Analysis of Sema3B
null mice showed they were viable, fertile, and displayed no overt pathological abnormalities, suggesting an inherent correction mechanism or level of redundancy between the class 3 semaphorins.
«The J20 / caspase -2
null mice showed the same dendritic spine density and morphology as the normal mice — as opposed to the deficits in the J20 mice,» said co-lead author Julio Pozueta, PhD.
Not exact matches
Analysis of the neurons
showed that the J20 / caspase -2
null mice had a higher density of dendritic spines than the J20
mice.
We have considered the possibility that radiation could directly result in more apoptosis in the thymus of p21 -
null mice; however, quantitation of sub -(G0 / G1) thymocytes after acute irradiation (10 Gy; and analysis 3 h after irradiation) has not supported this idea (data not
shown).