Sentences with phrase «numbers of stem cells for»

Umbilical cord blood, for example, generally contains insufficient numbers of stem cells for it to be used as a source of HSCs for transplantation into adult patients.

Not exact matches

He decreed that the case brought by researchers Drs James Sherley and Theresa Deisher, along with a number of Christian groups including the Christian Medical Association, should be heard; and ordered an injunction temporarily blocking federal funding allocated for human - embryonic - stem - cell research.

In addition, where cells derived from embryonic stem cells are great at proliferating — a potentially critical feature if one wants to grow sufficient numbers of cells for clinical use — ones from the iPS lines were much feebler.

Collins and others argue not just for a permanent removal of the injunction to resume research with confidence, but also for an extension of the number of embryonic stem cell lines available to federally funded researchers.

Under the Obama administration, the number of embryonic stem cell lines available for federally funded research had more than tripled, but no money was going toward the creation of any cell lines (a process that destroys the embryo).

When isolated, 99 percent of stem cells die, making it prohibitively difficult to manipulate their genes or expand their numbers for clinical use.

But a number of the invited speakers, including Alan Trounson, president of the California Institute for Regenerative Medicine in San Francisco, and keynote speaker George Daley, a stem - cell scientist at Children's Hospital Boston in Massachusetts, are involved in research using human embryonic stem cells, which the Catholic Church considers unethical.

The country has begun to regain confidence from a series of successful research projects, and is ranked in the world's top ten for stem - cell and regenerative medicine research in terms of number and quality of publications.

«We can work with any embryonic stem cell line from any source and are not restricted to working with the very small number of federally approved lines as is the case for researchers in the United States,» says Minger.

As the skin replenished itself, the holoclones gradually took over, suggesting a small number of stem cells are responsible for growing all the skin.

These human cells were ineligible for federal research funds because they had been created after President Bush's August 9, 2001, announcement freezing the number of government - approved stem cell lines.

Despite this, «one 2009 estimate put the number of stem - cell companies based in China at around 100», says Doug Sipp, a stem - cell ethics and regulation researcher at the RIKEN Center for Developmental Biology in Kobe, Japan.

Small numbers of glioma stem - like cells, or GSCs, drive the tumorigenicity of GBM and thus are prime targets for possible treatments.

«Our group pioneered the development of cell culture technology for harvesting large numbers of stem cells from human bone marrow and human umbilical cord blood,» Dr. Yeh said, noting that stem cells from these two sources are abundant and can be guided into different types of cells using tissue engineering.

Neuroscientists Jing Wang and Freda Miller, both then at Toronto's Hospital for Sick Children, showed that when nondiabetic mice are given metformin, their memory improves, thanks to an increase in the neural stem cell population and in the number of these cells that develop into healthy neurons in the hippocampus, the brain's memory center.

To address these limitations, Zimmer and senior study author Lorenz Studer of the Sloan Kettering Institute for Cancer Research developed a simple, efficient, and robust stem cell - based strategy for reliably producing a large number of diverse, functional pituitary cell types suitable for therapeutic use.

This is both a useful tool for giving us a better understanding of the genetic and epigenetic program controlling the self - renewal of stem cells, and on a practical side, it could allow us to inexpensively produce large numbers of immune cells, which could then be used for regenerative medicine or immune therapy.»

«The use of nonhuman oocytes for SCNT is currently the only ethically justifiable option given the large numbers of eggs required to derive cloned human stem cell lines,» he said.

This allows embryonic stem cells to be employed as useful tools for both research and regenerative medicine, because they can produce limitless numbers of themselves for continued research or clinical use.

Novel stem - cell technology developed at Swinburne will be used to grow the massive number of stem cells required for a new hand - held 3 - D printer that will enable surgeons to create patient - specific bone and cartilage.

Research into Stem Cells has grown exponentially over the past two decades and has already yielded successful or promising therapies for a number of diseases.

While scientists have long known that a group of transcription factors are needed for stem cell maintenance, the sheer number of possible interactions among them has made the question of which are essential too complicated to address in the laboratory alone.

Derivation of pluripotent stem cells, either of embryonic origin or following genetic reprogramming, has opened the path for an alternative source for epidermal cell therapy as these cells are both immortal and pluripotent, theoretically capable of providing any requested number of cells of any desired phenotype.

Through the UCSD Clinical Cardiovascular Cell Therapy program, Dib and collaborating cardiology faculty plan to conduct clinical studies in a number of areas, including the effectiveness of adult stem cell transplant as a treatment for congestive heart failure; as a way to minimize heart damage after a heart attack; and in the formation of new blood vessels (angiogenesis) to increase blood flow to the heart for patients experiencing chest pCell Therapy program, Dib and collaborating cardiology faculty plan to conduct clinical studies in a number of areas, including the effectiveness of adult stem cell transplant as a treatment for congestive heart failure; as a way to minimize heart damage after a heart attack; and in the formation of new blood vessels (angiogenesis) to increase blood flow to the heart for patients experiencing chest pcell transplant as a treatment for congestive heart failure; as a way to minimize heart damage after a heart attack; and in the formation of new blood vessels (angiogenesis) to increase blood flow to the heart for patients experiencing chest pain.

Mouse embryonic stem cells stained for key pluripotency markersGRAZIANO MARTELLO Combining computer science algorithms with biological data has enabled researchers to create a model of the minimal number of factors necessary for mouse embryonic stem cells (ESCs) to self - renew in culture.

