Sentences with phrase «number variants by»

DECIPHER aids clinical interpretation of these rare sequence and copy - number variants by providing tools for variant analysis and identification of other patients exhibiting similar genotype — phenotype characteristics.

Not exact matches

The first step in taming this beast is to find out what's out there by Googling all variants of your name, your phone number, and your address.

Anyway, this new book by Philip Wesley Comfort looks at a large number of the variant readings from the textual families, and briefly explains what the variations are, and what Comfort thinks is the best reading for a particular variant.

The liberation theologians also vary in the degree of their economic precision, though a number of their leaders have been substantially influenced by variants of Marxism.

The colours were stripped down in order to enhance visibility and brand recognition on shelf, while the enlarged 40, 45 and 50 numbers strategically increased differentiation to each variant by acting as sub-names.

Rather than creating each individual ad by hand, he could use his team's own technology to organize the ad elements (text, visuals, video, links), create a massive number of variants, and pass them over to Facebook as database files.

They also plan to improve breeding programs by ensuring parental lines have the maximum number of repeats available in a given genotype, and to select for new variants with additional copies that may show superior resistance.

Although these variants had revealed the main topology, we couldn't say much about the length of any branch — the number of variants shared by all of its descendants.

Breast cancer is caused by complex interactions between a large number of genetic variants and our environment.

Neanderthal genetic material is found in only small amounts in the genomes of modern humans because, after interbreeding, natural selection removed large numbers of weakly deleterious Neanderthal gene variants, according to a study by Ivan Juric and colleagues at the University of California, Davis, published November 8th, 2016 in PLOS Genetics.

Belsky and his colleagues calculated a genetic risk score for each of 880 individuals in the Dunedin cohort by summing the number of risk variants each of them carried.

Now, they've demonstrated that a single amino acid — known by its number along the protein chain, 139 — is the key to this prion protein variant adopting a «human - like» versus a «hamster - like» structure, while another amino acid, 112, governs the structural differences between the human and mouse versions of the protein.

Taking genetic data from 49 populations worldwide, Dediu and Ladd searched for correlations between 983 genetic variants, including ASPM - D and microcephalin - D, and 26 features of the languages spoken by the populations, including the number of consonants and the use of inflections or tones.

Through previous studies, many led by our team at the ICR, this brings the total number of genetic variants known to be associated with testicular cancer to 25.

Cardiomyopathy can be caused by a single mutation in any one of a number of genes, each one resulting in a slightly different variant of the disease.

An average CADD score was calculated for each individual by dividing the individual's cumulative CADD score by the number of their variant sites.

This project indicated that not only a vast number of novel potentially functional variants in a total of 231 pharmacogenes was identified but also demonstrated the value of whole - genome sequencing for pharmacogenomic testing by capturing over 18,000 variants per individual in these pharmacogenes.

The largest numbers of variants identified by genome - wide association are copy - number changes, which have a greater phenotypic effect than do single nucleotide polymorphisms.

These are called exon copy number variants (exon CNVs), and they are not easily picked up by standard DNA sequencing tests.

Another distinctive genetic feature of mucosal melanoma is its high rate of copy number and structural variants, demonstrated both by array - based comparative genomic hybridization and whole - genome sequencing.

Compounded by the fact that a single variant might affect multiple transcripts / genes, the number of observed human coding variants exceeds 22 million.

A number of green round bodies were observed, but without specific detection by molecular methods, we can not assert that these are morphological variants of B. burgdorferi.

A research team led by an award - winning genomicist at Western University has developed a new method for identifying mutations and prioritizing variants in breast and ovarian cancer genes, which will not only reduce the number of possible variants for doctors to investigate, but also increase the number of patients that are properly diagnosed.

Many patients suffering from Rare Disease harbour genomic variants (sequence variants or copy number variants) that by disrupting normal gene expression lead to disease.

Given a file of read alignments, VarScan detects sequence variants, combines them by position and type, and then computes the read counts, average base quality, and number of strands supporting each allele.

If the same technique works in humans, it could have big implications for curing a number of diseases caused by genetic variants.

By performing a meta - analysis of rare coding variants in whole - exome sequences from 4,133 schizophrenia cases and 9,274 controls, de novo mutations in 1,077 family trios, and copy number variants from 6,882 cases and 11,255 controls, we show that individuals with schizophrenia carry a significant burden of rare, damaging variants in 3,488 genes previously identified as having a near - complete depletion of loss - of - function variants.

