The milbemycin - based products will also do the same job but will kill the microfilariae much faster, which can create circulatory shock if there are large
numbers of microfilariae dying all at one time.
The products containing milbemycin (Interceptor and Sentinel) will also kill microfilariae, L3 and L4 larvae but they will do it much faster, which can create circulatory shock if a large
number of microfilariae die at the same time.
The number of microfilariae seen gives us a general indication of the severity of the infection.
Dogs with a very large
number of microfilariae (baby heartworms) can suffer a reaction if those tiny parasites all die at once when given ivermectin.
One 13 - years - old mixed male, with high
number of microfilariae and antigens - positive, died during the therapy.
Not exact matches
Female worms then produce large
numbers of larvae called
microfilariae that move to the skin to be ingested again by biting black flies.
We saw some significant effects, with large drops in
microfilaria numbers, and also an episode
of rather effective «kill»
of heartworm.
Revolution is not effective against adult D. immitis and, while the
number of circulating
microfilariae may decrease following treatment, Revolution is not effective for
microfilariae clearance.
Microfilariae are found in less than 20 %
of feline infections; when they are present they are transient, low in
number and survive only a few weeks.3, 8
The
number of circulating
microfilariae does not correlate with the
number of adult heartworms, so is not an indicator
of disease severity.
Mild, transient hypersensitivity reactions, such as labored breathing, vomiting, hypersalivation, and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high
number of circulating offspring (
microfilariae).
The
number of circulating
microfilaria is greatest during the morning and evening hours coinciding with mosquito activity.
The
number of circulating
microfilaria may vary during different times
of the day.
Diagnosis
of canine dirofilariosis in animals which originate from a low - endemic region is difficult for 3 main reasons: 1) possible absence
of circulating
microfilariae (occult disease), 2) high frequency
of a low
number of adults, which in turn produces false negative results, using either ELISA or latex agglutination test, 3) possible false sero - positive results, due to cross-reaction with adult antigens
of Dirofilaria (Nochtiella) repens (Schrey, 1996), the agent
of subcutaneous dirofilariasis causing chronic pruritic dermatitis in dogs (Tarello, 1999).
As the mosquito stops by for a meal it also sucks up a
number of circulating
microfilariae in the blood.
Microfilariae can be seen in whole blood under the microscope; however, their
numbers are dependent on the
number of mating pairs
of adults in the heart.
Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy have been noted in some treated dogs carrying a high
number of circulating
microfilariae.