Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect
of lowering prices or reducing the
number of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and
current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical
studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
A newly released
study by Pew Research Center found that 91 percent
of the
current U.S. Congress identify as Christian — a
number that has not changed much in more than 50 years, despite its constituency's Christian identity declining.
As representatives
of the minimalists I will consider Edward Schillebeeckx's Jesus: An Experiment in Christology (Crossroad Publishing Co., 1979), a long and weighty
study of current New Testament scholarship, and Thomas Sheehan's The First Coming: How the Kingdom
of God Became Christianity (Random House, 1986), a more accessible argument based on the results
of Schillebeeckx and a
number of others.
This allows any
current student on a recognised course
of study within the University, irrespective
of matriculation or
number of years
of previous participation, the right to play.
According to the most
current study, the
number of women who choose to breastfeed in the United States continues to rise, with 77 percent
of new moms reporting they at least breastfed their babies for the first few months
of their life, if not for a year — or years.
That year, women delivering at birth centers had C - sections 4 %
of the time; that
number grew to just 6 % in the
current study, which relied on figures from 2007 to 2010 from 79 midwife - led birth centers in 33 states.
This is in line with many other
studies: a 2005 poll found that 29 per cent were content with the
current number of abortions that take place each year.
«After already being able to demonstrate the influence
of prenatal smoking on regulatory T - cell
numbers in cord blood from our LINA
study, the
current epidemiological investigation delves even deeper into molecular processes,» Dr. Gunda Herberth and Dr. Irina Lehmann resume.
Additionally, the
study authors noted, the
number of people who had access to safe — and not just improved — water in 1990 was likely much lower than previously estimated, which means that the 2015 target is even farther away than estimated by the
current rubric.
Using DNA profiling, Garry Russ and colleagues at the ARC Centre
of Excellence for Coral Reef
Studies in Queensland, Australia, have shown that devoting less than a third
of an area to a marine reserve network doubled the
number of juvenile fish in the rest
of the area (
Current Biology, DOI: 10.1016 / j.cub.2012.04.008).
Not long after the HD gene was isolated,
studies led by MacDonald, also a co-author
of the
current investigation, found that a variation in the
number of CAG trinucleotide repeats within the HD gene, which codes for a protein called huntingtin, is the primary determinant
of the age at which HD symptoms appear, with a greater
number of CAG repeats associated with an earlier symptom onset.
Published revision rates for septorhinoplasty procedures in the
current facial plastic surgery literature are limited to a small
number of studies focused on a single institution or a single surgeon.
In his own words: «Our
current study stresses the importance
of non-spatial
number representations.
«As these drugs are considerably cheaper than
current therapies, they can improve treatment in the developing world where the
number of deaths from cancer is predicted to increase significantly over the next ten years,» said Dr Federica Sotgia, another leader
of the
study.
While the
current study controlled for a large
number of vascular risk factors, no information was available for vascular biomarkers, and migraine specifics, such as migraine aura.
The results
of the
study by Marc Baguelin and colleagues from the London School
of Hygiene & Tropical Medicine in the UK, Public Health England, and Athens University
of Economics and Business, show that the
current flu vaccination policy that targets people aged 65 years and over and also those in high risk groups has reduced the
number of flu infections and associated deaths in these groups over the past 14 years.
The
current influenza (flu) vaccination policy in England and Wales should be expanded to target 5 to 16 - year - olds in order to further reduce the
number of deaths from flu, according to a
study by UK researchers published in this week's PLOS Medicine.
Anthropologist Nina Jablonski, profiled by Ann Gibbons (p. 934),
studies the evolution
of skin color and has found that a surprising
number of people face health consequences from having a skin tone poorly adapted to their
current environment.
Noting that the timing
of KD outbreaks in Japan coincides with certain wind patterns from Asia, climate scientist Xavier Rodó, PhD, and colleagues at the Catalan Institution for Research and Advanced
Studies and the Catalan Institute
of Climate Sciences, both in Barcelona, used computer models to simulate air
currents and airborne particle transport for all days since 1977 with high
numbers of KD cases in Japan, based on data compiled by Yoshikazu Nakamura, MD, and colleagues at Jichi Medical University in Japan.
Since high coverage and compliance rates can be difficult to achieve with the
current three - dose HPV vaccineregimen, several
studies have looked at the possibility
of reducing the
number of doses.
Because most clinicians are likely to see smokers at times when a quit date in the next month is not planned, the
current study indicates that prescription
of varenicline with a recommendation to reduce the
number of cigarettes smoked per day with the eventual goal
of quitting could be a useful therapeutic option for this population
of smokers.
