Nonetheless, on page 1168 of this issue, Wilson et al. (2) report the facile
nucleophilic alkylation of benzene accomplished through highly reactive alkylcalcium nucleophiles.
Kobayashi K, Narumi T, Oishi S, Ohno H, Fujii N. Amino acid - based synthesis of trifluoromethylalkene dipeptide isosteres by alcohol - assisted
nucleophilic trifluoromethylation and organozinc - copper - mediated S (N) 2»
alkylation.