By analyzing genome sequence data from human populations, including 1269 individuals from sub-Saharan Africa, we identify a diverse array of large copy number variants affecting the host invasion receptor genes GYPA and GYPB We find that a nearby association with severe malaria is explained by a complex structural rearrangement involving the loss of GYPB and gain of two GYPB - A hybrid genes, which encode a serologically distinct blood group antigen known as DantBy analyzing genome sequence data from human populations, including 1269 individuals from sub-Saharan Africa, we identify a diverse array of large copy number variants affecting the host invasion receptor genes GYPA and GYPB We find that a nearby association with severe malaria is explained by a complex structural rearrangement involving the loss of GYPB and gain of two GYPB - A hybrid genes, which encode a serologically distinct blood group antigen known as Dantby a complex structural rearrangement involving the loss of GYPB and gain of two GYPB - A hybrid genes, which encode a serologically distinct blood group antigen known as Dantu.

Mapping the changes in copy number to the phylogeny of these Y chromosomes previously established by the Project identified at least 20 mutational events, and investigation of flanking paralogous sequence variants showed that the mutations involved flanking sequences in 18 of these, and could extend over > 30 kb of DNA.

But the fact that the Elantra is a better variant of a long - in - the - tooth car does not endear us to it over the others here, despite the Elantra's bargain price and (by a hair) best - in - test EPA numbers.

Styles by Pinninfarina legend, Leonardo Fioravanti and built by Scaglietti, the timeless 365 BB is the rarest and lightest of all Berlinetta Boxer variants, with production numbers of 387 total, 88 right hand drive examples.

it should by the numbers have more performance oriented Variants than Chevy which also has Buick and Caddy to share in the performance.

The Volvo V90 Cross Country wagon gains a non-Cross Country variant that will be built in limited numbers by special order.

Peugeot has reduced the number of variants in its 308 model range, pricing for which now starts more than $ 8000 higher, by almost two - thirds to just six.

Stepping up to a V6 will add another $ 2,000 to that number and moving to Luxury trim pops both by about $ 3,000 while also introducing the first 3.0 - liter Twin - Turbo variant at roughly $ 64,500.

The Miix 700 isn't part - by - part configurable in a strict sense, but the company does offer a number of pre-configured variants, both from Lenovo's own Miix 700 product page, as well as other online outlets.

Unsurprisingly, the device is identified by the model number «SM - T395» which should correspond with the LTE - enabled variant, however, no other details about the product have been revealed by the regulatory agency.

Well, not all the handsets can be updated with this ROM, as only the unlocked international variant, model number N8010, is suitable with this tutorial meaning that if you try to install a similar device with the official Android 4.1.1 OS by following this guide, you will end up in bricking your tablet, or smartphone.

We can confirm that the tablet will come in Wi - Fi, 3G and LTE variants (model numbers SM - T800, SM - T801, and SM - T805) as was hinted in an earlier leak, and the display resolution will be 2560 × 1600 pixels (which is backed by the user agent string for the SM - T800 on Samsung's website), same as the recently released Galaxy NotePRO and TabPRO tablets.

Google's latest Android adoption numbers, fueled by a recently - changed methodology, are showing improvements in adoption of Android «Jelly Bean» variants.

Not inscribed Perspex, 13 7/8 x 16 1/8 x 15 3/4 (35.3 x 41 x 40) Presented by the artist 1977 Exh: Constructions by N. Gabo, London Gallery, London, January 1938 (3) as «Construction «Torsion» (variant of construction 1929)» 1937; Gabo: Constructions in Space, Wadsworth Atheneum, Hartford, March 1938 (7); Gabo - Pevsner, Museum of Modern Art, New York, February - April 1948 (works not numbered, repr.)

The many comments at Greg's post by a number of contributors considered variants of the Gaussian filter with different criteria for how to minimize side lobes.

The 2 C is a number that has been characterized by all variants of dangerous by leading climate experts, which I interpret to mean that the carbon feedbacks could go on autopilot.

Perhaps the whole country code thing is misbegotten and should be shifted to some more abstract basis — numbered blocks of territory carved up by latitude and longitude, perhaps, or simply some variants of the «type» kind of designation, i.e..

Travel insurance is offered by a number of companies, However, The various overseas travel insurance plans offered by Star health are unique in their nature and each plan comes with a special value added benefit to it, thereby, taking care of all the sudden expenses that can be incurred during travel.Travel insurance by star health comes in a lot of variants.

The patches aimed at mitigating Variant 2 (Spectre) of the three vulnerabilities revealed by Google's Project Zero were causing systems to crash unexpectedly for a number of users.

As a reminder, the Galaxy Note 8 bearing the model number «SM - N950F» is equipped with the Exynos 8895 SoC manufactured by Samsung's chipset division, so given these recent events, there is a possibility that variants powered by the Exynos SoC could receive the update before the models powered by Qualcomm's solution, which were released in North America and China.

This is supposed to be the international variant as indicated by the «F» in the model number and this is the model that appeared in a Geekbench listing.

The firmware is identified by the version number N950FXXU3CRC1 and is available for the international variant of the Galaxy Note 8 bearing the model number «SM - N950F» and the product code «XEF.»

As the model number suggests, this first Galaxy Note 9 benchmark happens to be of the US variant which will be powered by a Qualcomm chip.