Sentences with phrase «number of variants in»

Peugeot has reduced the number of variants in its 308 model range, pricing for which now starts more than $ 8000 higher, by almost two - thirds to just six.

With this addition, the total number of variants in the 3 GT lineup goes up to three - one diesel and two petrol Read Full News

The research shows that children need to inherit a certain number of variants in order to develop autism.

and bart shouldn't even be included because of his disingenuous book about the variants of the BIble... (he never really gets down to the explicit details of what they are... thus misleading people into thinking the Bible is full of errors - for example... a verse may say «Jesus said to give all your possessions» whereas a VARIANT says «And HE says, give all your possesssions») an extremely low number of variants in the Bibel even change a thing...

Not exact matches

The first step in taming this beast is to find out what's out there by Googling all variants of your name, your phone number, and your address.

Of these about one in three is a variant of some other saying in the collection so that the total number of different recognized sayings in his collection is under 3,00Of these about one in three is a variant of some other saying in the collection so that the total number of different recognized sayings in his collection is under 3,00of some other saying in the collection so that the total number of different recognized sayings in his collection is under 3,00of different recognized sayings in his collection is under 3,000.

At least in part to deal with such points, Eigen more recently pointed out that each biological genome is not a single sequence of bases on DNA (a unique «point in sequence space») but rather a fairly large number of variant sequences that have quite similar — even indistinguishable — biological functions.11 b, 11 c Most of these functionally similar sequences differ from the «wild - type» sequence in only one or a few locations, but some have fairly large discrepancies.

The liberation theologians also vary in the degree of their economic precision, though a number of their leaders have been substantially influenced by variants of Marxism.

The derived relations among regions which Werth singles out as implicated in Whitehead's derivation of the definitions of point and segment as geometric elements are four in number: inclusion, its two variants, and the relation of incidence.

Of course both of these have manifested in a number of variations and there exist plenty of more variants that may or may not have been trieOf course both of these have manifested in a number of variations and there exist plenty of more variants that may or may not have been trieof these have manifested in a number of variations and there exist plenty of more variants that may or may not have been trieof variations and there exist plenty of more variants that may or may not have been trieof more variants that may or may not have been tried.

The researchers looked at a type of genetic change called copy number variants, which refers to the number of copies of genes in human DNA.

In humans, there are three common variants, or alleles, of the APOE gene, numbered 2, 3 and 4.

«Copy number variants in human DNA can be compared to repeated or missing paragraphs or pages of text in a book,» said senior author Dr. James R. Lupski, Cullen Professor of Molecular and Human Genetics at Baylor.

In this rare phenomenon, the copy number variants are predominantly gains — duplications and triplications — rather than losses of genetic material, and are present in all the cells of the chilIn this rare phenomenon, the copy number variants are predominantly gains — duplications and triplications — rather than losses of genetic material, and are present in all the cells of the chilin all the cells of the child.

The researchers then examined a number of DNA variants in the protein production - control region of the bellwether gene in cell cultures.

SURVIVAL GEAR Some genetic variants may have allowed a small number of Tasmanian devils to withstand a deadly contagious facial tumor that has killed up to 95 percent of them in some locales.

As in every EVD outbreak, the 2014 EBOV variant carries a number of genetic changes distinct to this lineage; our data do not address whether these differences are related to the severity of the outbreak.

But these copy - number variants (CNVs) tend to be extremely rare, showing up in less than 1 % of children with autism.

They also plan to improve breeding programs by ensuring parental lines have the maximum number of repeats available in a given genotype, and to select for new variants with additional copies that may show superior resistance.

«We would anticipate that over time, a large number of functional variants [of HTR2B] will be identified, with a range of behavioural effects,» says David Goldman at the US National Institute on Alcohol Abuse and Alcoholism in Bethesda, Maryland, and head of the team that carried out the work.

To carry out the study, the team visualised a number of motors from different species of bacteria using a variant of a method called cryo - election microscopy, whose pioneers were awarded the Nobel Prize in Chemistry this year.

In this research, the group looked at two variants of miR - 21, a microRNA «oncomiR» known to target tumor suppressor genes and which is highly expressed in a number of cancers as well as other proliferative diseases such as psoriasiIn this research, the group looked at two variants of miR - 21, a microRNA «oncomiR» known to target tumor suppressor genes and which is highly expressed in a number of cancers as well as other proliferative diseases such as psoriasiin a number of cancers as well as other proliferative diseases such as psoriasis.

They have since identified new variants in a number of environments: hot springs, shallow marine sediments, rivers, even the permafrost.

As far as we're aware, it's the first study worldwide to show this in such detail, including a large number of genetic variants.»

Neanderthal genetic material is found in only small amounts in the genomes of modern humans because, after interbreeding, natural selection removed large numbers of weakly deleterious Neanderthal gene variants, according to a study by Ivan Juric and colleagues at the University of California, Davis, published November 8th, 2016 in PLOS Genetics.

Copy number variants are differences between individuals, populations or species in the number of times specific segments of DNA appear.

