Not exact matches
Using a flexible mouse model, her team set out to determine whether anything could be
done to restore memory «after a significant
number of neurons are lost in the brain.»
«While environmental enrichment didn't seem to significantly influence the
number of neurons [that were damaged],» explains Tsai, «it
does induce the growth
of dendrites and high
numbers of synapses,» both
of which are neuronal structures that underlie how brain cells communicate with one another.
Instead mice injected with stem cells developed a far greater
number of synapses, or connections between
neurons, at the damaged site than control mice
did.
Given that there are a
number of different types
of neurons in the cerebral cortex and that there are many areas where the
neurons do things other than help with memory, you can see how one billion is a conservative estimate I hoped would be useful for understanding the storage capacity
of the human brain.
So it turns out that Karl Lashley's belief in memory as existing in a distributed network is still alive and well; Silva and Josselyn have not overturned it, only supplemented it, showing that some parts
of some memories
do exist in a discrete
number of neurons.
«Although running induces both substantial changes in
number and morphology
of young
neurons as well as significant changes in learning behavior, this
does not prove a causal relationship,» noted Professor Bischofberger, «Nevertheless, our results, together with previous findings, suggest that the enhanced pattern separation during memory testing is most likely mediated via running - induced increase in adult neurogenesis.»
«If function is localized, with small
numbers of neurons bunched together
doing similar things, that's consistent with sparse coding, high selectivity, and low population spiking rates.
The MRI scans showed that obese subjects with binge eating disorder have lower grey matter volumes — a measure
of the
number of neurons — in the orbitofrontal cortex and striatum
of the brain compared to those who
do not binge eat; these brain regions are involved in keeping track
of goals and rewards.
Overstreet - Wadiche and UAB colleagues posed a basic question: Since the
number of neurons in the dentate gyrus increases by neurogenesis while the
number of neurons in the cortex remains the same,
does the brain create additional synapses from the cortical
neurons to the new granule cells, or
do some cortical
neurons transfer their connections from mature granule cells to the new granule cells?
It has to
do with their brains, specifically the
number of neurons in their cerebral cortex: the «little gray cells» associated with thinking, planning and complex behavior — all considered hallmarks
of intelligence.
The
number of learning trials I
did measured how often the
neuron needed to be trained until it reached 90 % correct responses.»
NGF
does not increase the
number of neurons in the sympathetic ganglia by enhancing their multiplication.
Because it is the largest primate brain, it
does have one distinctive feature: It has the highest
number of cortical
neurons of any primate.
But the
number of neurons at a time with which microelectrode arrays can interface must be increased several-fold while making sure the scale - up
does not cause damage to brain tissue.
For instance, when a person sees a clock, only a small
number of neurons become active, enough to
do pattern matching that draws upon the brain's memory
of a clock and compares it with the object's basic features — its round shape, the presence
of numbers — to draw a conclusion that this thing is a clock.
While Htt null KO mice
do not survive to birth (Duyao et al., 1995; Nasir et al., 1995; Zeitlin et al., 1995), mice expressing a 50 % reduction
of endogenous htt levels reveal cognitive and motor deficits (Nasir et al., 1995) and significant decreases in the
number of neurons in globus pallidus and subthalamic nucleus (O'Kusky et al., 1999).
«Composed
of roughly 100 billion
neurons... the human brain is so complex that scientists have not yet found a way to record the activity
of more than a small
number of neurons at once, an in most cases that is
done invasively with physical probes.»
Exercise
did not increase progranulin protein levels in frontal cortex (B), thalamus (C), or hippocampus (D), despite producing the expected increase in the
number of doublecortin - positive
neurons in the dentate gyrus (E, ** p < 0.01).
Quantification
of relative amounts
of neurons expressing ZENK was
done by estimating the total
number of neurons on Nissl - stained sections in defined areas
of Cluster N.
INX - 4:: GFP
does not appear to be expressed in
neurons implicated in locomotion, but is expressed in a
number of ciliated
neurons, pharyngeal m1 muscle cells, and the RIP
neurons that form gap junctions with pharyngeal I1
neurons (Figure 5E).
However, in the absence
of lithium, occurrence
of neuronogenesis in the spinal cord
of G93A mice is uncertain, and, when occurring (27), it
does not produce a net increase in
neuron number compared with controls.
Ultimately, researchers determined carnivores don't necessarily have more
neurons than their prey and that brain size
does not correlate with the
number of neurons.