Sentences with phrase «nucleotide changes as»

Not exact matches

The increase, observed as early as 60 seconds after the addition of corticotropin - releasing factor, suggests that changes in the intracellular concentration of the cyclic nucleotide coincide with or precede the secretion of adrenocorticotropic hormone in response to corticotropin - releasing factor.

Rather than measuring genetic changes directly (such as single nucleotide polymorphisms, otherwise known as SNPs), McKee and her group typically do RNA expression profiles on patients to see what genes are being expressed.

Making changes to only five nucleotides in the β - actin gene, they were able to transform it so that its amino acid output would be exactly the same as the γ - actin protein.

The assembly and analysis of human tumor cell genomes, many of which contain chromosome deletions, duplications and insertions, as well as single nucleotide changes, requires immense data storage capacity and high - speed computation.

CRISPR / Cas9 and related tools can now be used in new ways, such as changing a single nucleotide base — a single letter in the genetic code — or adding a fluorescent protein to tag a spot in the DNA that scientists want to track.

As expected, the mutational spectrum was enriched for G - > T and C - > A changes associated with adduct formation on guanine nucleotides induced by benzopyrene, the chemical mutagen found in tobacco smoke.

In addition to the large CNV mutations they had spotted earlier, they also found de novo changes in single base pairs of DNA — known as single - nucleotide variants (SNVs)-- and small de novo insertions or deletions in chromosomes, all of which made the picture even more complex.