Sentences with phrase «nucleus of a cell»

By our nature we must crack the nucleus of the cell — from the human we jump to the «ultrahuman» and someday doubtless the doublesuperultrahuman.

DNA never leaves the nucleus of the cell; its molecular recipes are read out in the form of messenger RNA, which leaves the nucleus and enters the cytoplasm, where proteins are made.

Settling this disputed ancestry required DNA from within the nucleus of a cell — something far more difficult to obtain and analyze.

Bands on gels that form the Manhattan skyline, graphs that resemble comedy breasts, or smiley faces hidden in the nuclei of cells are the mainstay of every lab notice board, but they rarely make it to publication.

YAP can be found in the cytoplasm but also the nucleus of a cell, and when it is in the nucleus, YAP regulates gene expression.

And while cytochalasin D might not be the actual agent scientists use to trigger bone formation in the clinic, Rubin's study shows that triggering actin transport into the nuclei of cells may be a good way to force mesenchymal stem cells to become bone cells.

In the organoids, the scientists found such mechanical instability in two places: the cytoskeleton — the internal skeleton — of the cells in the center of the organoid contracted, and the nuclei of the cells near the surface expanded.

Vitamin A and vitamin D are precursors to hormones that influence biological processes by entering the nucleus of a cell, binding to DNA, and altering the transcription of certain genes.

Disease processes often begin with mutations in the transcription factor, or in the DNA they bind to inside the nucleus of cells to regulate the complex interplay of genes needed for a healthy functioning body.

Histone is a protein that acts like a spool for DNA, helping to package the six - foot long DNA strand into the tiny nucleus of every cell.

The green staining indicates the cortical marker CTIP2, the red stain is the neuronal marker TUJ1, and the blue stains the nuclei of the cells.

Our genetic heritage is contained — and protected — in the nucleus of the cells that compose us.

Seeking to take advantage of these traits, scientists can reprogram viruses to function as vectors, capable of carrying their genetic cargo of choice into the nuclei of cells in the body.

Splicing largely takes place within the nucleus of cells, where many Rbfox1 proteins are found.

The cellular proteins are located in the nucleus of the cell, where the virus maintains its genetic material.

Residing in large numbers outside the nucleus of every cell, mitochondria contain their own DNA, with unique features that «may require a reassessment of some of our core assumptions about human genetics and evolutionary theory,» concludes Wallace, director of the Center for Mitochondrial and Epigenomic Medicine at The Children's Hospital of Philadelphia.

To tackle the challenge, the team developed a new approach, called 3D assembly, which determines the sequence of each chromosome by studying how the chromosomes fold inside the nucleus of a cell.

All nuclei of the cells are shown in blue and a certain leukocyte subpopulation in purple.

Rather than disentangling entire cells, HHMI investigator Steven Henikoff and postdoctoral researcher Roger Deal at the Fred Hutchinson Cancer Research Center had simplified the problem by isolating only the nuclei of the cells they were interested in.

Although in rare cases mitochondrial genes may be transferred to the nucleus of a cell, she said the IU team found no evidence to suggest this is the case in V. scurruloideum, and that further investigation will be required to reveal the exact mechanism through which the species compensates for its missing genes.

When a cell is oxygen starved, the enzymes that inactivate HIF - 1α instantly cease to function, allowing HIF - 1α to escape destruction, enter the nucleus of the cell, and trigger an alarm that instructs genes to adapt to a low - oxygen microenvironment.

The nucleus of a cell is spherical, not circular, and as scientists, it's up to us to find ways to observe cells as accurately as possible, Shroff said.

Like jewels in a vault, our precious genetic material is stored in the nucleus of a cell — sequestered away from potentially damaging cellular components and toxins so that no harm can come to it.

Almost 10 years ago, the Eberwine lab discovered that nerve - cell dendrites have the capacity to splice messenger RNA, a process once believed to take place only in the nucleus of cells.

After many attempts, CC was created by coaxing the nucleus of a cell from a calico cat into an enucleated egg; an electrical spark prompted the hybrid to divide, and the resulting embryo was then transferred into a surrogate mother.

Blue indicates nuclei of cells.

Scientists clone an animal by taking an egg cell, removing its genetic material, and replacing it with the nucleus of a cell from the animal they wish to clone — in Dolly's case, a mammary cell from a 6 - year - old sheep.

Within the nucleus of each cell, long strands of DNA encode an organism's genes by combining just four chemical building blocks — adenine, guanine, cytosine, and thymine.

Nuclei of all cells are stained blue with DAPI.

Apart from that, the team has managed to show that the ANKRD55 proteins reside in the nuclei of the cells, and that suggests that they could play a significant role in the specific processes that take place in the cell nucleus such as gene transcription.

Similarly, other epigenetic changes occur in how DNA and proteins are compacted in the nucleus of the cell.

The Ostrer study used DNA from the nucleus of the cell in its analyses, and the Behar study used both nuclear and mitochondrial DNA (mtDNA); the latter comes from tiny bodies in the living cell that provide it with energy.

Transcription factors, the tiny proteins that switch genes on or off in the nucleus of cells, are considered unreachable molecular targets for drugs attempting to treat medical conditions.

SATB2 is a DNA - binding protein that facilitates structural organization of chromosomes in the nucleus of cells.

RCM - 1 treatment removes a transcription factor called FOXM1 (shown in green) from the nucleus of cells (blue) to the cell cytoplasm.

Asf1 act as a freight train that transports histones to the nuclei of our cells where the DNA is copied during cell divisions.

DNA and genes — which house the instructions for making proteins — are stored within the nucleus of each cell.

In guarding the cell against genetic damage, the p53 machinery functions both in the nucleus of the cell and in the cell's gel - like cytosol.

In Figure 5O, the number of rod photoreceptor, inner nuclear layer, and retinal ganglion cells were determined by counting the nuclei of cells expressing XAP2, Calretinin, or in the RGC layer, respectively.

The RNA finds the spot in the nucleus of a cell where some editing activity should take place.

But nobody understood how PER was getting into the nuclei of the cells where it would act on the period gene.

Many other molecules are also involved in this process, including epigenetic regulators that help to densely pack the genome into the nucleus of a cell, or locally unpack it to allow gene expression.

An international team of biologists has discovered how specialized enzymes remodel the extremely condensed genetic material in the nucleus of cells in order to...

The Sarma laboratory is interested in the mechanisms of epigenetic gene regulation, or how the dynamic modifications of the architecture of chromatin, the complex of DNA and proteins within the nucleus of our cells, impacts gene expression and cellular function.

We investigate how changes to DNA organization within the nucleus of a cell impact development and disease.

In this study, the team delved deep into the nucleus of cells belonging to mouse and zebrafish embryos — two important animal models of embryonic development — in order to determine how the Dll4 gene is turned on.

The nuclei of the cells were also stained to differentiate between neurons and glia, allowing researchers to then count the cell nuclei that belong to neurons.

Over the past two decades, researchers have used various AAVs as vehicles to transport specific genes into the nuclei of cells; once there, the genes can be expressed, or translated, from DNA into proteins.

In the inherited form researched in the current study, this includes a deficiency of the protein progranulin, which is tied to the mislocalization of another crucial protein, TDP - 43, from the nucleus of the cell out to the cytoplasm.

Nuclei of all cells in the sample are stained with DAPI (blue fluorescent: left).