Sentences with phrase «nuclear localization signal»

The nuclear import of unphosphorylated STAT2 depended on its association with IRF - 9, which contained a constitutive nuclear localization signal (35).

Interferon regulatory factor subcellular localization is determined by a bipartite nuclear localization signal in the DNA - binding domain and interaction with cytoplasmic retention factors

Bioinformatic analyses suggest that glycine - arginine and proline - arginine repeats could mimic the nuclear localization signals of these proteins and hence hijack nuclear import by overloading the nucleocytoplasmic transport system.

Inhibits the activity of dimeric NF - kappa - B / REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals.

Critically, the absence of dimerizer ligand in the target cell culture medium and the presence of a nuclear localization signal on the Cas9 endonuclease ensures that the complex dissociates from the red fluorescent protein and is transported to the nucleus.

Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1 - dependent nuclear export.