Li M, Hada A, Sen P, Olufemi L, Hall MA, Smith BY, Forth S, McKnight JN, Patel A, Bowman GD, Bartholomew B, Wang MD. (2015) Dynamic regulation of transcription factors by
nucleosome remodeling.
Not exact matches
Neither the mechanism of their action nor the conformation of the
remodeled nucleosomes are, however, yet well understood.
The data illustrates how RSC
remodels the
nucleosome in vitro and shed light on its in vivo function.
BAZ2A is an essential component of the nucleolar
remodeling complex (NoRC), which mediates recruitment of histone modifyine enzymes and DNA methylase involved in the silencing of ribosomal RNA transcription by RNA polymerase I. BAZ2B is believed to be involved in regulating
nucleosome mobilization along linear DNA.