«The
numbers should be a wake - up call that we urgently need to apply freshwater conservation efforts,» says Marguerite A. Xenopoulos
of Trent University in Ontario, who authored a 2005
study on freshwater fish extinctions but was not involved in the
current research.
One limitation to the
current study is that it analyzed less than 2 %
of the total
number of papers published from 2007 to 2013.
And, because
of the
current faculty age structure, the
number of retiring professors should «increase dramatically» over the next 5 to 10 years if
current retirement patterns hold, states Mark Regets, senior analyst at the National Science Foundation's Division
of Science Resource
Studies.
In the
current study, a
number of prognostic factors such as age, stage, comorbidity, hormonal receptor and HER2 status and differences in systemic treatments (medication after surgery) were included and considered as possible explanations for the previously reported survival differences between BCT and mastectomy.
g (acceleration due to gravity) G (gravitational constant) G star G1.9 +0.3 gabbro Gabor, Dennis (1900 — 1979) Gabriel's Horn Gacrux (Gamma Crucis) gadolinium Gagarin, Yuri Alexeyevich (1934 — 1968) Gagarin Cosmonaut Training Center GAIA Gaia Hypothesis galactic anticenter galactic bulge galactic center Galactic Club galactic coordinates galactic disk galactic empire galactic equator galactic habitable zone galactic halo galactic magnetic field galactic noise galactic plane galactic rotation galactose Galatea GALAXIES galaxy galaxy cannibalism galaxy classification galaxy formation galaxy interaction galaxy merger Galaxy, The Galaxy satellite series Gale Crater Galen (c. AD 129 — c. 216) galena GALEX (Galaxy Evolution Explorer) Galilean satellites Galilean telescope Galileo (Galilei, Galileo)(1564 — 1642) Galileo (spacecraft) Galileo Europa Mission (GEM) Galileo satellite navigation system gall gall bladder Galle, Johann Gottfried (1812 — 1910) gallic acid gallium gallon gallstone Galois, Évariste (1811 — 1832) Galois theory Galton, Francis (1822 — 1911) Galvani, Luigi (1737 — 1798) galvanizing galvanometer game game theory GAMES AND PUZZLES gamete gametophyte Gamma (Soviet orbiting telescope) Gamma Cassiopeiae Gamma Cassiopeiae star gamma function gamma globulin gamma rays Gamma Velorum gamma - ray burst gamma - ray satellites Gamow, George (1904 — 1968) ganglion gangrene Ganswindt, Hermann (1856 — 1934) Ganymede «garbage theory»,
of the origin
of life Gardner, Martin (1914 — 2010) Garneau, Marc (1949 ---RRB- garnet Garnet Star (Mu Cephei) Garnet Star Nebula (IC 1396) garnierite Garriott, Owen K. (1930 ---RRB- Garuda gas gas chromatography gas constant gas giant gas laws gas - bounded nebula gaseous nebula gaseous propellant gaseous - propellant rocket engine gasoline Gaspra (minor planet 951) Gassendi, Pierre (1592 — 1655) gastric juice gastrin gastrocnemius gastroenteritis gastrointestinal tract gastropod gastrulation Gatewood, George D. (1940 ---RRB- Gauer - Henry reflex gauge boson gauge theory gauss (unit) Gauss, Carl Friedrich (1777 — 1855) Gaussian distribution Gay - Lussac, Joseph Louis (1778 — 1850) GCOM (Global Change Observing Mission) Geber (c. 720 — 815) gegenschein Geiger, Hans Wilhelm (1882 — 1945) Geiger - Müller counter Giessler tube gel gelatin Gelfond's theorem Gell - Mann, Murray (1929 ---RRB- GEM «gemination,»
of martian canals Geminga Gemini (constellation) Gemini Observatory Gemini Project Gemini - Titan II gemstone gene gene expression gene mapping gene pool gene therapy gene transfer General Catalogue
of Variable Stars (GCVS) general precession general theory
of relativity generation ship generator Genesis (inflatable orbiting module) Genesis (sample return probe) genetic code genetic counseling genetic disorder genetic drift genetic engineering genetic marker genetic material genetic pool genetic recombination genetics GENETICS AND HEREDITY Geneva Extrasolar Planet Search Program genome genome, interstellar transmission
