Sentences with phrase «number of genes within»
In - silico analysis can yield important insights into this aspect, facilitating comparison of two or more classes of genes comprising of a large number of genes within each group.
https://bmcbioinformatics.biomedcentral.com/ Not exact matches
Not long after the HD gene was isolated, studies led by MacDonald, also a co-author of the current investigation, found that a variation in the number of CAG trinucleotide repeats within the HD gene, which codes for a protein called huntingtin, is the primary determinant of the age at which HD symptoms appear, with a greater number of CAG repeats associated with an earlier symptom onset.
PE: To progress toward cancer, you need a few specific genes to be mutated, within a limited number of cell divisions, to cause the cells to divide uncontrollably.
They found additional changes to the small number of genes carried within the mitochondria, the cell's powerhouses.
«The use of whole genome sequencing and the sheer number of samples we collected gave us a detailed picture of how the var gene repertoire changes continuously within red blood cells.»
So, if a gene lies within a gene - dense, low - recombination region, then this means that a much larger number of progeny from crosses must be examined to find those that derive from rare recombinational events that separate the desired new allele from undesirable forms of neighboring genes.
And instead of just several types of brick, it turned out that there were dozens of smaller variations within each type of brick, represented by the many slightly differing copy numbers in the gene.
However, such CRISPR screens are sensitive to a phenomenon called the copy number effect, where genes that have been repeatedly duplicated within a cell (as commonly happens in cancer cells) can be flagged as essential regardless of whether they are or not.
We also identified a «meditation effect» within the regular meditator group, characterized by a distinct network of genes with cellular functions that may be relevant to healthy aging, and this network was associated with increased expression of a number of telomere maintenance pathway genes and an increase in measured telomerase enzymatic activity.
Consistent with the variation in size we also found a heterogeneous number of genes contained within each region (ranging from 1 — 31).
A number of Invivoscribe LymphoTrack Assays, formatted for use on both the Illumina MiSeq ® and Thermo Fisher Ion PGM ™ platforms, were designed to detect somatic gene rearrangements within the antigen receptor loci.
The number of regulated genes is shown within the circle.