Not exact matches
STOP SIGNS Brainlike structures grown from autistic patients»
stem cells (right) produced greater
numbers of brain cells that make other
brain cells less active (green and red) compared with structures grown from the
cells of a non-autistic family member (left).
Shah next plans to rationally combine the toxin - secreting
stem cells with a
number of different therapeutic
stem cells developed by his team to further enhance their positive results in mouse models
of glioblastoma, the most common
brain tumor in human adults.
Prior research with cultured tissue had shown that a mix
of chemicals could change bone marrow
stem cells from mice to those resembling
brain cells, but when a team led by neurologist Lorraine Iacovitti
of Thomas Jefferson University in Philadelphia tried the same brew on human
cells, the
number altered was modest.
The team found that people have large
numbers of neural
stem cells and progenitors early in life — an average
of 1618 young neurons per square millimeter
of brain tissue at birth.
Neuroscientists Jing Wang and Freda Miller, both then at Toronto's Hospital for Sick Children, showed that when nondiabetic mice are given metformin, their memory improves, thanks to an increase in the neural
stem cell population and in the
number of these
cells that develop into healthy neurons in the hippocampus, the
brain's memory center.
During the initial stages
of typical
brain development,
stem cells go through a period in which they divide to make more
stem cells, increasing their
numbers.
They observed a significant decrease in the
number of proliferating
stem cells in the
brains of HIV / gp120 - mice compared with similar tissue from normal, wild - type mice.
Unfortunately, the
number of adult
stem cells present in local areas
of the body vary greatly in
number and most researchers agree that there are simply not enough
stem cells «at the ready» within
brain tissue to heal itself in the same way the skin does after a cut.