 (k), ISE, ISS, PK / PD, communicating, monitoring, tactical, strategic, literature, direct, vision, Lead, Director, documentation, resources, execution, consensus, effectiveness, safety, CRA, IVD, medical, device, pharmaceutical, presentation, manuscript, abstract, poster, programs, leadership, career, development, appraisals, optimize, goals, objectives, internal, external, research, investigator, stakeholders, customers, prioritize, product, support, milestones, Microsoft, Word, Excel, statistics, data, analysis, Powerpoint, publication, growth, deliverables, diagnostic, prognostic, treatment, competitive, proven, ability, capable, assess, strategy, feasibility, methodology, design, develop, produce, recommend, recommendation, therapeutic, supervision, review, performance, appraisal, application, indication, company, collaborate, expert, justification, senior, executive, assessment, experienced, marketing, pre-market, pre-IDE, protocol, communication, utility, pharmacology, service, deliver, delivery, drug, metabolism, absorption, excretion, train, training, mentor, mentoring, CRO, reimbursement, XLSTAT, Prism, relationship, contract, consult, consultant, ownership, responsibility, authority, delegate, trends, direction, in - vitro, commercialize, commercialization, approval, clearance, patient, oncology, cancer, metabolic, cardiovascular, kidney, disease, health, outcomes, safe, effective, toxicity, novel, unique, unmet, need, advisors, advisory, committee, IRB, ethical, justified, supportive, care, associate
Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.