Sentences with phrase «novel uses of stem cells»

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«The discovery of the novel progenitor represents a fundamental advance in this field and potentially to the liver regeneration field using cell therapy,» said the study's senior author, Valerie Gouon - Evans, PharmD, PhD, Assistant Professor, in the Department of Developmental and Regenerative Biology, Black Family Stem Cell Institute, at the Icahn School of Medicine at Mount Sicell therapy,» said the study's senior author, Valerie Gouon - Evans, PharmD, PhD, Assistant Professor, in the Department of Developmental and Regenerative Biology, Black Family Stem Cell Institute, at the Icahn School of Medicine at Mount SiCell Institute, at the Icahn School of Medicine at Mount Sinai.

Attrition of novel drug candidates due to cardiovascular liabilities (including proarrhythmic risk due to delayed ventricular repolarization and Torsades - de-Pointes arrhythmia) remains a hurdle for drug discovery efforts, a hurdle which may be mitigated by the use of human induced pluripotent stem - cell derived (hiPSC)- cardiomyocytes.

Novel stem - cell technology developed at Swinburne will be used to grow the massive number of stem cells required for a new hand - held 3 - D printer that will enable surgeons to create patient - specific bone and cartilage.

I - Stem, the Institute for Stem cell Therapy and Exploration of Monogenic Diseases, has signed an agreement with Swissbased healthcare company Roche to use I - Stem's technologies in discovering novel therapies to treat devastating central nervous system (CNS) diseases such as Alzheimer's, schizophrenia, depression and anxiety.

«We have identified novel molecular features in diverse cell types using a new strategy of analyzing hundreds of cells individually,» said Arnold Kriegstein, MD, PhD, director of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at Ucell types using a new strategy of analyzing hundreds of cells individually,» said Arnold Kriegstein, MD, PhD, director of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCell Research at UCSF.

In this Regenerative Medicine commentary, the minutes of the iPSC - FIH trial review committee meetings were examined to identify future lessons for the committees reviewing cutting - edge FIH trials using novel stem cells.

He has developed novel cellular models of neurological diseases (schizophrenia, MS, autism, Alzheimer's, Parkinson's) using human induced pluripotent stem cells (iPSCs) derived from donor patients and differentiated to specific neuronal cell types.

The South Florida Bone Marrow / Stem Cell Transplant Institute is now running a new clinical trial protocol (08001 - BMSCTI) for investigating a novel cancer therapy using transfusions of white blood cells from healthy donors.

The collection of protocols includes the isolation and maintenance of stem cells from various species using «conventional» and novel methods, such as derivation of ES cells from single blastomeres, differentiation of stem cells into specific tissue types, isolation and maintenance of somatic stem cells, stem cell - specific techniques and approaches to tissue engineering using stem cell derivatives.

Using a combination of stem cells and novel analytical tools, scientists at the Wellcome Sanger Institute and their collaborators discovered that clues to the contribution of genetic variation to disease risk lie not only in the genes, but also in the molecular switches that control those genes.

Using a discovery platform whose components range from yeast cells to human stem cells, Whitehead Institute scientists have identified a novel Parkinson's disease drug target and a compound capable of repairing neurons derived from Parkinson's patients.

Although many stem cell therapies are still in their infancy, in the last couple years there have been several important publications on the successful use of novel stem cell treatments in patients.

Dr. Pfaff has developed a novel embryonic - stem cell - based model of SMA that phenocopies the pathology of human SMA, and can be used to study the basis of the disease and screen for compounds that might increase survival of motor neurons.

CAMBRIDGE, Mass. — Using a discovery platform whose components range from yeast cells to human stem cells, Whitehead Institute scientists have identified a novel Parkinson's disease drug target and a compound capable of repairing neurons derived from Parkinson's patients.

His lab has pioneered the generation of clinical grade induced pluripotent stem (iPS) cells using non-viral reprogramming methods such as direct delivery of reprogrammed proteins and novel episomal methods, and has recently identified novel mechanisms underlying metabolic reprogramming during human induced pluripotency.

Researchers using a novel technique find that potential therapeutic worth of mesenchymal stem cells is linked to their motility

His laboratory recently demonstrated a novel use of a specific gene - targeting technique for human embryonic stem cells.

Helmsley expanded support with an additional $ 15 million grant in 2010 to create a collaborative stem cell project involving Salk and Columbia University to fast - track the use of induced pluripotent stem cells to gain new insight into disease mechanisms and screen for novel therapeutic drugs.