Because many diseases are exceedingly rare, it is unlikely that one investigator will be able to collect a sufficient
number of patient samples to reliably pinpoint disease genes.
Not exact matches
The researchers are analyzing more
patient samples looking for additional cases
of multiple copy
number variants to continue their investigation
of what may trigger this rare phenomenon.
The Stanford team found, however, that mitochondrial DNA levels were significantly elevated in plasma
samples from a small
number of HD
patients.
The MGH team has assembled a large
number of DNA
samples from HD
patients who contributed them for research to the Massachusetts HD Center Without Walls and through collaboration with the Huntington Study Group.
In addition, the researchers looked at brain
samples of deceased
patients with MS and found increased
numbers of GM - CSF - producing cells in comparison to normal brain
samples.
This is due to the fact, that the
number of pathogens in a
patients sample is too small to conduct tests.
Researchers have found that just five strains are overwhelmingly the culprits in more than 3000
samples of resistant S. aureus collected from
patients around the world; the small
number suggests that relatively few strains can easily develop resistance to antibiotics, allowing scientists to focus on these few and determine what makes them so virulent.
They
sampled fluid from 20
patients with a long history
of schizophrenia, 35 individuals that had recently developed the disorder, and a
number of different control groups.
The assay was implemented in five countries and tested using a large
number of clinical
samples from travelers and
patients living in areas with a high level
of exposure to Zika virus and other flaviviruses.
«There are a
number of possible explanations for the relationship found between food allergy diagnosis and increased social anxiety issues in this
sample of pediatric
patients,» noted Dr. Goodwin.
They found strains
of Streptococcus in throat
samples from a
number of patients but eliminated it as the cause
of death after finding the same strains in
samples from children with other symptoms.
The start
of each project will depend on a
number of factors, including the strategic selection
of specific diseases and the availability
of patient samples with appropriate informed consent.
The total
number of patient and control
samples analyzed in the study was 3430 and 2675, respectively.
But Reid cautioned that the small
patient sample and the small
number of genes analyzed means that the results should be considered preliminary until a larger study is done.
Using this technology, we screened 31
patient samples across an array containing a total
of 162 exons for five disease genes and detected copy -
number changes, ranging from whole - gene deletions and duplications to single - exon deletions and duplications, in 100 %
of the cases.
Additionally, we clarified the role
of iNKT cells in human asthma by carefully enumerating cell
numbers in airway
samples from asthma and COPD
patients.
«To confirm whether
patients have a bacterial infection
of the respiratory tract, doctors currently have to take a
number of different
samples (blood and septum) and even chest X-rays in the case
of pneumonia,» said project coordinator Kejing Ying in a statement.
The frequency - based approach requires a significant
number of samples, and likely favors driver mutations that are common across a
patient population.
There are now a
number of studies about tobacco and alcohol increasing spontaneous abortions but one must be careful to distinguish studies whose
patient population has a confirmed pregnancy (seven weeks after last menses) from those «early pregnancy loss» studies using daily urine
samples tested for human chorionic gonadotropin (hCG) to detect pregnancy via hCG rise in the second week after ovulation.
Lab Technician — ABO Laboratories — May 2012 — Present • Execute a variety
of laboratory assays and tests in accordance with established procedures, policies, and regulations; ensure
samples are properly labeled and stored • Study blood
samples for transfusions and record the blood group,
number of cells, blood type, cell morphology, and other blood type compatibility • Perform procedural and instrument calibrations, document all quality control activities, and perform regular equipment maintenance • Identify problems that may negatively affect test results or performance; correct issues immediately and properly notify supervisor • Maintain meticulous records and demonstrate that the testing
of samples is done in the same manner as
patient specimens; promote cost - effective testing practices and reduce waste by 10 percent
The
sample section also incorporates metrics by including the
number of patients treated in each clinical experience.
We entered the
number of patients and control group members, mean age, percentage
of girls and
of members
of ethnic minorities, the country
of data collection, year
of publication, type
of illness, duration
of illness, the
sampling procedure (1 = probability
samples, 0 = convenience
samples), the use
of a control group (0 = yes, 1 = comparison with test norms), equivalence
of patients and control group (1 = yes, 2 = not tested, 3 = no), the rater
of depressive symptoms (1 = child, 2 = parent, 3 = teacher, 4 = clinician), the measurement
of the variables, and the standardized size
of between - group differences in depressive symptoms.
In the current study with a
sample of chronically depressed men and women, rates
of physical and psychological victimization were similar to rates reported in a
number of general community
samples during a similar time period (Jose and O'Leary 2009; Schafer et al. 1998) and to rates reported with a
sample of unipolar and bipolar depressed
patients (Dienemann et al. 2000).
Furthermore, not enough data was available to include the comparison
of secure vs. insecure attachment representations, because
of the low
number of securely attached
patients in the current
sample.