Sentences with phrase «number of effects which»

There are also a number of effects which can have a large impact on short - term temperatures, such as oceanic cycles like the El Niño Southern Oscillation or the 11 - year solar cycle.

Not exact matches

Any chilling effect on diplomatic relations could also affect the Chinese market's strict and complicated regulatory system, which limits the number of foreign - made movies that are released in the country each year.

As fracking became commercially viable, oil and gas drilling companies entered communities with shale gas resources, which can have a number of local effects.

«There are a number of other significant changes to the unfair dismissal regime which will have far - reaching effects.

Companies like U.S. biotech giant Gilead and the U.K.'s GlaxoSmithKline (the majority stakeholder in global HIV partnership ViiV Healthcare) have developed drugs that drastically lower the chance of HIV infection — or which simply lower the number of drugs you have to take to treat it, consequently curbing the risk of toxic side effects while simplifying medical regimens.

The result: a multiyear, multinational, ongoing research project known as the Global Entrepreneurship Monitor, or GEM, which counts (in effect) the number of working - age adults who are engaged in acts of company creation.

«Our success is primarily dependent on audience acceptance of our films, which is extremely difficult to predict and, therefore, inherently risky... Our business is currently substantially dependent upon the success of a limited number of film releases each year and the unexpected delay or commercial failure of any one of them could have a material adverse effect on our financial results and cash flows.»

Worse, Facebook has likely worsened or maybe even created the «filter bubble» effect in which a growing number of us mostly or only hear news that reinforces the beliefs we already hold.

The new law, which received initial approval from the city, is expected to take effect in February and comes with a number of requirements for hosts using the site.

It is a condition that afflicts people who have too many passwords, frequently forget their login information, and succumb to a number of side effects, which include crying, screaming, and banging their heads on their desks.

The ability to talk back, send comments or share a link (all of which generate positive impact with minimum effort) has the same psychological effect, which is why an increasing number of websites are choosing to use this technique.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

And those numbers overstate the effect of bond fund trading because they exclude bond trading at regional brokerages, which play a large role in the municipal securities market.

After the financial crisis, global bank regulatory bodies established a number of new banking regulations which are having important effects on the credit machine.

Actual results may vary materially from those expressed or implied by forward - looking statements based on a number of factors, including, without limitation: (1) risks related to the consummation of the Merger, including the risks that (a) the Merger may not be consummated within the anticipated time period, or at all, (b) the parties may fail to obtain shareholder approval of the Merger Agreement, (c) the parties may fail to secure the termination or expiration of any waiting period applicable under the HSR Act, (d) other conditions to the consummation of the Merger under the Merger Agreement may not be satisfied, (e) all or part of Arby's financing may not become available, and (f) the significant limitations on remedies contained in the Merger Agreement may limit or entirely prevent BWW from specifically enforcing Arby's obligations under the Merger Agreement or recovering damages for any breach by Arby's; (2) the effects that any termination of the Merger Agreement may have on BWW or its business, including the risks that (a) BWW's stock price may decline significantly if the Merger is not completed, (b) the Merger Agreement may be terminated in circumstances requiring BWW to pay Arby's a termination fee of $ 74 million, or (c) the circumstances of the termination, including the possible imposition of a 12 - month tail period during which the termination fee could be payable upon certain subsequent transactions, may have a chilling effect on alternatives to the Merger; (3) the effects that the announcement or pendency of the Merger may have on BWW and its business, including the risks that as a result (a) BWW's business, operating results or stock price may suffer, (b) BWW's current plans and operations may be disrupted, (c) BWW's ability to retain or recruit key employees may be adversely affected, (d) BWW's business relationships (including, customers, franchisees and suppliers) may be adversely affected, or (e) BWW's management's or employees» attention may be diverted from other important matters; (4) the effect of limitations that the Merger Agreement places on BWW's ability to operate its business, return capital to shareholders or engage in alternative transactions; (5) the nature, cost and outcome of pending and future litigation and other legal proceedings, including any such proceedings related to the Merger and instituted against BWW and others; (6) the risk that the Merger and related transactions may involve unexpected costs, liabilities or delays; (7) other economic, business, competitive, legal, regulatory, and / or tax factors; and (8) other factors described under the heading «Risk Factors» in Part I, Item 1A of BWW's Annual Report on Form 10 - K for the fiscal year ended December 25, 2016, as updated or supplemented by subsequent reports that BWW has filed or files with the SEC.

