Sentences with phrase «nucleotide bases at»

With four nucleotide bases at the cell's disposal, 64 codons are possible: One to six codons specify each of the 20 natural amino acids most commonly used, and three tell the cell to stop building the protein.

Biochemist Nirenberg of the National Institutes of Health gave a seminar describing a groundbreaking experiment in which he and a colleague had discovered how the cell interprets messenger RNA — by reading one triplet, or codon, of nucleotide bases at a time — to line up the amino acids that form proteins.

Not exact matches

One commercially available alternative is pyrosequencing, which also detects nucleotides as they are added to a single strand of DNA, but it can lead to errors because it is harder to differentiate between a single base and a whole stretch of identical bases next to each other, says Elaine Mardis, a geneticist at Washington University in St Louis, US.

We have determined at 2.1 angstrom resolution the crystal structure of a T7 RNAP elongation complex with 30 base pairs of duplex DNA containing a «transcription bubble» interacting with a 17 - nucleotide RNA transcript.

Gregory Koblentz, deputy director of the biodefense program at George Mason University in Fairfax, Virginia, speculates that the FBI may have used a recent technique based on the identification of Single - Nucleotide Repeat markers in the anthrax genome that allows for differentiating between variants of the same strain.

Based on the nucleotide context, the authors suggest that a new mutational mechanism may be at work involving cytosine deamination of single - stranded DNA (presumably during replication).

FRT sites and loxP sites differ at the nucleotide level but share an overall structure of 13 base pair palindromic repeats separated by an 8 bp asymmetric core.

A single DNA sequence is formed from a chain of four nucleotide bases and if some individuals in a population do not carry the same nucleotide at a specific position in the sequence, the variation is classified as an SNP.

Four types of reversible terminator bases (RT - bases) are added and the sequencing strand of DNA is extended one nucleotide at a time.

«By combining different methods for RNA sequencing with new bioinformatics tools we could find novel sites of nucleotide base exchange, so - called editing», says Jens Lagergren, Professor at the Royal Institute of Technology and group leader at SciLifeLab Stockholm.

The hairpin precursor shows imperfect complementarity, and base pairs in at least 16 of the ~ 22 nucleotides.

A consensus sequence based on mapped deep sequencing reads was generated for each of the prostate cancer XMRV genomes and used to correct errors in the previously published sequences, with the requirement of no ambiguity at each discrepant nucleotide position.