Sentences with phrase «numerous cell mutations»

Rather than artificially triggering cancer by engineering genetic mutations, this model more closely mimics human liver cancer in that tumors develop as a natural consequence of non-alcoholic steatohepatitis (NASH), a chronic metabolic disorder that causes liver damage, fibrosis and numerous cell mutations.

Not exact matches

To answer this question, the researchers created numerous premature stop signs, known as nonsense mutations, in test genes in human and yeast cells.

But cells with a pro-growth mutation can outcompete other cells, become very numerous, and «take over» a tissue.

«We wanted to understand why numerous mutations accumulate in cells with activated oncogenes,» explains Thanos Halazonetis, Professor at the Department of Molecular Biology of the UNIGE Faculty of Science.

Each cancer is founded by a single somatic cell that has genetically diverged from its relatives through new mutations, and most tumor cells harbor numerous genetic alterations.