Sentences with phrase «now in clinical trials»

MMRF has raised $ 250 million and funded 120 institutions worldwide, has been involved in the development of six new treatments, facilitated more than 50 clinical trials through the consortium, and has 21 MMRF - funded compounds now in clinical trials.

Weinberg uses a similar «hitting the gas» approach to immunotherapy, targeting the T cell co-stimulator OX40 with a drug now in clinical trials.

With enthusiasm for cancer immunotherapy mounting thanks to recent successes in the clinic with immune - based cancer treatments such as anti-CTLA-4 and anti-PD-1 antibodies, and the FDA approvals of sipuleucel - T prostate cancer vaccine and ipilimumab for the treatment of melanoma, and in light of the many promising immunotherapies now in clinical trials with potential for near - term FDA approval, the Cancer Research Institute launched the first annual Cancer Immunotherapy Awareness Month in June 2013 as a way to increase public awareness of the power of immunotherapy to revolutionize cancer treatment and of the need for continued public support for research to bring these treatments to more patients sooner.

PsychoGenics has pioneered the translation of rodent behavioral responses into robust, high throughput, high content phenotyping and its drug discovery platforms, SmartCube ®, NeuroCube ®, and PhenoCube ® have led to shared risk partnerships with major pharma companies such as Sunovion and Roche and resulted in the discovery of several novel compounds now in clinical trials or advanced preclinical development.

Among the 60 compounds, they found one that previously had been used as an antibiotic and is now in clinical trials for Alzheimer's disease.

Antisense approaches, under development for decades and now in clinical trials, shut off the problematic gene.

Engineered bladders are also now in clinical trials.

Members of this new class of antiviral drug are now in clinical trials.

A few other drugs, including a THI derivative and an unrelated drug now in clinical trials for rheumatoid arthritis, also showed beneficial effects in fruit flies.

Auranofin is now in clinical trials for treating chronic lymphocytic leukemia.

Supporters of the programme point out that three candidate drugs developed under the programme, for pathogens including Ebola virus, are now in clinical trials.

«Researchers illuminate key role of NOX proteins in liver disease: Study adds credence to new treatment approach now in clinical trials.»

She says a number of experimental drugs now in clinical trials are designed to target serotonin in other ways in the brain, and may have better success than the SSRIs.

Better memory boosters now in clinical trials should be here in four to five years.

After years of false starts, a new generation of DNA vaccines and medicines for HIV, influenza and other stubborn illnesses is now in clinical trials

Not exact matches

The striking example I focused on then was the cancer drug Avastin, developed by Genentech (now Roche)-- which, at the time, had been studied in at least 400 completed human clinical trials for various cancers.

Participants in United Therapeutics» clinical trials now have their genomes sequenced and researchers at the company plan to correlate patient outcomes with that genomic sequence data.

Apple's ResearchKit platform launched initially in March is now adding a second group of clinical trials.

Speaking of checkpoint inhibitor drugs... Merck's star cancer immunotherapy treatment Keytruda is facing some troubling clinical trial incidents which have now compelled the Food and Drug Administration (FDA) to halt three studies of the drug in multiple myeloma, a rare blood cancer, after a number of patient deaths.

Now a new clinical trial is under way, by New York's Mount Sinai, to test a vaccine to combat recurrence in some of the most deadly forms of cancer, including lung, breast, gynecological and bladder cancers.

Following preliminary clinical trials, the company is now in discussion with a major New York City hospital to integrate Fever Smart into a large clinical research program.

But Novartis, Celgene, and Pfizer are now duking it in the psoriatic arthritis space, unveiling positive clinical trial data for inflammatory drugs Cosentyx, Otezla, and Xeljanz (respectively) during the American College of Rheumatology's (ACR) annual meeting.

Now that the barrier of editing genes in the hospital setting has been broken, these companies and more have pipelines of gene - editing innovation coming to a hospital near you in the next few years, as clinical trials are approved and new ways to cure formerly incurable diseases go mainstream in our lifetimes.

GUMC says its researchers are now planning larger clinical trials with nilotinib for patients with Parkinson's and other similar diseases including Alzheimer's disease, likely to begin in 2016.

