Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and
future negotiations with commercial and
government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other
government action that could have the effect
of lowering prices or reducing the
number of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's
future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
These statements may involve a
number of risks, uncertainties and other factors that could cause actual results to differ materially, including the performance
of financial markets, the investment performance
of NexPoint Advisors, L.P.'s or Highland Capital Management L.P.'s sponsored investment products, general economic conditions,
future acquisitions, competitive conditions and
government regulations, including changes in tax laws.
Certain statements in this press release regarding the Company's expected
future shipment volumes, gross margins, and its ability to receive the required
government approvals for the sale
of six solar power projects in California, are forward - looking statements that involve a
number of risks and uncertainties that could cause actual results to differ materially.
The Public Policy Forum's report on the
future of journalism and democracy was designed to convince the Liberal
government to enact a
number of changes to help Canada's media industry, including amending the Income Tax Act and the Copyright Act to provide new streams
of revenue for the media.
In this particular instance it is not very difficult to imagine scenarios in the not - too - distant
future in which there might occur resurgences
of socialist policies and ideals: the failure
of neo-capitalist regimes in developing societies and / or the formerly Communist countries in Europe to achieve economic take - off; the insight granted to sundry dictators and despots that, while socialism invariably immiserates the masses, it is a very good recipe for enriching those who claim to hold power as the vanguard
of the masses; the «creeping socialism» (still an aptly descriptive term) brought on by massive
government intervention in the economy in the name
of some societal good, e.g., there could be an environmentalist road to socialism, or a feminist one, or one constructed (perhaps inadvertently) with some other building blocks
of politically managed regulations and entitlements; or, last but not least, the actual restoration
of socialism, by coup or by voting, in a
number of countries, beginning with Russia.
Sydney's Food
Futures (2015 - 2016) is a collaborative research project being undertaken by the Institute for Sustainable
Futures at the University
of Technology Sydney, in conjunction with a
number of government and industry partners (see About the project).
«The
number of women saying they feel pessimistic about their
future in the profession and the
number saying their priority is to leave teaching must give employers and
Government pause for thought about the urgency
of the need to create a teaching profession which genuinely values and supports all women teachers.
And to make matters worse, the
government has given no assurance that the
number of future closures will not be higher than the 2,500 they announced.
«With the
Government unwilling to include a ban on the use
of stray cats and dogs in the update
of the Animals (Scientific Procedures) Act, the worry is that the
number of experiments using animals may increase further in
future years.»
They talked about a
number of issues facing the territory, including the economic impact his people have on the state, the
future of gaming in New York, and the ongoing dispute between the nation and state
government over the collection
of cigarette taxes.
She spoke to Andrew Neil about
future devolved powers to the Scottish
government, the Barnett Formula, and the rising
number of leading women in Scottish politics.
Mr Osborne set out a
number of policies for a
future Tory
government, including a freeze on fuel duty and a requirement for the long - term unemployed to work for their benefits.
Question topics included the estimated time for completion
of all
of the Sandy recovery home rebuilding, the implementation
of new flood maps, whether de Blasio's reported
future endorsement
of Hillary Clinton is tied to a longterm need for federal
government assistance, whether in Secretary Castro's view the City could do better on any element
of Sandy recovery efforts, communicating an increased sense
of urgency to City agencies, significant variations in the reported
number of Build It Back applicants, how the City will continue its increased rate
of repairs, details on the construction firms used in the program and praise for developer Gerry Romski.
Similarly, this exercise will enable us to collect biometrics
of beneficiaries and to create Bank Verification
Numbers to enable
government to make
future payments through their individual bank accounts.»
Evidence from John Curtice at Strathclyde University shows that the decline in the
number of marginal seats and the reduced share
of the vote for the two main parties means coalition
government is now much more likely in the
future.
Seventeen states and the District
of Columbia have rates higher than that mandated by the federal
government, and a
number of states have indexed
future increases to the cost
of living.
In its 2017 release, the sixth Kreston Academies Benchmark report, one
of the leading reports on the health
of the sector, raises concerns about the
future viability
of a
number of academy schools, as the
government seeks to encourage even more schools to become academies.
«The
number of women saying they feel pessimistic about their
future in the profession and the
number saying their priority is to leave teaching must give employers and
government pause for thought about the urgency
of the need to create a teaching profession which genuinely values and supports all women teachers.
However, the
government's introduction
of student loan reimbursement programme for science and Modern Foreign Languages (MFL) teachers may help to reduce the
number of teachers leaving in the
future.
Moreover, the
number entering initial teacher training (ITT) programmes has not met
Government targets, which are based on forecasts
of likely
future demand for teachers, for several years.
I am fairly good with
numbers and have a decent investment understanding and I still found it a lot
of work and confusing, so I think the
government isn't succeeding in getting the money to families who could really use it in the
future.
Regarding how the UK authorities plan to remedy this situation in the
future, the SLC representative said this: «
Government's repayment strategy will boost SLC's capability to trace noncompliant borrowers, pursue and recover outstanding student loan debt, and it also includes the provision for the potential use
of a
number of sanctions.»
Around 7,000 strays had to be found new homes last year via Cats Protection because they had no form
of identification so the charity is urging the
Government to change the law to ensure this
number is reduced in the
future.
