Sentences with phrase «nuclear membrane»
The nuclear membrane is a layer that surrounds the nucleus in a cell. It acts as a protective barrier, like a skin, and helps to control what enters and leaves the nucleus. Full definition
Not only were selected «test» genes that served as markers turned off after being attached to the inner nuclear membrane, but also nearby «real» genes.
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This could be tremendously important,» she said, «for understanding the underlying cause of some diseases that result from mutations in genes encoding inner nuclear membrane proteins.»
It is expected to have implications for other tissue - specific nuclear membrane conditions, such as fat, skin, bone and brain diseases, cardiomyopathy and an ageing disease known as progeria.
Compared with the nucleus of a normal fly neuron (left), one from a fly with a common ALS mutation has a damaged nuclear membrane (right) with clusters of nuclear pore protein (red) around its edges.
Mo engineered mice that carried a gene for a tagged nuclear membrane protein Henry had designed, SUN - 1, which would be turned on only in cells that made another protein, Cre.
Sullivan's research has shown that chromosome fragments don't segregate with the rest of the chromosomes, but get pulled in later just before the newly forming nuclear membrane closes.
They contain a special nuclear membrane to protect the DNA, additional membranes and structures like mitochondria and Golgi bodies, and a variety of other advanced features.
«So we think that these proteins are part of the molecular machinery that is used for positioning genes at the inner nuclear membrane, as well as potentially for repressing them,» he said.
Sweet potatoes contain many anticancer properties, including beta - carotene, which may protect DNA in the cell nucleus from cancer - causing chemicals outside the nuclear membrane.
The mitochondria are located in the cytosol of the cells, outside of the cell nucleus; the cell's DNA genome is located inside the nuclear membrane.
First, although the membrane surrounding the nucleus appears similar to those of mitochondria and chloroplasts, all of which have two layers, the nuclear membrane is unique.
Researchers from the University of Edinburgh studied newly discovered muscle - specific proteins, found in a membrane that surrounds the DNA in each of our cells — known as the nuclear membrane.
Researchers from the University of Seville at the Andalusian Centre for Molecular Biology and Regenerative Medicine (Centro Andaluz de Biología Molecular y Medicina Regenerativa — Cabimer) have discovered that in eukaryotic cells the proximity of the genes to the nuclear pores, which are found in the nuclear membrane, contributes to maintaining the integrity of the genome.
Bräuchle suggests that the tracks are tube - shaped invaginations of the nuclear membrane, recently discovered structures never before known to ferry viruses.
During meiosis, telomeres allow chromosomes to attach to the nuclear membrane, thus allowing them to exchange DNA fragments.
Various tube - and sheet - like extensions of the nuclear membrane form what is called the endoplasmic reticulum or ER, which is involved in protein transport and maturation.
In their Nature paper, Singh's team also showed for the first time that this transcriptional repression was dependent on breakdown and reformation of the nuclear membrane during cell division.
«In cells that don't produce antibodies, like fibroblasts or T - cells, these antibody genes are attached to the inner nuclear membrane and are not recombined or expressed,» said Singh.
In this study, the authors developed the molecular tools to take specific genes from these interior compartments, move them to the periphery and attach them to the nuclear membrane — which turned those genes off.
Attachment to the inner nuclear membrane, they show, can silence genes, preventing their transcription — a novel form of gene regulation.
The investigators reasoned that, while their constructs» appended RP import sequences can facilitate mitochondrial import, that ability can not be exploited if the transcripted constructs are not actually shuttled from the nuclear membrane to the mitochondrial surface for import.
The likely suspects, said Singh, are some of proteins that reside in the inner nuclear membrane.
Sulforaphane actually locks onto a receptor on the cell's nuclear membrane to help shut down the genetic machinery that produces CYP 3A4.