Sentences with phrase «number of patient dna»
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The Stanford team found, however, that mitochondrial DNA levels were significantly elevated in plasma samples from a small number of HD patients.
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The MGH team has assembled a large number of DNA samples from HD patients who contributed them for research to the Massachusetts HD Center Without Walls and through collaboration with the Huntington Study Group.
After analyzing both scans together for DNA variants associated with differences between when each patient's movement - associated symptoms first appeared and when they would have been expected based on the number of CAG repeats, MGH CHGR investigator and lead author Jong - Min Lee, PhD, identified two locations on chromosome 15 where variants were significantly associated with either early or late symptom onset.
When they sequenced the iPS cell lines, they found higher numbers of mitochondrial DNA mutations, particularly in cells from patients older than 60.
We've analyzed a number of patients» DNA to look for the mutation in the gene we [found].
In this study, researchers assessed the outcomes of 280 prostate cancer (Cap) patients, and reviewed the DNA «fingerprints» of each patient's tumor (using the patient's initial diagnostic core biopsy) to determine if gene copy number alterations (CNAs), or breaks in CFSs, were related to a less positive response to treatment.
First author Baoshan Xu, Ph.D., a former postdoctoral research associate in the Gerton Lab now starting his own lab at Sun Yat - sen University in China, worked with Hua Li, Ph.D., to use computational methods to count the number of copies of ribosomal DNA in normal and cancer cells of 162 patients from the eight projects.
«Most patients who had low copy numbers of mitochondrial DNA have a poordisease prognosis,» Guha said.
Dr. Rudolph's group is developing mouse lines that carry mutations found in patients with schizophrenia — specifically copy number variations, in which segments of DNA are either duplicated or deleted.
DNA copy - number analysis of cfDNA of patient 2 identified single copy loss at the BRCA2 locus (Supplementary Fig.