A large number of these companies are clustered in Toronto, Montreal, Vancouver, Ottawa, and Saskatoon and provide a significant
number of drug discovery jobs in those areas.
Not exact matches
From accelerating the identification and validation
of novel therapeutic targets, to creating better animal models
of human diseases in a shorter time frame, to reducing the
number of failed products, Crispr looks set to shave millions off R&D costs and boost
drug discovery, she says.
In the March 19, 2004, issue
of Science — dedicated to
drug discovery — Phil Szuromi, Valda Vinson, and Eliot Marshall wrote: «In recent years, the number of new drugs approved annually by the U.S. Food and Drug Administration has at best stayed steady, despite large increases in R&D investment.&ra
drug discovery — Phil Szuromi, Valda Vinson, and Eliot Marshall wrote: «In recent years, the
number of new
drugs approved annually by the U.S. Food and
Drug Administration has at best stayed steady, despite large increases in R&D investment.&ra
Drug Administration has at best stayed steady, despite large increases in R&D investment.»
But, although modern technologies are accelerating the
number of compounds that companies can produce and analyse, in Canada there has not been a dramatic increase in the
number of jobs created for
drug discovery scientists.
At CeMM, a
number of key
discoveries on new applications for approved
drugs have already been made with the CLOUD.
CADD, or «rational
drug discovery,» helps make it possible to select a more manageable
number of candidates that can then be tested experimentally.
As nanotechnology to ferry
drugs to their destinations is tested in both the laboratory and in clinical trials, scientists have made a surprising
discovery about the kinds
of nanoparticles that might be most effective for eventually transporting a
number of different cancer - fighting therapies throughout the body.
«Messenger RNA therapeutics ™ promises to vastly expand the
number of diseases we can treat and usher in an entirely new era
of drug discovery and development,» said Stéphane Bancel, president and founding CEO
of Moderna.
Prior research had developed a
number of new compounds making use
of a novel
drug discovery paradigm which begins with natural products extracted from plants; it then entails selecting synthetic derivatives which demonstrate efficacy in multiple assays testing protection against different factors
of the nerve cell damage and death which take place in brain injuries and in age - associated neurodegenerative conditions.
«But the lead author
of the study... says that he is not convinced that it is just the changing climate... «It could be partly due to this chaotic rainfall, but personally I don't think it can explain such a dramatic decline in mosquitoes, to the extent we can say that the malaria mosquitoes are almost eradicated in these communities... «What we should consider is that there may be a disease among the mosquitoes, a fungi or a virus, or they're may have been some environmental changes in the communities that have resulted in a drop in the
number of mosquitoes»... The research team also found anecdotal evidence that their
discovery was not an isolated case... «Other scientists are saying they can't test their
drugs because there are no children left with malaria.»»