The company's lead program, now in phase I clinical trials, is a differentiated PPAR gamma agonist (MIN - 102) that has potential in multiple CNS indications.

Imetelstat is the only drug it has in clinical trials right now.

Since 2008, Good Cookies like YOU have helped fund dozens of pediatric cancer research grants, resulting in NINE promising new treatments moving to clinical trial, now available to children with cancer.

On the heels of a 2013 double - blind clinical trial which showed Axiom Foods» Oryzatein ® plant - based brown rice protein parallels animal - based whey in building and repairing muscle, Oryzatein ® has now become the very first brown rice protein to be granted GRAS approval.

However a lesser known berry — the gooseberry — has now been used in clinical trials to prove its reduction in cardiovascular diseases.

(Culver City, CA April 8, 2014)-- On the heels of a 2013 double - blind clinical trial which proved Axiom Food's Oryzatein ® plant - based brown rice protein equals animal - based whey in building and repairing muscles, Oryzatein has now become the very first brown rice protein to be granted GRAS approval.

With a recent clinical trial showing a 110 % improvement in skin elasticity in just 8 weeks, Osmosis Pür Medical Skincare's Catalyst AC - 11 DNA Repair Serum is now one of the most powerful age reversing serums on the market right now.

«There's more emphasis now and there will be more emphasis because of the Affordable Care Act [on] offering mental health services in primary care settings,» suggests Curry, who is about to start a clinical trial looking at the effects of cognitive behavior therapy for adolescents with depression and substance abuse problems.

Now that they've demonstrated the significance of insulin signaling in the human mammary gland, they are planning a phase I / II clinical trial with a drug used to control blood sugar in type 2 diabetes to determine whether it improves insulin action in the mammary gland, thus improving milk supply.

Findings from the clinical trial now appear as an «article in press» on the Journal of the American College of Surgeons website in advance of print.

The results were published in Nature in 2005 with Helleday as senior author, and PARP inhibitors are now being tested in clinical trials.

«Other people are now moving this into clinical trials in Rett syndrome,» he says.

Many potential Alzheimer's drugs such as Alzhemed, now in its final clinical trial, target amyloid plaque.

Tash, now at the University of Kansas Medical Center in Kansas City, and colleagues began with an anticancer drug that, during clinical trials, severely cut down on sperm production.

In her translational science training program, she says, «I have a bioengineer who can now design a clinical trial.

He now is a co-investigator in the first randomized clinical trial comparing proton therapy with more conventional radiation — something he acknowledges should have happened before so much use.

Now a University of Colorado Cancer Center study published online ahead of print in the journal Oncogene offers compelling evidence explaining this failure and offering a possible strategy for the use of retinoic acid or other retinoids against some breast cancers: Because early clinical trials are often offered to patients who have already tried other more established therapies, breast cancer cells may have been pushed past an important tipping point that offers retinoic acid resistance.

The aromatase inhibitor is now being tested in a clinical trial in France, led by Netchine, who has become a close collaborator and friend of Harbison's.

Mackall's team had already designed a way to make CAR - T cells that attack the GD2 sugar; similar anti-GD2 CAR - T cells are now being tested in clinical trials in a few other cancers.

Investigators now are considering conducting an early - phase clinical trial in which healthy participants would consume a low - asparagine diet.

Clinical trials showed increased hospitalization from dengue in young children who received the shot, which is now licensed in at least 11 affected countries.

Dr. Del Maestro adds, «Yong and colleagues at the University of Calgary have begun to unravel the complex interaction of the microglia with the brain tumor cells, resulting not only in furthering our understanding, but providing a new concept and drug which can now be immediately assessed in clinical trials.»

It is now in a phase II clinical trial in women with ovarian cancer, which almost always has p53 mutations.

The team's samples of 2672 papers, published between 1992 and 2011, showed that all four of these measures have yet to be adopted widely in animal research, though they are now standard practice in clinical trials.

Having performed well in hospital - based clinical trials in 2010, the digital pancreas is now being tested in a real - world environment.

The IU team is now planning studies in animals and, ultimately, will look to others to partner on clinical trials that implement the new treatment in humans.