Sentences with phrase «number of tumors»

There are billions of red blood cells, tens of thousands of white blood cells, and, perhaps, only a small number of tumor cells floating among them.

Although changes in treatment methodology still have to be studied, Dr. Cripe believes it may be that the timing of various treatments is what matters, and that perhaps initially suppressing immunity could allow the virus to infect a large number of tumor cells before relieving the immunosuppression to allow the body's own T cells to fight off the tumor.

In other experiments, the laboratory mice with wild microbiomes had better outcomes in the face of induced colorectal tumors, whereas the other mice had a greater number of tumors and more severe disease.

It is defined as a decrease of ≥ 50 % in the total tumor size and / or total number of tumors since the start of the trial.

Bone marrow biopsies often produce limited numbers of tumor cells to test — as few as 50,000 tumor cells in this study — but for this technique that is enough to test many different drugs and drug combinations.

Crucial to this approach is careful patient selection, distinguishing between patients who have a treatable number of tumors and those who have widespread metastasis, including multiple tumors too small to detect.

Re-directed Autologous T cell Therapy for drug resistant or refractory CD20 + B cell lymphoma Overview: In this approach, immune cells (known as T cells) are taken from the peripheral blood, genetically modified in the laboratory to express a receptor that recognizes B cells, and then expanded to produce large numbers of tumor specific T cells outside -LSB-...]

«Even when an entire tumor has been removed, it is common for a small number of tumor cells to remain behind.

Could this explain the greater number of tumors and the disproportionate incidence of breast cancer in the upper outer quadrant of the breast near the armpit?

It is defined as an increase of ≥ 25 % in total tumor size and / or number of tumors since the start of the trial.

What's the best way to give it to minimize the number of tumor cells for the longest amount of time?»»

The conversion improves the cells» tumor - forming ability, cutting the number of tumor cells required to form a carcinoma from one million to just 10,000, the researchers say.

Though this approach kills the majority of tumor cells, it often spares a small number of tumor - initiating cells (TICs) that subsequently give rise to new tumors.

Giving the mice antibiotics helped gemcitabine kill tumor cells, increasing the number of tumor cells going through a type of cell death called apoptosis from about 15 percent to 60 percent or more.

For the animal study, the researchers separated 52 mice with colon cancer tumors into three groups, including a control group and groups that were fed either the grape compounds or sulindac, an anti-inflammatory drug, which was chosen because a previous study showed it significantly reduced the number of tumors in humans.

For several months, Dr. Johnson and his team gave sulforaphane to mice predisposed to oral cancer and found that it significantly reduced the incidence and number of tumors.

They discovered that the number of tumor suppressor genes or oncogenes in a chromosome correlated with how often the whole chromosome or part of the chromosome was deleted or duplicated in cancers.

AMD3100, alone or in combination, reduced the number of tumor - infiltrating Treg cells and increased the proportion of CD8 T cells.

T cells are collected from a patient and grown in the lab to increase the number of tumor - killing T cells..

Likewise, TGF - β production has been reported from a number of tumors, contributing to immune evasion.

«Giving a baby a dose of Viagra can reduce the number of tumors in these animals by half,» says Browning.

CFE was calculated by dividing the number of tumor spheres formed by the original number of single cells seeded and is expressed as a percentage.

Adams found that the number of tumor infiltrating lymphocytes (TILs) correlated with outcome: the more TILs, the longer the survival.

Surprisingly, forced expression of let - 7 also reduced the number of tumors formed in the mouse and reduced their metastases.

Association and prognostic significance of BRCA1 / 2 - mutation status with neoantigen load, number of tumor - infiltrating lymphocytes and expression of PD - 1 / PD - L1 in high grade serous ovarian cancer.

And another one in rodents with lung cancer published in Science Translational Medicine in 2014 found that normal doses of vitamin E and smaller doses of acetylcysteine, an antioxidant supplement, appeared to lead to a three-fold increase in the number of tumors and caused them to be more aggressive.