The absence of the securitisation market has had a particularly significant effect on those institutions most reliant on it, which includes a number of the non-conforming lenders.

In a scalable business network effects are strong, which increases the value of the product or service as the number of customers grows

Although it was popular overall, a number of interesting sources indicate that this policy may actually cause staff to take less time off than usual, which has detrimental effects on their well - being.

Employment insurance benefits increased $ 1.2 billion, (6.7 %), primarily reflecting legislative changes, which came into effect in July 2016, and also to an increase in the number of people eligible for EI benefits.

Among them was a large number of companies seeking initial public offerings in the mainland, which had the temporary effect of locking up about 5 trillion renminbi, or more than $ 810 billion, in investors» funds.

The per - Share number of Bitcoins exchanged for a purchase or redemption is calculated daily by the Trustee, using the Blended Bitcoin Price, or such other publicly available price as the Sponsor may deem fairly represents the commercial value of the Trust's Bitcoins, for the Bitcoins being valued to calculate the Bitcoin amount in respect of any liabilities for which covering Bitcoins sales have not yet been made, and represents the per - Share number of Bitcoins held by the Trust, after giving effect to its liabilities, sales to cover expenses and liabilities and any losses that may have occurred.

Our most recent Constitutional Amendment, number 27, adopted in 1992, which prohibits any law that increases or decreases the salary of members of the Congress from taking effect until the start of the next set of terms of office for Representatives, was first introduced by James Madison in 1789.

But the increasing number of two - salary homes has tended to make clergy less concerned about salary standards, and this change has a negative effect on the family in which the wife wishes to remain in the home full - time, for one reason or another.

So, we see a major financial and economic crisis beginning with deflation in a certain number of countries such as Japan, which had major effects on countries such as South Korea and Brazil, and also on developed countries where all the countries of the North and South are starting to move into recession.

While it is of course true that those who belong to this school are perhaps most vocal in their assertion that in our Lord alone may God be seen at work, and while it is they who denounce the concept of «general» revelation as a vain fancy of sub-Christian speculation, a considerable number of other Christian thinkers take what in effect is the same position when they make central to their teaching a kind of uniqueness in the coming and the person of Christ which effectively removes him from the context of the total sell - expressive operation of the Eternal Word.

The counter-argument resides in his citation and defense of G. J. Whitrow's argument2 to the effect that an infinitist is committed to the idea of an infinite number of intermediary past events which ex hypothesi ought to be able to be counted or successively synthesized (but which everyone agrees can not be), and that this very situation of infinite intermediaries obliterates the intuitively sound distinction between actual past and potential future.

Creed filmmaker Ryan Coogler, Selma director Ava DuVerney, comedian Hannibal Buress, musicians Stevie Wonder and Janelle Monáe and several others hosted an event in Flint to raise money for the community that has been effected by a horrific crisis, in which thousands of residents — including large numbers of children — have been exposed to contaminated city water.

There are a number of ways in which evangelicals are whittling away at the doctrine of separation, and in effect are «standing the founding fathers on their heads.»

While religious perspectives have nothing to do with the technical content of a lecture, they are relevant to a number of aspects of the academic situation.1 Where appropriate to the objectives of the course and closely connected with the subject matter, some of the questions which we have raised about the effects of an invention on society or the ethical dilemmas faced by the scientist can legitimately be mentioned in the classroom.

That there may be some who need compulsion, some who, if they were free - footed, would riot in selfish pleasures like unruly beasts, is doubtless true; but a man must prove precisely that he is not of this number by the fact that he knows how to speak with dread and trembling; and out of reverence for the great one is bound to speak, lest it be forgotten for fear of the ill effect, which surely will fail to eventuate when a man talks in such a way that one knows it for the great, knows its terror — and apart from the terror one does not know the great at all.

Such is the sublime transformation which we may with justice foresee, and which in fact is beginning to have its effect upon a growing number of minds, freethinkers as well as believers: the idea of a spiritual evolution of the Universe.