of genotype gentian violet genus geoboard geode geodesic geodesy geodesy satellites geodetic precession Geographos (minor planet 1620) geography GEOGRAPHY Geo - IK geologic time geology GEOLOGY AND PLANETARY SCIENCE geomagnetic field geomagnetic storm geometric mean geometric sequence geometry GEOMETRY geometry puzzles geophysics GEOS (Geodetic Earth Orbiting Satellite) Geosat geostationary orbit geosynchronous orbit geosynchronous / geostationary transfer orbit (GTO) geosyncline Geotail (satellite) geotropism germ germ cells Germain, Sophie (1776 — 1831) German Rocket Society germanium germination Gesner, Konrad von (1516 — 1565) gestation Get Off the Earth puzzle Gettier problem geyser g - force GFO (Geosat Follow - On) GFZ - 1 (GeoForschungsZentrum) ghost crater Ghost Head Nebula (NGC 2080) ghost image Ghost
of Jupiter (NGC 3242) Giacconi, Riccardo (1931 ---RRB- Giacobini - Zinner, Comet (Comet 21P /) Giaever, Ivar (1929 ---RRB- giant branch Giant Magellan Telescope giant molecular cloud giant planet giant star Giant's Causeway Giauque, William Francis (1895 — 1982) gibberellins Gibbs, Josiah Willard (1839 — 1903) Gibbs free energy Gibson, Edward G. (1936 ---RRB- Gilbert, William (1544 — 1603) gilbert (unit) Gilbreath's conjecture gilding gill gill (unit) Gilruth, Robert R. (1913 — 2000) gilsonite gimbal Ginga ginkgo Giotto (ESA Halley probe) GIRD (Gruppa Isutcheniya Reaktivnovo Dvisheniya) girder glacial drift glacial groove glacier gland Glaser, Donald Arthur (1926 — 2013) Glashow, Sheldon (1932 ---RRB- glass GLAST (Gamma - ray Large Area Space Telescope) Glauber, Johann Rudolf (1607 — 1670) glaucoma glauconite Glenn, John Herschel, Jr. (1921 ---RRB- Glenn Research Center Glennan, T (homas) Keith (1905 — 1995) glenoid cavity glia glial cell glider Gliese 229B Gliese 581 Gliese 67 (HD 10307, HIP 7918) Gliese 710 (HD 168442, HIP 89825) Gliese 86 Gliese 876 Gliese Catalogue glioma glissette glitch Global Astrometric Interferometer for Astrophysics (GAIA) Global Oscillation Network Group (GONG) Globalstar globe Globigerina globular cluster globular proteins globule globulin globus pallidus GLOMR (Global Low Orbiting Message Relay) GLONASS (Global Navigation Satellite System) glossopharyngeal nerve Gloster E. 28/39 glottis glow - worm glucagon glucocorticoid glucose glucoside gluon Glushko, Valentin Petrovitch (1908 — 1989) glutamic acid glutamine gluten gluteus maximus glycerol glycine glycogen glycol glycolysis glycoprotein glycosidic bond glycosuria glyoxysome GMS (Geosynchronous Meteorological Satellite) GMT (Greenwich Mean Time) Gnathostomata gneiss Go Go, No - go goblet cell GOCE (Gravity field and steady - state Ocean Circulation Explorer) God Goddard, Robert Hutchings (1882 — 1945) Goddard Institute for Space
Studies Goddard Space Flight Center Gödel, Kurt (1906 — 1978) Gödel universe Godwin, Francis (1562 — 1633) GOES (Geostationary Operational Environmental Satellite) goethite goiter gold Gold, Thomas (1920 — 2004) Goldbach conjecture golden ratio (phi) Goldin, Daniel Saul (1940 ---RRB- gold - leaf electroscope Goldstone Tracking Facility Golgi, Camillo (1844 — 1926) Golgi apparatus Golomb, Solomon W. (1932 — 2016) golygon GOMS (Geostationary Operational Meteorological Satellite) gonad gonadotrophin - releasing hormone gonadotrophins Gondwanaland Gonets goniatite goniometer gonorrhea Goodricke, John (1764 — 1786) googol Gordian Knot Gordon, Richard Francis, Jr. (1929 — 2017) Gore, John Ellard (1845 — 1910) gorge gorilla Gorizont Gott loop Goudsmit, Samuel Abraham (1902 — 1978) Gould, Benjamin Apthorp (1824 — 1896) Gould, Stephen Jay (1941 — 2002) Gould Belt gout governor GPS (Global Positioning System) Graaf, Regnier de (1641 — 1673) Graafian follicle GRAB graben GRACE (Gravity Recovery and Climate Experiment) graceful graph gradient Graham, Ronald (1935 ---RRB- Graham, Thomas (1805 — 1869) Graham's law
of diffusion Graham's
