Unlike sperm cells, which are replenished throughout a man's lifetime, women have a finite
number of egg cells.
Yet only a small
number of egg cells are produced by the female body, so they are the limiting factor in many aspects of reproductive science.
Not exact matches
The initial single
cell of the
egg undergoes a
number of cell divisions to produce a mass
of similar
cells.
The «Puffle» cones are crafted from gai daan jai, which translates to «little
eggs,» — a fluffy, eggy waffle with semi-spherical
cells — with a
number of English interpretations (bubble waffles, eggettes, and Hong Kong cakes, just to name a few).
If you are having a girl, her ovaries now contain primitive
egg cells; about six million (approximately six times the
number she'll have at the time
of birth).
Asexual whiptails have a special trick for making spermless reproduction work: The
egg cells in other animals first double their choromosomes once and then divide twice, leaving them as haploid
cells, with half the normal
number of genetic material.
But the whiptails»
egg cells first double their chromosomes twice and then divide twice, leaving them with the normal
number of chromosomes and rendering a sperm
cell unnecessary.
Combining an
egg's genetic leftovers with donor
cells may be a way to double the
number of eggs available for IVF in women whose ovarian reserve is running low
They made these clones by a process called automatic parthenogenesis: The
egg is formed normally (with half the species» usual
number of chromosomes), then fertilized by the «polar body,» a
cell that is created during oogenesis and contains the same gene copies as the
egg, resulting in the shark having half the genetic variation
of its mother.
While BPA did not affect the
number of eggs retrieved, «it's worrisome that any compound could decrease productivity
of the ovarian
cells,» said Dr. Fred Licciardi, a specialist in reproductive medicine and surgery at the New York University Fertility Center who was not involved in the study.
During the formation
of eggs and sperm, the
cell's chromosomes must pair up and part in an elaborate sequence that results in sex
cells with exactly half the
number of chromosomes as the parent
cell.
However, this method raises the following problem: in every nuclear transfer, a small
number of defective mitochondria are transferred into the healthy
egg cell.
The researchers then confirmed that the
number of singly paired chromosomes — also called univalents — was higher in older mouse and even human
egg cells, indicating that age - related segregation errors could be tracked back to increased
numbers of prematurely separated chromosome pairs.
But the discovery
of vast
numbers of immature
eggs dying in the ovaries
of mice led Tilly's team to find what they claim are hidden ovarian stem
cells that can sprout new
eggs to replace
This made the resulting
egg cells more likely to have the wrong
number of chromosomes (Current Biology, doi.org/b46s).
They found that women with the lowest
number of eggs also had the shortest telomeres — the chromosome caps that wear away as
cells age — in their white blood
cells.
Some research suggests a small
number of stem
cells continue making new
eggs throughout a woman's life, but we don't know much about these yet.
When a sperm
cell meets an
egg cell (the oocyte), it burrows through the thick outer rind surrounding the
egg (the zona pellucida), enters the internal cytoplasm
of the
egg (the ooplasm), and locomotes its male DNA — half
of the typical
number of chromosomes — to the female half within about three to four hours.
But he adds that if human parthenotes routinely contain as many genetic mismatches as the Korean
cells, the
number of eggs needed to create such a bank could be prohibitively large.
Because the
egg - donor mother also supplies to each embryo a small
number of mitochondria — tiny energy factories within
cells that have some
of their own genetic material — this approach even affords lesbian couples an approximation
of sexual reproduction.
«The use
of nonhuman oocytes for SCNT is currently the only ethically justifiable option given the large
numbers of eggs required to derive cloned human stem
cell lines,» he said.
SCNT requires a large
number of eggs and produces very few stem
cell lines.
After an extended
number of cell divisions, random segregation
of mitochondria may lead to
cells containing a majority
of mitochondria from the donor
egg.
Human tissues exposed to either drug for one week in a dish had reduced
numbers of cells that give rise to sperm and
eggs, called germ
cells, the study found.