The p21 -
null mice also developed epithelial tumors (Table 2) ⇓.
Not exact matches
We have
also examined the constitutive levels of apoptosis in the thymic lymphomas developed in p21 -
null mice and in wild - type
mice after irradiation (Fig. 4) ⇓.
In this study, we have addressed the role of p21 in tumor suppression by directly assessing the susceptibility of p21 -
null mice to spontaneous tumors and
also to radiation - induced tumors.
For comparison, we have
also followed in parallel a colony of 30 wild - type
mice of the same genetic background as the p21 -
null mice (i.e., C57BL6 / 129Sv 50:50).
Called immunodeficient IL2 receptor gamma (IL2rl)
null mice, these animals lack the IL2ry receptor that humans
also have as part of a functional immune system.
The previously established function of Boule in meiotic progression in both Drosophila and nematodes [39], [40] may
also be conserved in
mice, despite the lack of a similar meiotic defect in Boule
null mice [61].