number GRAIL (Gravity Recovery and Interior Laboratory) grain (cereal) grain (unit) gram gram - atom Gramme, Zénobe Théophile (1826 — 1901) gramophone Gram's stain Gran Telescopio Canarias (GTC) Granat Grand Tour grand unified theory (GUT) Grandfather Paradox Granit, Ragnar Arthur (1900 — 1991) granite granulation granule granulocyte graph graph theory graphene graphite GRAPHS AND GRAPH THEORY graptolite grass grassland gravel graveyard orbit gravimeter gravimetric analysis Gravitational Biology Facility gravitational collapse gravitational constant (G) gravitational instability gravitational lens gravitational life gravitational lock gravitational microlensing GRAVITATIONAL PHYSICS gravitational slingshot effect gravitational waves graviton gravity gravity gradient gravity gradient stabilization Gravity Probe A Gravity Probe B gravity - assist gray (Gy) gray goo gray matter grazing - incidence telescope Great Annihilator Great Attractor great circle Great Comets Great Hercules Cluster (M13, NGC 6205) Great Monad Great Observatories Great Red Spot Great Rift (in Milky Way) Great Rift Valley Great Square
of Pegasus Great Wall greater omentum greatest elongation Green, George (1793 — 1841) Green, Nathaniel E. Green, Thomas Hill (1836 — 1882) green algae Green Bank Green Bank conference (1961) Green Bank Telescope green flash greenhouse effect greenhouse gases Green's theorem Greg, Percy (1836 — 1889) Gregorian calendar Grelling's paradox Griffith, George (1857 — 1906) Griffith Observatory Grignard, François Auguste Victor (1871 — 1935) Grignard reagent grike Grimaldi, Francesco Maria (1618 — 1663) Grissom, Virgil (1926 — 1967) grit gritstone Groom Lake Groombridge 34 Groombridge Catalogue gross ground, electrical ground state ground - track group group theory GROUPS AND GROUP THEORY growing season growth growth hormone growth hormone - releasing hormone growth plate Grudge, Project Gruithuisen, Franz von Paula (1774 — 1852) Grus (constellation) Grus Quartet (NGC 7552, NGC 7582, NGC 7590, and NGC 7599) GSLV (Geosynchronous Satellite Launch Vehicle) g - suit G - type asteroid Guericke, Otto von (1602 — 1686) guanine Guiana Space Centre guidance, inertial Guide Star Catalog (GSC) guided missile guided missiles, postwar development Guillaume, Charles Édouard (1861 — 1938) Gulf Stream (ocean
current) Gulfstream (jet plane) Gullstrand, Allvar (1862 — 1930) gum Gum Nebula gun metal gunpowder Gurwin Gusev Crater gut Gutenberg, Johann (c. 1400 — 1468) Guy, Richard Kenneth (1916 ---RRB- guyot Guzman Prize gymnosperm gynecology gynoecium gypsum gyrocompass gyrofrequency gyropilot gyroscope gyrostabilizer Gyulbudagian's Nebula (HH215)
While there are trends in certain vaginal microbiota and increased risk in acquiring transient and persistent HPV infections,
current studies are heterogenous in nature and describe relatively small
numbers of cohorts with limited control groups.
Analyzing this woman's virus for their
current study, the researchers found that it contained mutations in four amino acids in the envelope protein, two
of which, when introduced into unrelated strains
of HIV in the laboratory, rendered each virus sensitive to a
number of antibodies produced in people infected with HIV, including those directed to more conserved regions.
Results: The
number of days
of extreme fire risk in California might be six times the
current number by the end
of the century, according to a
study led by scientists at Pacific Northwest National Laboratory.
The
current study evaluates how CAG repeat
number affects both the age
of onset and the progression
of disease in the R6 / 2 mouse model
of Huntington's disease (Mangiarini et al., 1996) by concurrently evaluating R6 / 2 mice with either 110 or 240 CAG repeats in an F1 hybrid background (C57Bl / 6 x CBA / CaJ).
From his own research in chemical oceanography, along with data from a
number of recent
studies, Weber points out that some negative consequences
of greenhouse gas emissions and warming «are manifesting faster than previously predicted,» including ocean acidification and oxygen loss, which are expected to affect «a large fraction
of marine species if
current trends continue unchecked.»
