Sentences with phrase «nuclear genome»

«Because they have the whole nuclear genome, you can really tell a lot about when and where this migration happened,» she says.

This timeline highlights key discoveries about our closest relatives, from early fossil finds to the publication of the draft nuclear genome sequence.

When Pääbo's team looked at patterns of nuclear genome variation in present - day humans, it identified 12 genome regions where non-Africans exhibited variants that were not seen in Africans and that were thus candidates for being derived from the Neandertals, who lived not in Africa but Eurasia.

«Nuclear transfer of mitochondrial DNA in colon and rectal cancer: Mitochondrial DNA moving to the nucleus contributes to genomic instability in cancer cells, and a novel Fiber - FISH technique can rapidly map the mitochondrial DNA insertions in nuclear genomes.»

«The only way to get a real story, the closest we can get, is to sequence nuclear genomes from orchids,» says Victor Albert, a plant geneticist at the State University of New York at Buffalo.

We first used in - solution capture method to enrich the DNA library for human mitochondrial DNA fragments5, 23 to screen for samples with sufficient quality for nuclear genome SNP genotyping.

In any case, however, high quality nuclear genome data from more than one individual would be necessary to fully investigate this proposed wave of human migration out of Africa, and is an intriguing area for future study.

Sequencing nuclear genomes requires sequencing the DNA library many times over, increasing the «depth» of sequence reads at each base.

In contrast, plants with a modified nuclear genome expressed much less dsRNA and only slightly slowed down the beetles» growth.

He is already working on the complete nuclear genome of the Aconcagua boy — which would be even more informative about his family tree and his own unique genetic makeup.

Due to the limited number of specimens and difficulties in obtaining endogenous DNA from such old material, the number of Neandertals for which nuclear genomes have been sequenced is still limited.

«For this reason, ribose - seq has application for rNMP mapping in any genomic DNA, from large nuclear genomes to small genomic molecules such as plasmids and mitochondrial DNA, with no need of standardization procedures,» she said.

They sequenced the entire nuclear genome of this species, and identified all of the genes within that genome that code for biological functions.

You are what you eat: a gene transfer ratchet could account for bacterial genes in eukaryotic nuclear genomes.

Notably, the mean value for the latter individual largely overlaps with the inferred age of 136 — 129 ka from its high coverage nuclear genome analyses, when applying recent estimates of the human mutation rate5.

Researchers were sequencing mitochondrial DNA from aurochs remains (and would successfully sequence the first nuclear genome in 2015).

«Because it is difficult to remove plastid DNA from nuclear DNA, many nuclear genomes available in public repositories contain enough plastid DNA to assemble their corresponding genomes,» explains lead researcher Silvia Garaycochea.

His team ended up with nuclear genome samples from only three mummies, each from a different time period.

But for flies with the same nuclear genome but the «Zim» mitochondrial genome, the balanced diet was just as good, if not slightly better than the high - sugar, low - yeast meals.

The study, published in the journal Science Advances, is the first to obtain nuclear genome data from ancient mainland East Asia and compare the results to modern populations.

Although some of the first extractions of ancient DNA were from mummified remains, scientists have raised doubts as to whether genetic data, especially nuclear genome data, from mummies would be reliable, even if it could be recovered.

Those involved in the California Condor recovery efforts are leading experts in captive propagation and release, and the methods developed and used, particularly those benefiting from whole nuclear genome approaches, acknowledge the importance of maintaining existing genomic diversity both at the individual and population level.

Pääbo's group first gave the field a jolt in May 2010 by reporting a low - coverage sequence (1.3 copies on average) of the composite nuclear genome from three Neandertals.

Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments Wang, Y., R. S. V. D. Hoeven, R. Nielsen, L. A. Mueller et al. 2005.

«The study demonstrates that during a transfer of nuclear genome between two eggs, a small number of mitochondria from donor egg can be accidentally transferred into the recipient egg, which would then result in a mixed mitochondrial genome in the recipient egg.

Here we show variation between incompatible Culex strains in two Wolbachia ankyrin repeat - encoding genes associated with a prophage region, one of which is sex - specifically expressed in some strains, and also a direct effect of the host nuclear genome on CI rescue.

Equivalently important is when the eukaryotic nuclear genome became a chimera with contributions from both the Archaean and Bacteria (Gupta, 1997).

However, targeted resequencing of large parts of nuclear genomes has yet to be demonstrated for ancient DNA.

The leaves were taken from transplastomic dsRNA plants, conventional transgenic dsRNA plants with a modified nuclear genome, and unmodified plants.

We have gone from sequencing small fragments of DNA to full mitochondrial genomes (17,000 base pairs of genetic code), and then in the last three years the field exploded into the realm of complete nuclear genomes.

The study adds to a catalog of ancient genomes, including mtDNA as well as the much larger nuclear genomes, from more than a dozen Neandertals.

Researchers led by Laurent Frantz, an evolutionary geneticist at the University of Oxford in the United Kingdom, sequenced this specimen's entire nuclear genome — the first complete genome from an ancient dog to be published — and compared it to the nuclear DNA of 605 modern dogs from around the world.

But the three mummies with nuclear genome data also show striking genetic continuity, Krause points out.

Both gene products have conserved roles in mitochondrial assembly (mitochondria are made up of 2,000 proteins encoded by the nuclear genome and 13 encoded by the mitochondrial genome), mitochondrial integrity and DNA metabolism.

They showed that although these genomes are separate physical entities, the mitochondrial genome affects the evolution of the nuclear genome, the genetic material responsible for variations in most traits such as hair color and height.

This study found that the interaction between these genomes and the implications on energy production is strong enough that the mitochondrial genome can alter which version of a gene is present in the nuclear genome.

All animal cells are made up of two genomes, the nuclear genome with 10,000 s of protein coding genes and the mitochondrial genome with 13 protein - encoding genes.

Up to now, analysis of mitochondrial DNA inserted into the nuclear genome depended on deep genome sequencing combined with comprehensive computational analysis of the entire genome, a time - consuming, cumbersome and cost - prohibitive approach.

Patients with colon and rectal cancer have somatic insertions of mitochondrial DNA into the nuclear genomes of the cancer cells, University of Alabama at Birmingham researchers report in the journal Genome Medicine.

In a new study, researchers at the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science examined how the interaction of two genomes in animal cells — the mitochondrial and nuclear genomes — interact to affect adaptation of the Atlantic killifish to different temperatures.

This suggests that migration of mitochondrial DNA into the nuclear genome plays an important role in development of cancer, say corresponding authors Hemant K. Tiwari, Ph.D., and Keshav K. Singh, Ph.D..

The somatic mitochondrial DNA inserts appeared to correlate with gene - rich segments of the genome, and the researchers mapped hotspots on the mitochondrial genome for migration into the nuclear genome.

«Also, manipulation of the embryo at that very sensitive time could cause more problems for the nuclear genome, which is why safety data is critical.»

«The problem in older women is the quality of the nuclear genome in their eggs, and adding more mitochondria will not help that problem,» she says.

«For chloroplast genome recovery from total DNA sequence data, the deliberate identification of reads that represent chloroplast DNA inserts into the nuclear genome allowed us to attain a higher - quality chloroplast genome assembly in a time - and cost - effective way,» Garaycochea explains.

According to the researchers, several fragments and, in some cases, nearly entire copies of the chloroplast genome may be found within the nuclear genomes of plants.

Thousands of plant species have had their genomes sequenced, but without organelle genomes, nuclear genomes are only one piece of the DNA puzzle.