In contrast, copy number variants turned up in just 2 % of 47 families with multiple cases of apparently inherited autism, the team reports today in SciencIn contrast, copy number variants turned up in just 2 % of 47 families with multiple cases of apparently inherited autism, the team reports today in Sciencin just 2 % of 47 families with multiple cases of apparently inherited autism, the team reports today in Sciencin Science.

Results from the analysis confirmed previous findings of some copy number variants already associated with autism, but they also found a host of other genes (SHANK2, SYNGAP1, DLGAP2 and the X chromosome — linked DDX53 - PTCHD1 locus) in which mutations seem to be linked to autism.

Belsky and his colleagues calculated a genetic risk score for each of 880 individuals in the Dunedin cohort by summing the number of risk variants each of them carried.

Using a variety of techniques, the researchers scanned the genetic material for so - called copy number variants, in which relatively long stretches of DNA are lost or gained.

Where unaffected parents were sequenced as well as the child, researchers saw a 10-fold reduction in the number of variants needing clinical evaluation.

«One big problem we have is that tens of thousands of human genome variants and phenotypes are spread throughout a number of databases, each one with their own organization and nomenclature that aren't easily accessible,» said Julia Wang, an M.D. / Ph.D. candidate in the Medical Scientist Training Program at Baylor and a McNair Student Scholar in the Bellen lab, as well as first author on the publication.

Many of the variants involved in numerous types of cancer have been identified with genetic sequencing studies of large numbers of patients.

The combination of 20 different building blocks — amino acids — results in an enormous variety of theoretically possible protein variants; many more than the estimated number of stars in the universe.

Professor Samani, who is also Head of the Department of Cardiovascular Sciences at the University of Leicester and a Consultant Cardiologist at Leicester's Hospitals, added: «Height has a strong genetic determination and in the last few years a large number of genetic variants have been identified in our DNA that determines one's height.

If they're all firing at once, suddenly the number of combinations of protein variants in play is really massive.»

Given that two separate teams found evidence for the same variant in a large number of sick people, «one can be absolutely confident that this risk allele is real,» says McPherson.

Ehret, a research associate in Chakravarti's lab, crunched the numbers from all the study sites and found variants at 66 sites in the genome — 17 of them newly reported — that had statistically significant associations with blood pressure levels.

With its large sample size, this study had the power to find copy number variants with large effects that occur in more than 0.1 percent of schizophrenia cases.

The researchers also found that these copy number variants occurred more frequently in genes involved in the function of synapses, the connections between brain cells that transmit chemical messages.

The team found 50 individual variants of DENV - 1 in China, with 20 variants of DENV - 2, and lower numbers of variants of DENV - 3 and DENV - 4.

As it results in a smaller number of melatonin receptors, the risk variant of the gene can cause weaker natural melatonin signalling, one of the regulatory mechanisms in stabilising the circadian rhythm.

The number of car models, where at least one variant has a combined city / highway label fuel economy of at least 30 mpg, has grown from 46 models in MY 2012 to more than 70 models in MY 2017, and the number of car models with 40 mpg or higher has more than doubled (comprised of hybrid, electric (EV), plug - in hybrid electric (PHEV), and fuel cell vehicles (FCV)-RRB-.

Manou Sommen and colleagues report a study of a targeted resequencing panel for hearing loss was developed including 79 genes for nonsyndromic hearing loss (NSH) L and selected forms of syndromic hearing loss.They established a straightforward variant classification system to deal with the large number of variants encountered and showed that after GJB2, the most commonly mutated genes in a Western - European population are TMC1, MYO15A, and MYO7A.

Cardiomyopathy can be caused by a single mutation in any one of a number of genes, each one resulting in a slightly different variant of the disease.

In this study, the authors assessed the impact of SNPs, inherited copy number variants (CNVs), and acquired copy number alterations (CNAs) on the gene expression landscape.

In contrast to traditional genetic testing, which usually checks for variants in specific genes, high - throughput sequencing has the potential to reveal a number of secondary findings, i.e., genetic variants with medical relevance but not related to the condition that merited the tesIn contrast to traditional genetic testing, which usually checks for variants in specific genes, high - throughput sequencing has the potential to reveal a number of secondary findings, i.e., genetic variants with medical relevance but not related to the condition that merited the tesin specific genes, high - throughput sequencing has the potential to reveal a number of secondary findings, i.e., genetic variants with medical relevance but not related to the condition that merited the test.

Jacques Genest report in this scientific article that there are a bewildering number of scientific databases for genomics, DNA sequences, proteomics, and metabolomics that are open access or require institutional (for a fee) access available for researchers especially in Human variant databases.

This project indicated that not only a vast number of novel potentially functional variants in a total of 231 pharmacogenes was identified but also demonstrated the value of whole - genome sequencing for pharmacogenomic testing by capturing over 18,000 variants per individual in these pharmacogenes.

The first reports that gene - editing of bone marrow stem cells in monkeys infected with a variant of simian immunodeficiency virus (SIV) significantly reduces the number of dormant «viral reservoirs» that pose a risk of reactivation.