Vaccine studies in infants < 6 mo with
novel vaccine candidates have generally demonstrated poor immunogenicity (90).
«Six years ago we began using these samples to identify
novel vaccine candidates and now it's coming full circle.
In addition, we will develop a high through - put PfSEA - 1 specific growth inhibition assay that will guide ongoing immune - epidemiology and ultimately vaccine trials for
this novel vaccine candidate.
Not exact matches
«It's a
novel strategy, and it works beautifully,» said senior investigator Harvey M. Friedman, MD, a professor of Infectious Diseases at Penn. «I know of no other HSV2
vaccine candidate with published results that are as promising as this study.»
Researchers at the University of Maryland and Duke University have designed a
novel protein - sugar
vaccine candidate that, in an animal model, stimulated an immune response against sugars that form a protective shield around HIV.
This has yielded three Tuberculosis
vaccine candidates undergoing phase IIa testing and three first - in - human trials of
novel CMI - inducing adjuvants.
Nanotheraputics for Antibiotic Resistent Emerging Bacterial pathogens (NAREB) European Research Infrastructures for Poverty Related Diseases (EURIPED) Biomarkers for enhanced
vaccines immunosafety (BioVacSafe) European network of
vaccine research and development TRANSVAC Advancing
novel and promising TB
vaccine candidates from discovery to preclinical and early clinical development (TBVAC2020)
The overall aim of this project is to determine the functional significance of antibody targeted cellular and complement responses to a
novel pediatric malaria
vaccine candidate antigen, PfSEA - 1.
discovery of new
vaccine targets by innovative approaches that allow the identification of non-classical
vaccine antigens like non-protein antigens and subdominant epitopes and
novel protein
candidates
By analyzing the molecular aspects of the extensive immune crosstalk between the fungal pathogen and the human host allows to define
novel evasion strategies and defines new molecules which can serve as useful markers to develop new antifungal compounds and
vaccine candidates.
This has yielded three TB
vaccine candidates undergoing phase IIa testing and three first - in - human trials of
novel CMI - inducing adjuvants.
As partner of TRANSVAC, IRTA will provide access to their animal facilities (CReSA) to carry out safety and immunogenicity studies of new
candidate vaccines and / or of
novel vaccination (administration) strategies in pigs, ferrets and other large animal species.
Results from an initial study combining a microbicide
candidate and experimental
vaccine are promising enough to at least keep Imperial College virologist Robin Shattock coming back for more in pursuing what could be a
novel move in preventing HIV infection.
A good knowledge of correlates of protection could predict the efficacy of
novel vaccines at early stages of development and help identify the most promising
candidates for
vaccine trials.
As partner of TRANSVAC2, WBVR will provide access to their animal facilities (Lelystad) to carry out immunogenicity and efficacy studies of new
candidate vaccines and / or of
novel vaccination (administration) strategies in pigs, cattle, ferrets or other animal species.
Research & Development IAVI worked with the Japanese biotech company DNAVEC, based in Tsukuba City, to jointly develop an AIDS
vaccine candidate based on its
novel Sendai vector technology.