The next stage was to accept that in many entities we have to consider a large number of interacting components, and processes of cause - effect which are not simply linear, but may interest either by being linked into networks, or by various types of feed - back interaction, positive or negative and so on.

Another effect of the growth of paid - time religious programs is the steady increase in the number of stations that now see religion primarily as a commercial venture and for which payment for air - time has become the dominant principle in the broadcasting of religion.

The body converts lauric acid into monolaurin, which is believed to have strong antiviral and antibacterial effects that can destroy a number of disease - causing organisms.

Such of these other manufacturers, including defendant, whose use of the word «Tabasco» came to the knowledge of plaintiff and its predecessors, have been warned to the effect that they have no right to use the word in connection with the sauce, or to use similar packages, and quite a number of suits for infringement have been filed by plaintiff, most of which have been terminated by consent decrees.

Since 2002, the balls used at Coors have been stored in an MLB - approved humidor to counteract the effects of altitude, which has curtailed the number of dingers there.

N'Jie is all set to join Marseille on loan with a quasi-obligatory $ 7m buy clause, which will come into effect after the Cameroonian international plays a certain number of matches for OM and as long as the club is not relegated to Ligue 2.

Divock Origi is an interesting one, he has all the attributes to become a really good number 9, he's fast, strong and is reasonable in the air but his main weakness seems to be his lack of footballing intelligence which seems to really effect his game.

Cardiff did suffer from Liverpool's creativity in the first half, but were able to avoid a demolition and put in an admirable second half performance, with a number of key battles taking place which had an effect on the balance of the game:

If the pundits are right about one thing, it is that in certain areas (either end of the pitch), we're short on numbers, which means we can't play Everton, Napoli and City in six days without it having a tangible effect.

Comparing the heart rate or blood sugar levels of a given number of people might be beneficial in determining the range in which people maintain good health — and perhaps we can even say that by comparing children's abilities and establishing a range of «normal,» we can determine which children have difficulties and how to help them — but comparing ourselves with others, and in particular our children to other children, can have very damaging effects.

A large number of ovaries increases the chance of pregnancy, but unfortunately has also been associated with ovarian hyperstimulation syndrome (OHSS), which is sometimes called the most important side effect of fertility treatment.

Finding a way to reconcile two competing demands - minimizing contact in practice in order to reduce the number of concussions sustained and the number of hits players sustain over the course of a week and a season that emerging science, now more than ever, suggests may have a deleterious cumulative effect [26] on a player's cognitive function over the long term, while at the same time maximizing the amount of time in practice learning how to tackle and block without head - to - head contact - time that is needed to maximize the protective effect of proper tackling on the number of head - to - head hits players sustain in game action, which can not only result in concussion, but catastrophic neck and spine injuries - is challenging, but clearly not impossible.

Psychologist Harry Harlow conducted a number of controversial experiments on social isolation in rhesus monkeys which demonstrated the devastating effects of disrupting early attachments.

There are reasons to believe that ethnicity might effect vote choice, but there are a number of confounding variables which are difficult to control for:

Eventually, along the legalisation process, Iran's high number of death sentences, which is a principle side - effect of the country's war on drugs, would be almost nullified.

Shadow home secretary Yvette Cooper said Ms May had given MPs an unbalanced account of the report, which did not include the passages on ministerial responsibility or the effect of reduced staff numbers on the UK Border Force.

Gennaro and other opponents of fracking in New York have raised the issue's visibility in part by pointing to the disastrous effects the practice has had in a number of Western states that have allowed it, and in Pennsylvania, which shares the same source of gas as New York State, the Marcellus Shale formation, which runs from the Southern Tier to West Virginia, and west to part of Ohio.

A statement signed by the Head of Public Relations and Communications said, «With effect from 1st June, 2016, GWCL meter readers will be capturing customer consumption data with a hand - held android device equipped with a software, which already has customers» data comprising the following: customer name, customer phone number, customer's last captured consumption data, customer's geographical location and other relevant information».

The most recent overall increase in the size of the House, which came into effect at the 1984 election, increased the number of members from 125 to 148.