Not exact matches
Speaking
of checkpoint inhibitor drugs... Merck's star cancer immunotherapy treatment Keytruda is facing some troubling clinical trial incidents which have now compelled the Food and Drug Administration (FDA) to halt three studies
of the drug in multiple myeloma, a rare
blood cancer, after a
number of patient deaths.
You will get to work with
patients on a regular basis, performing a
number of tasks that range from taking
patients»
blood pressure to putting in IV lines that deliver medication and fluids.
In contrast, PD - L1 blockade increased the capacity
of Treg cells to multiply (and hence their overall
numbers), but only in cells from
patients with viremia, i.e. those that had detectable virus in their
blood.
Researchers at Johns Hopkins Bayview Medical Center used two relatively simple tactics to significantly reduce the
number of unnecessary
blood tests to assess symptoms
of heart attack and chest pain and to achieve a large decrease in
patient charges.
Fat cells cultured from the body mass index
of a morbidly obese
patient cause multiple myeloma cells to anchor to a much greater extent than normal cells and produce a significantly larger
number of blood vessels to sustain the cancer cells.
Patients with diabetes and suffering from acute kidney injury (AKI), proteinuria and uncontrolled
blood sugar experience a sharp reduction in the
number of years they have healthy renal function before being forced onto dialysis, according to researchers at the University
of Cincinnati (UC) College
of Medicine.
Still, WHO experts concluded that this is the best approach because it is theoretically feasible to recruit large
numbers of Ebola survivors, collect
blood from them, screen it for disease and use it to potentially help
patients.
Sîrbulescu notes that it is possible to isolate high
numbers of a
patient's B cells through a standard
blood pheresis procedure, allowing collection
of enough cells for several treatments at a single session.
Dr Lobo continues: «By using the medications we already have available and taking a personalised approach to prescribing these drugs — avoiding an «off the shelf» regime — it allowed
patients to tolerate increased
numbers of medications and ultimately resulted in significant and long lasting lowering
of blood pressure.
A
number of new clinical trials aim to take cells from a
patient, such as
blood cells or immune cells, edit them and transfer them back with new power to undermine diseases like cancer or sickle cell anemia.
Umbilical cord
blood, for example, generally contains insufficient
numbers of stem cells for it to be used as a source
of HSCs for transplantation into adult
patients.
Right under our noses the
patient had lost the
number of red cells contained in almost a quart
of blood — and nobody had the faintest clue why.
Another limitation is that the trial did not select
patients who were at the highest risk for developing another arterial blockage, such as those over age 65, those who have had more than one heart attack or those known to have a large
number of blood clots.
According to Dr. Miedema, «The less stringent
blood pressure goals will increase the
number who are «at goal,» indicating to the
patient and their primary care provider that treatment is not indicated when in fact treatment
of their mildly elevated
blood pressure may reduce their risk for a heart attack and stroke.»
Using a new method, the scientists therefore isolated T cells specifically programmed to target the CMV virus from the
blood of the donor and transferred small
numbers of these cells to the
patients.
The success with kidney transplant
patients is particularly noteworthy given the
number of very ill people who come to the medical center with a high probability
of rejecting a donor organ because
of high amounts
of antibodies in their
blood.
We measured the levels
of Tregs in
patients with ALS, and we found that the disease progressed significantly more slowly in
patients who had higher
numbers of Tregs in their
blood.
«With regard to surgical populations, one
of the questions we had with our NSQIP data, where we track the
number of units
patients receive in the perioperative time period, was whether we would see similar decreases in
blood utilization in the NSQIP population,» said Ms. Martin.
Through the UCSD Clinical Cardiovascular Cell Therapy program, Dib and collaborating cardiology faculty plan to conduct clinical studies in a
number of areas, including the effectiveness
of adult stem cell transplant as a treatment for congestive heart failure; as a way to minimize heart damage after a heart attack; and in the formation
of new
blood vessels (angiogenesis) to increase
blood flow to the heart for
patients experiencing chest pain.
The researchers were able to show that a reduction in the
number of ribosomes — organelles known as the protein factories
of the cell — is responsible for the disruption in the formation
of red
blood cells found in
patients with DBA.