[19] In the
current study, [15] PDGF - AS mice exhibited an increased
number and intensity
of areas staining for reactive microglia (using Iba1) and astroglia (using GFAP), but vaccination with AFF 1 prevented nearly all
of this disease - associated excess, with treated animals exhibiting only the burden
of reactive glia present in similar - aged WT mice.
Bill has conducted a
number of «plankton to predator»
studies in the California
Current large marine ecosystem, and has written about climate effects on seabirds, marine mammals and fish.
We
study a
number of different types
of cancer, but our
current focus is on prostate cancer.
The results
of our
study on the conservation
of the
number of digits provides an important argument in the
current controversy on the descent
of birds from dinosaurs between developmental biologists and paleontologists.
Limitations
of the
current study are the relatively low
number of participants as well as the fact that their fitness were tested at only one occasion.
Lund University offers a
number of services and tools to help you as a
current student with matters related to your
studies.
«With this (technology), the center will provide the biology research community with tools to
study an enormous
number of biological systems that are currently inaccessible by
current X-ray methods,» says NSF Chemistry
of Life Processes Program Manager David Rockcliffe.
Although coffee consumption was inversely associated with diabetes, it was also positively associated with a
number of behaviors that are considered unhealthy and are associated with an increased risk
of death, such as tobacco smoking, 35 consumption
of red meat, 36 and heavy alcohol use.37 Tobacco smoking was the strongest confounder in the multivariate analysis, and the inverse association between coffee consumption and mortality tended to be stronger among persons who had never smoked or were former smokers than among those who were
current smokers, suggesting that residual confounding by smoking status, if present, attenuated the inverse associations between coffee drinking and mortality in our
study.
The
study's researchers advised that considering the
current epidemic levels
of insulin resistance as seen in the massive
numbers of type 2 diabetes cases and obesity, reducing intake
of refined carbs and sugar along with weight control should be a top priority in the public's dietary goals.
This most recent
study discovered that many psoriasis and psoriatic arthritis patients living in America in particular, are unhappy with their
current treatments, and dissatisfaction with the results and unwanted side effects being the two biggest reasons why a large
number of psoriasis and psoriatic arthritis patients go untreated or abandon conventional treatment, according to this 2013
study that spanned research based on patients interviewed between 2003 and 2011.
To specifically address these questions, recent review articles published in influential, peer - reviewed publications were selected for this
current discussion, as these review articles rigorously evaluate and summarize findings across a
number of scientific
studies and provide the overall «state
of knowledge.»
There are a
number of reasons: 1) student achievement probably wasn't used as the measure
of teacher effectiveness; 2) before the advent
of the modern computer, in the mid-1960s, some
of the more sophisticated analyses were not feasible; 3) the structure and makeup
of schools change, making the findings less applicable to the
current situation; 4) most important, older
studies may not control for critical variables, such as students» backgrounds or past achievement.
Ironically, on the plus side, the
current funding and recruitment crisis means that the
number of language teachers needed for 90 %
of students to
study the EBACC will take ages to materialise unless something really radical happens — like joined up thinking for once.
The
study also found schools that serve many
current and former English learner students tended to offer fewer advanced courses compared with schools that serve only a small
number of English learner students — even when holding constant characteristics such as size and students» performance on state assessments.
After the introduction
of the English Baccalaureate (EBacc), which requires every
current year 7 to
study English, maths, science, history or geography and a modern foreign language until they are 16, there was an initial increase in the proportion
of pupils taking a language at GCSE, but this
number has now stagnated.
Magnet Schools
of America commissioned a
study with the University
of North Carolina — Charlotte's Urban Institute to compile a comprehensive and more
current count
of the
number of magnet schools across the country, as many school districts have broadened what it means to be a magnet school.
Not according to a
number of financial experts, including Robert Abboud, an Ottawa — based CFP and the author
of No Regrets: A common sense guide to achieving and affording your life goals, our very own Canadian Capitalist blogger, Ram Balakrishnan, and Dr. Moshe Milevsky, the York university professor whose initial 2001
study became the impetus behind the
current belief that you'll always save with a variable rate mortgage.
Current studies are investigating breed predispositions to a
number of other diseases, including equine metabolic syndrome and laminitis.
Nights Aren't Cooling As Much As They Used To Interestingly, the
study also found that part
of the reason for the 2:1 ratio can be attributed to comparatively smaller
numbers of record lows than huge
numbers of record highs — indicating that much
of current warming is occurring at night, something which is «consistent with years
of climate model research.»