Sentences with phrase «numbers of donor cells»

A small number of donor cells in both the intraretinal and subretinal locations were immunopositive for proliferating cell nuclear antigen (PCNA)(Figure 5C and D), even in the oldest rats examined (P150).

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And in a demonstration of just how brazen this particular attack is, TDO actually contacted the cell numbers of various company executives demanding money and threatened to start contacting patients» families and donors, too.
We extract the DNA from the cheek cells and use it to create a series of 32 numbers that are unique to that donor.
Combining an egg's genetic leftovers with donor cells may be a way to double the number of eggs available for IVF in women whose ovarian reserve is running low
Although red cells from donors have a typical shelf life of 42 days, they are a mix of older and newer cells, which means a number of them may not last long in the body.
If researchers could reduce the loss of cells, they could one day treat two or even three times as many patients from the limited number of cadaver donors available, García noted.
«We have just allocated $ 271 million in funds, which leveraged over $ 500 million from donors and the institutions» own reserves to build 12 stem cell institutes in California; these are really large institutes that will accommodate a very large number of scientists,» says Trounson, an Australian native who pioneered in vitro fertilization in the 1980s and relocated to California to head up the CIRM in December 2007.
«This method offers the possibility of inducing large numbers of hair follicles or rejuvenating existing hair follicles, starting with cells grown from just a few hundred donor hairs.
After collecting biopsies from banked human donor eyes, the team expanded the numbers of cells in a culture plate using human serum to nourish them.
This is not easy, however, as it requires a large number of immune cells and a lot of mice need to be bred as donors.
HSC death is a particular problem if the number of donor stem cells is low to begin with.
Using a new method, the scientists therefore isolated T cells specifically programmed to target the CMV virus from the blood of the donor and transferred small numbers of these cells to the patients.
Selective immunoproteasome inhibition using the inhibitor ONX 0914 reduced the number of B cells and plasma cells and suppressed donor - specific allo - antibody production.
Because the egg - donor mother also supplies to each embryo a small number of mitochondria — tiny energy factories within cells that have some of their own genetic material — this approach even affords lesbian couples an approximation of sexual reproduction.
As part of a clinical trial conducted at Northwestern University in Chicago, Illinois, Ildstad and colleagues extracted bone marrow - producing cells from kidney donors and then removed cells likely to cause GVHD while expanding the number of «facilitating cells» that make an organ recipient's system more receptive.
International and regional organizations collect the numbers of transplants annually by disease, donor type, and stem cell source from countries known to perform HSCT in World Health Organization (WHO) member states.
In addition, the parasexual cycle is induced between two a / a mating partners when mixed in ménage a trois matings with a limited number of α / α cells that serve as pheromone donors to trigger unisexual a-a reproduction [43].
Currently, primary hepatocytes are the most common cell model, but their utility is fundamentally constrained by the substantial variation between donors and the finite number of cells that are harvestable from each donor.
Currently, primary hepatocytes are the most common cell model, but their utility is constrained by large variation between donors and a finite number of cells harvestable from each donor.
After an extended number of cell divisions, random segregation of mitochondria may lead to cells containing a majority of mitochondria from the donor egg.
Overall, the number of iPSC mutations — which the researchers suspect were present but undetected in donor blood cells — increased linearly with donor age.
The technical evaluation of projects may require the provision of additional data such as information on the genetic modification of your mutant mouse line if applicable (e.g. affected gene, MGI ID of the gene, type of mutation, ES - cell line used, genetic background (e.g. number of backcross generations), safety level, description of DNA modification, vector, remaining non-recipient DNA, donor organism), mutant phenotype (s), special housing or care requirements, current sanitary status, and intellectual property rights (who generated the mouse line, owner of the mouse line)
To examine the effect of age on the cognate function of CD4 T cells, we have used a novel adoptive transfer model that allows us to compare identical numbers of antigen - specific naive T cells from young and aged TCR transgenic (Tg) donors.
This reduced cognate helper function was seen at all time points and over a wide range of donor cell numbers.
Importantly, the team also found that, in mice, antibody - mediated stimulation of this receptor following a bone marrow transplant increased the number of donor - derived T - cells and boosted initial thymus recovery.
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