In the past few years a number of techniques for the derivation of pluripotent cells without the destruction of embryos have begun to emerge, and one in particular has made great strides: the development of so - called induced pluripotent stem (iPS) cells.

Our goals are to understand and overcome the limitations of regeneration in the mammalian retina, so that endogenous retinal cells are reprogrammed into an adult stem cell and generate adequate progenitor progeny to provide sufficient cell numbers and types for neuronal regeneration.

Often the feasibility of using stem cells for regenerative therapies is limited by two factors: obtaining a significant number of cells and doing so in a relatively noninvasive manner.

Not so long ago, human embryonic stem cell (hESC) research and SCNT were being hailed as the future of regenerative medicine, capable of generating cures and therapies for any number of diseases and conditions.

Embryonic stem cells (ESCs) represent a source for the large numbers of modified EPCs required to therapeutically inhibit tumorigenesis [3], although patient - specific induced pluripotent stem cells (iPSCs) represent a more attractive option.

Chris is on a number of national and international committees, working groups and initiatives related to the academic, clinical translation and commercialization of cell and gene therapies including; Founder and CEO of the London Regenerative Medicine Network (LRMN), Founding Member of the UK - Israel Science Council, Scientific Advisory Board of the UK Cell and Gene Therapy Catapult, Strategic Advisory Board of the Canadian Centre for the Commercialization of Regenerative Medicine (CCRM), and Scientific Advisory Board of the Canadian Stem Cell Netwcell and gene therapies including; Founder and CEO of the London Regenerative Medicine Network (LRMN), Founding Member of the UK - Israel Science Council, Scientific Advisory Board of the UK Cell and Gene Therapy Catapult, Strategic Advisory Board of the Canadian Centre for the Commercialization of Regenerative Medicine (CCRM), and Scientific Advisory Board of the Canadian Stem Cell NetwCell and Gene Therapy Catapult, Strategic Advisory Board of the Canadian Centre for the Commercialization of Regenerative Medicine (CCRM), and Scientific Advisory Board of the Canadian Stem Cell NetwCell Network.

Because the intestine relies on the function of resident intestinal stem cells (ISCs) for survival, its homeostasis is intimately linked to stem cell number.

The question arises nearly every day and it is not surprising given the abundance of articles and advertisements promoting the use of «stem cell treatments» for a staggering number of diseases and injuries.

Based on positive results produced from a number of scientific clinical trials, coronary artery disease therapy using adult stem cells is a promising new method of treatment for coronary artery disease patients.

But, by focusing on tissue obtained from mouse embryos, the Salk researchers were able for the first time to identify and isolate a sufficiently large number of fetal breast stem cells to begin to understand how their GPS works.

The largest number of adult stem cells is present in the umbilical cord blood and in bone marrow and they have been used effectively for decades to treat cancers, blood and immune disorders.

While human cord blood represents a potentially important source of hematopoietic stem and progenitor cells (HSPC), current two dimensional (2D) growth conditions employed to amplify cell numbers to the level required for many regenerative applications lead to a decline in the absolute percentage of the most primitive HSPCs [1].

«As the only engineer in the U.S. Senate,» Sununu said, «I've been proud to protect funding for the National Science Foundation from political manipulation and fully support funding for adult and amniotic stem cell research — which has already resulted in a number of treatments that have proven to be successful in patient trials.»

A limited number of activities will also be directed toward the public to promote the level of understanding for informed decisions and to present the possibilities and problems that surround stem cell therapies for neurodegenerative diseases.

The use of human embryonic stem cells, as opposed to patient blood, as the starting material for AST - VAC2 provides a scalable system for the production of a large number of vaccine doses in a single lot, reducing manufacturing costs, enabling «off - the - shelf» availability, and ensuring product consistency.

Due to the large number of hES cells and human induced Pluripotent Stem (hiPS) cells needed by I - Stem's research groups, the development of large - scale culture systems for expansion and differentiation of those cells is critical.

Our physicians and scientists are working on a number of initiatives, including collecting blood and bone marrow from patients to better understand the causes of bone marrow failure syndromes and MDS; exploring possible genetic factors that guide medical care; collecting blood and bone marrow to identify specific proteins that are faulty and how these defects relate to clinical complications and outcomes; and clinical trials to improve stem cell transplants for disorders such as dyskeratosis congenita.

Many scientists argue that stem cells are our best hope for curing a huge number of diseases.

In April 2004, more than 200 members of the U.S. House of Representatives sent President Bush a letter, asking him to increase the number of human embryonic stem cell lines that should be eligible for public funding.

An increasing number of foreigners are undergoing stem cell treatment in Costa Rica for ailments from bone fractures to multiple sclerosis.

In April of 2004, a letter bearing 206 signatures of Members of the United States House of Representatives was sent to President George Bush, asking him to increase the number of human embryonic stem cell lines that should be eligible for public funding.

They suggest that further research should be performed over a longer time period and in a greater number of animals to determine whether these improvements are maintained, and look forward to further work utilizing membrane - spanning peptides for presentation of bioactive molecules for stem cell therapy.

Excitingly, because stem cells can produce such large numbers of neurons, we can even test for and identify new drug candidates using patient specific neurons.

Notch signaling is essential for radial glia stem cell proliferation and a determinant of neuronal number in the mammalian cortex.

The existence of cancer stem cells has been amply demonstrated for a number of cancer types, including breast cancer (20, 21).