ARANESP ® is used to treat anemia, a deficiency in the
number of red
blood cells, caused by chronic kidney failure in
patients both on dialysis and not on dialysis.
The use
of human embryonic stem cells, as opposed to
patient blood, as the starting material for AST - VAC2 provides a scalable system for the production
of a large
number of vaccine doses in a single lot, reducing manufacturing costs, enabling «off - the - shelf» availability, and ensuring product consistency.
Our physicians and scientists are working on a
number of initiatives, including collecting
blood and bone marrow from
patients to better understand the causes
of bone marrow failure syndromes and MDS; exploring possible genetic factors that guide medical care; collecting
blood and bone marrow to identify specific proteins that are faulty and how these defects relate to clinical complications and outcomes; and clinical trials to improve stem cell transplants for disorders such as dyskeratosis congenita.
«To confirm whether
patients have a bacterial infection
of the respiratory tract, doctors currently have to take a
number of different samples (
blood and septum) and even chest X-rays in the case
of pneumonia,» said project coordinator Kejing Ying in a statement.
In Sabrina's poster, she showed that
patients with a low
number of different types
of T - cells (a type
of immune cell which has different versions to fight different infections / diseases; called a T - cell repertoire or TCR) in their
blood at start
of treatment were more likey to respond to anti-PD1 therapy, and had a poor response to anti-CTLA4 therapy.
However, due to the limited
number of stem cells available, only 10 %
of patients referred for cord
blood transplantation are eligible, which highlights the crucial contribution
of StemCell2MAX for healthcare improvement.
«Glucose
numbers go up quickly with a lot
of my
patients,» he says, referring to
blood - sugar levels.
A decade ago, when researchers at the University
of Indiana put
patients on a low - salt diet, they found that
blood pressure went down in about a third
of patients, but that in an equal
number it actually rose.
According to a study published in Hypertension, 50
patients with resistant hypertension (defined as high
blood pressure that doesn't respond to taking three or more types
of medication designed to lower
blood pressure) who walked on a treadmill at a 3 percent grade three times a week for eight weeks were able to lower their systolic
blood pressure (the
number on the top
of a
blood - pressure reading) by 6 mm Hg (a measure
of pressure).
Long - term dietary treatment with increased amounts
of fiber - rich low - glycemic index natural foods improves
blood glucose control and reduces the
number of hypoglycemic events in type 1 diabetic
patients
A study a
number years ago showed that labeling
patients as hypertensive compared to a control group with the same
blood pressures lowered their quality
of life and increased the days
of work missed.
A 12 - week controlled study in Denmark
of high - intensity interval walking for
patients with Type 2 diabetes showed it helped control
blood glucose levels better than continuous moderate exercise, even though the same
number of calories was expended by both groups.
We recommend running
blood tests on all
patients prior to any anesthetic procedure to check liver and kidney function and also to make sure they have adequate
numbers of red
blood cells, white
blood cells, and platelets.
PRBCs are used to restore the oxygen carrying capacity to the
blood of a
patient that is suffering from anemia (a condition characterized by a decreased
number of red
blood cells or hemoglobin in the
blood), and are one
of the most important
blood components used in transfusion medicine.
• Complete
blood cell count (CBC)- This is a
blood test that looks at the
numbers of white and red
blood cells and platelets as well as the types and abnormalities
of blood cells A CBC may be indicated if the
patient is not in good physical condition because it can detect signs
of infection and anemia which may be significant in the treatment regimen.
Patients with hypertension, or high
blood pressure, may be prescribed a
number of different treatments by their doctors in order to manage their condition.
Lab Technician — ABO Laboratories — May 2012 — Present • Execute a variety
of laboratory assays and tests in accordance with established procedures, policies, and regulations; ensure samples are properly labeled and stored • Study
blood samples for transfusions and record the
blood group,
number of cells,
blood type, cell morphology, and other
blood type compatibility • Perform procedural and instrument calibrations, document all quality control activities, and perform regular equipment maintenance • Identify problems that may negatively affect test results or performance; correct issues immediately and properly notify supervisor • Maintain meticulous records and demonstrate that the testing
of samples is done in the same manner as
patient specimens; promote cost - effective testing practices and reduce waste by 10 percent