Sentences with phrase «numerous genes in the cells»

The scientists noticed several abnormalities in the heart cells created from the patients: the cells beat weaker than normal, and numerous genes in the cells were abnormally activated or silenced.

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To answer this question, the researchers created numerous premature stop signs, known as nonsense mutations, in test genes in human and yeast cells.

They found numerous genes activated in the XYL regulon - controlled yeast that upregulated pathways involved in growth, such as cell wall maintenance, cell division, mitochondrial biogenesis and adenosine triphosphate (ATP) production.

Indeed, after Siddle added a squirt of interferon - gamma — a chemical messenger that activates numerous genes involved in producing MHC antigens — to cells cultured from devil tumors, the MHC genes functioned normally again, and the tumor cells» identity cards showed up, plain as day.

The researchers ran numerous experiments in cell cultures and mice to observe what happened to Salmonella in the inflamed gut when these genes were mutated.

The advent of genomics and rapid sequencing techniques has seen HeLa cells used in numerous large - scale studies of gene function and expression.

«By looking comprehensively at gene expression within cells, we can now spot numerous important differences in complex tissues like the brain that are invisible today,» said George Church, Ph.D., a Core Faculty member at the Wyss Institute and Professor of Genetics at Harvard Medical School.

In cancer, a state marked by increased protein translation and biomass expansion, HSF1 is activated and binds to numerous genes throughout the genome, as seen in the heat map of HSF1 ChIP - Seq read density in M0 - 91acute myeloid leukemia cells (DMSO, far leftIn cancer, a state marked by increased protein translation and biomass expansion, HSF1 is activated and binds to numerous genes throughout the genome, as seen in the heat map of HSF1 ChIP - Seq read density in M0 - 91acute myeloid leukemia cells (DMSO, far leftin the heat map of HSF1 ChIP - Seq read density in M0 - 91acute myeloid leukemia cells (DMSO, far leftin M0 - 91acute myeloid leukemia cells (DMSO, far left).

A motif found in numerous genes that are essential for the proper function of macrophages and B cells.

In the past few years, FANTOM researchers have applied Cap Analysis Gene Expression (CAGE), a genomic technology developed at RIKEN, to numerous mammalian cell and tissue types.

For example, by using histone deacetylase (HDAC) inhibitors, which, by remodeling chromatin structure, are thought to promote gene expression broadly, including for SMN2, numerous groups showed that they could increase SMN protein levels — both truncated and full - length — in mouse models of SMA as well as in patient - derived cell lines.

AAEM pointed to numerous animal studies that showed oxidative stress, altered structure and function of the liver, intestinal damage, disruption of the immune system, increased cell growth and hundreds of alterations in gene expressions.