Crossovers are essential for segregating the correct
number of chromosomes into each gamete.
Not exact matches
As all school - children learn, cells divide using a process called mitosis, which consists
of a
number of phases during which duplicate copies
of the cell's DNA - containing
chromosomes are separated
into two distinct cells.
During the key step in sperm formation — a division that results in two cells, each with half the original
number of chromosomes — the X and Y
chromosomes peeled off from the chain one by one and headed
into separate cells, all segregating faithfully with their own kind.
If the cells reduce the copy
number of this specific
chromosome again — say upon another change in environmental conditions — then they turn back
into a smooth colony.
But to complete their maturation
into sperm, which have half the
number of chromosomes of nongerm cells, these PGC - like cells were transplanted back
into mouse testes.
After transforming MDS skin cells
into iPSCs, the team looked at the
number and structure
of all 23 pairs
of chromosomes inside each cell.