Sentences with phrase «number of proteins involved»

PKC regulates activation and transcription of a large number of proteins involved in the inflammatory process, including the production of IL - 1b, expression of COX, and formation of O2 - by NADPH oxidase.

Number of proteins involved in a particular cancer, as well as drugs and compounds acting on cancer - related and their first neighbour proteins.

The researchers measured the levels of a number of proteins involved in memory and learning and found that levels of the protein deltaFosB strikingly increase in the hippocampus of Alzheimer's disease mice that had seizures.

Not exact matches

The silver lining, says Richard Salmon, a retired neurologist who wrote an editorial accompanying the research, is that recent research shows that the vCJD prion behaves much like the pathological proteins behind a number of other diseases involving brain degeneration, including Alzheimer's and Parkinson's diseases.

If animal tests go well, the next trials will be with humans, a process that involves three stages — one for safety, the next to see if the protein kills cancer in a limited number of people, and the last to turn it loose in a large group.

In particular, the protein enhances the expression of a well - characterized oncogene called MYC, which in turn regulates a large number of genes involved in cell proliferation.

To narrow down the number of chemical compounds that could be potential drug candidates, scientists utilize computer models that can predict how a particular chemical compound might interact with a biological target of interest — for example, a key protein that might be involved with a disease process.

This gene, along with a number of other genes encoding proteins involved in nickel homeostasis, has been acquired a long time ago by the bacterium via horizontal gene transfer.

«Our work suggests that the apparent complexity of protein networks is deceiving, and that a circuit involving a small number of proteins might control each cellular function,» said senior author Shohei Koide, PhD, professor of biochemistry & molecular biophysics at the University of Chicago.

Collagen, a structural protein often involved in scarring and wound healing, is emerging as an important factor in a number of other diseases, Eliceiri says.

CXCR4 is a G - protein - coupled receptor involved in a number of physiological processes in the hematopoietic and immune systems.

Their activity increases in response to heat, toxins, and various other forms of cellular stress, and dialing up the activity of heat shock proteins is involved in a number of methods demonstrated to slow aging in laboratory animals.

The proteins and pathways involved in suturing a fractured genome back together are now the focus of a number of studies.

The mechanism for improvement may be a synergistic effect involving a number of non-denatured proteins.

Activation of the insulin receptor leads to sequential activation of a number of protein and lipid kinases, including the serine / threonine kinases Akt1 and Akt2, which not only stimulate mTOR and thus downregulate autophagic protein catabolism (and thus cysteine supplies), but elicit phosphorylation (inhibition) of FOXO1, a transcription factor that induces expression of proteins involved in both of the proteolysis recycling pathways: the autophagic / lysosomal pathway and the ubiquitin - proteasomal pathway.

The reason involves the surprising number of roles that protein plays in our body.