-- A growing
number of affordable, long - range electric vehicles coming on the market — Ongoing policy - making commitment to those vehicles, even from a post-Brexit conservative UK
government (the
future is a little less certain on this side
of the pond)-- Low cost, large - scale renewables and wide - spread energy storage — A wider range
of non-car transportation options, including affordable, high - quality e-bikes — Internal combustion engines shall henceforth forever be known as the Suck - Squeeze - Bang - Fart engine
Besides the «consensus» about AGW there is also a consensus about over population, the
number of inhabitants our planet could endure at a sustainable level, a consensus about
future religions, a consensus about
future government and how to engage a transformation process.
«If the Liberian
government is serious about turning the page on the past and using natural resources to improve the lives
of its citizens rather than enrich the corrupt, enforcing laws and prosecuting
government officials and companies who violate them should be its
number one priority; this could make or break the country's
future.»
This is so because in addition to the theological reasons given by Pope Francis recently: (a) it is a problem mostly caused by some nations and people emitting high - levels
of greenhouse gases (ghg) in one part
of the world who are harming or threatening tens
of millions
of living people and countless
numbers of future generations throughout the world who include some
of the world's poorest people who have done little to cause the problem, (b) the harms to many
of the world's most vulnerable victims
of climate change are potentially catastrophic, (c) many people most at risk from climate change often can't protect themselves by petitioning their
governments; their best hope is that those causing the problem will see that justice requires them to greatly lower their ghg emissions, (d) to protect the world's most vulnerable people nations must limit their ghg emissions to levels that constitute their fair share
of safe global emissions, and, (e) climate change is preventing some people from enjoying the most basic human rights including rights to life and security among others.
This is so because: (a) it is a problem mostly caused by some nations and people emitting high - levels
of greenhouse gases (ghg) in one part
of the world who are harming or threatening tens
of millions
of living people and countless
numbers of future generations throughout the world who include some
of the world's poorest people who have done little to cause the problem, (b) the harms to many
of the world's most vulnerable victims
of climate change are potentially catastrophic, (c) many people most at risk from climate change often can't protect themselves by petitioning their
governments; their best hope is that those causing the problem will see that justice requires them to greatly lower their ghg emissions, (d) to protect the world's most vulnerable people nations must limit their ghg emissions to levels that constitute their fair share
of safe global emissions, and, (e) climate change is preventing some people from enjoying the most basic human rights including rights to life and security among others.
These features include: (a) it is a problem caused by some nations and people emitting high - levels
of ghgs in one part
of the world who are harming or threatening tens
of millions
of living people and countless
numbers of future generations throughout the world who include some
of the world's poorest people and who have done little to cause the problem, (b) the harms to many
of the world's most vulnerable victims
of climate change are potentially catastrophic, (c) many people most at risk from climate change often can't protect themselves by petitioning their
governments; their best hope is that those causing the problem will see that justice requires them to greatly lower their ghg emissions, and, (d) to protect the world's most vulnerable people, nations must act quickly to limit their ghg emissions to levels that constitute their fair share
of safe global emissions.
«Eschewing the piecemeal, poll - tested «all
of the above» energy strategies
of the past, O'Malley has made clear that he will use the full force
of his executive power to make the transition to a clean energy
future the
number one priority
of our federal
government,» Smith wrote.
Implementation
of favorable
government regulations such as the Hydropower Regulatory Efficiency Act and Small Conduit Hydropower Development and Rural Jobs in the U.S. and growing
number of funding programs pertaining to the renewable energy sector in developed countries such as Italy and Canada are some
of the factors which are expected to present
future growth opportunities.
It includes a growing
number of initiatives at the international and European level, from research networks
of data providers, operational services, impact assessments, to coordination
of government initiatives and provision
of policy - relevant recommendations; all provided on a wide range
of timescales, from few years to decades and more, referring to the past, the present and the near to far
future.
The success
of a climate - based Charter challenge will depend on a
number of factors, including who would bring the case, what
government conduct would be challenged and whether the courts would accept the causal link between the present and
future harms
of climate change and the
government's management
of GHG emissions.
A growing
number of national and sub-national
governments turn to carbon markets to meet their
future GHG emission goals, but while a large
number of developing nations are interested in selling carbon credits in an international market there is little interest in buying.
The image that emerges here is not one
of a technology that receives a gentle nudge to help it replace the outdated but culturally entrenched technology we currently use, but rather,
of a
number of private companies that compete for a variety
of subsidies handed out by
governments who seek to plan in advance how
future technology will have to look, willfully ignorant
of whatever effect physical limits might have on determining which technologies are economically viable to sustain and which aren't.
However, as a
number of reporters warned Kinder Morgan and the industry as a whole, SLAPPs can, and do, backfire, creating the ground for
future more dedicated social movements, better prepared and financed to take on
government, corporations and industry.
While many
of the twelve danger signs I outlined in my initial paper continue to be
of concern, my
number 11: «Massive increases in
government debt at all levels» continues to be a predominant issue (both in the U.S. and in every Canadian province) and one that you need to be fully aware
of as you plan for your firm's
future trajectory.
Either the law society finds ways to reduce the
number of eligible licensees to match the available articling opportunities (and I sure can't think
of any that won't invite
government scrutiny), or it drops the articling requirement and creates a potentially major threat to the ability
of future generations
of new lawyers to competently practise law upon their admission to the Bar.
Recognizing that
government can't pay the bill for long - term care, federal and a growing
number of state tax codes now offer tax incentives to encourage Americans to take personal responsibility for their
future long - term care needs.
There are a
number of levels at which Indigenous communities have been involved in the
governments» compilation
of responses, and could be involved in the
future implementation
of those responses.