Sentences with phrase «nuclear import»
The phrase "nuclear import" refers to the process by which molecules or substances are transported into the nucleus of a cell. It is like allowing specific items to enter a protected area within the cell. Full definition
Thus, p10 appears to coordinate the Ran - dependent association and dissociation reactions underlying nuclear import.
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Bioinformatic analyses suggest that glycine - arginine and proline - arginine repeats could mimic the nuclear localization signals of these proteins and hence hijack nuclear import by overloading the nucleocytoplasmic transport system.
Her lab studies both directions of signaling between synapse and nucleus, focusing on 1) the role of the active nuclear import pathway in transport of signals from synapse to nucleus and 2) mRNA localization and regulated translation as a mechanism for spatially restricting the products of gene expression to specific synapses within a single neuron.
A cytosolic yeast karyopherin, Kap104p, was isolated and shown to function in the nuclear import of a specific class of proteins.
The nuclear import factor p10 was cloned from Saccharomyces cerevisiae and found to be essential.
Additionally, by engineering FP fusions associated with cellular organelles, scientists have been able to study many cellular processes, including mitosis, mitochondrial fission / fusion, nuclear import, and neuronal trafficking.
The nuclear import of unphosphorylated STAT2 depended on its association with IRF - 9, which contained a constitutive nuclear localization signal (35).