Sentences with phrase «nuclear genomes from»

«The only way to get a real story, the closest we can get, is to sequence nuclear genomes from orchids,» says Victor Albert, a plant geneticist at the State University of New York at Buffalo.

Pääbo's group first gave the field a jolt in May 2010 by reporting a low - coverage sequence (1.3 copies on average) of the composite nuclear genome from three Neandertals.

Just 7 months later, the same group published 1.9 copies on average of a nuclear genome from a girl's pinky finger bone from Denisova Cave.

In 2014 alone, scientists successfully sequenced the mitochondrial genome of a hominin that lived more than 400,000 years ago, 1 exomes from the bones of two Neanderthal individuals more than 40,000 years old, 2 and a nearly complete nuclear genome from a 45,000 - year - old modern human fossil, 3 to name but a few.

Not exact matches

Due to the limited number of specimens and difficulties in obtaining endogenous DNA from such old material, the number of Neandertals for which nuclear genomes have been sequenced is still limited.

Researchers were sequencing mitochondrial DNA from aurochs remains (and would successfully sequence the first nuclear genome in 2015).

«For chloroplast genome recovery from total DNA sequence data, the deliberate identification of reads that represent chloroplast DNA inserts into the nuclear genome allowed us to attain a higher - quality chloroplast genome assembly in a time - and cost - effective way,» Garaycochea explains.

The mix of nuclear genes would come from the archaeal guest and later from the mitochondrion, which forfeited parts of its genome to the nucleus over time.

His team ended up with nuclear genome samples from only three mummies, each from a different time period.

Dillon's team, which includes Perri, studied 71 complete mitochondrial genomes and seven nuclear genomes of dogs from more than 20 North American sites, ranging in age from 10,000 to 800 years ago.

The nuclear genome, which contains DNA from both parents, is far more informative.

This timeline highlights key discoveries about our closest relatives, from early fossil finds to the publication of the draft nuclear genome sequence.

The leaves were taken from transplastomic dsRNA plants, conventional transgenic dsRNA plants with a modified nuclear genome, and unmodified plants.

In any case, however, high quality nuclear genome data from more than one individual would be necessary to fully investigate this proposed wave of human migration out of Africa, and is an intriguing area for future study.

When Pääbo's team looked at patterns of nuclear genome variation in present - day humans, it identified 12 genome regions where non-Africans exhibited variants that were not seen in Africans and that were thus candidates for being derived from the Neandertals, who lived not in Africa but Eurasia.

Subsequent sequencing of the nuclear genome followed, revealing that the pinkie came from a previously unknown hominid group, similar to Neanderthals, that migrated east toward Asia while Neanderthals migrated west.

The study adds to a catalog of ancient genomes, including mtDNA as well as the much larger nuclear genomes, from more than a dozen Neandertals.

Researchers also have analyzed the complete nuclear and mtDNA genomes of another archaic group from Siberia, called the Denisovans.

It represents only a small fraction of an animal's genome (the rest is nuclear DNA), and because it is transmitted only from the mother, it reveals just the genetic history of females.

For the study Rand, Zhu and undergraduate co-author Paul Ingelmo generated 18 lines of flies by mixing and matching different mitochondrial and nuclear genomes in individuals from two different species.

And sequencing his nuclear genome — the genetic information inherited from both parents — and that of other ancient specimens could give a more complex picture of the way groups mixed with one another.

An international team of scientists, led by researchers from the University of Tuebingen and the Max Planck Institute for the Science of Human History in Jena, successfully recovered and analyzed ancient DNA from Egyptian mummies dating from approximately 1400 BCE to 400 CE, including the first genome - wide nuclear data from three individuals, establishing ancient Egyptian mummies as a reliable source for genetic material to study the ancient past.

Researchers from the University of Seville at the Andalusian Centre for Molecular Biology and Regenerative Medicine (Centro Andaluz de Biología Molecular y Medicina Regenerativa — Cabimer) have discovered that in eukaryotic cells the proximity of the genes to the nuclear pores, which are found in the nuclear membrane, contributes to maintaining the integrity of the genome.

Yet the discovery shows that with ever - cheaper genetic sequencing and faster computers, it is possible to recover a full nuclear DNA sequence from an ancient human, even when the genome is broken into tiny fragments.

«For this reason, ribose - seq has application for rNMP mapping in any genomic DNA, from large nuclear genomes to small genomic molecules such as plasmids and mitochondrial DNA, with no need of standardization procedures,» she said.

However, since plant tissues harbor three separate genomes (nuclear, chloroplast, and mitochondrial), it can often be challenging to isolate the particular genome of interest from extracted DNA samples.

That precision allows the team to compare the nuclear genome of this girl, who lived in Siberia's Denisova Cave more than 50,000 years ago, directly to the genomes of living people, producing a «near - complete» catalog of the small number of genetic changes that make us different from the Denisovans, who were close relatives of Neandertals.

By comparing this composite Neandertal genome with the complete genomes of five living humans from different parts of the world, the researchers found that both Europeans and Asians share 1 % to 4 % of their nuclear DNA with Neandertals.

The structure shows that the genome is arranged such that the most active genetic regions are on the interior and separated in space from the less active regions that associate with the nuclear lamina.

In an interdisciplinary team effort, we study the conformation of the genome at various scales, from the nucleosome fiber to the distribution of chromosomes territories in the nuclear space.

To avoid including reads sequenced from regions of the nuclear genome sharing high similarity with mitochondrial DNA (NUMTs), reads that did not map uniquely to the mitochondrial genome were discarded using SAMtools [32, 33].

Using high - resolution quantitative approaches, her laboratory investigates how gene expression is regulated from both the nuclear and mitochondrial genomes.

We have gone from sequencing small fragments of DNA to full mitochondrial genomes (17,000 base pairs of genetic code), and then in the last three years the field exploded into the realm of complete nuclear genomes.

Inserting it into the nuclear genome helps to protect the gene from oxidative damage, while our tagging system will help guide the functional protein into the mitochondria where it is needed.

We are able to call 22 million high quality single nucleotide polymorphisms (SNP) from the nuclear genome, representing the largest SNP call set from an East Asian population to date.

With a given read depth of 31X, the assemblies from both Pacific Biosciences and Oxford Nanopore MinION show excellent continuity and completeness for the 16 nuclear chromosomes, but not for the mitochondrial genome, whose reconstruction still represents a significant challenge.

In the absence of a population suitable for GWAS, we utilized genome - wide SNP profiles from a nuclear family to evaluate inheritance patterns in chromosomal regions harboring all 18 candidate genes.

With recent announcements of plans for sequencing the genome from present - day polar bear (34) offering a necessary reference, future sequencing of all or a substantial fraction of the nuclear genome of this exceptionally well preserved Pleistocene polar bear specimen may be feasible.