Sentences with phrase «nutrient deprivation»

We can't live in a constant state of nutrient deprivation.

In response to a variety of stress signals, including nutrient deprivation, oxidative stress, dysfunctional telomeres, DNA damage and oncogene overexpression, normally dividing cells can permanently withdraw from the typical cell cycle.

However, a growing number of recent studies have demonstrated that fasting may be a more advisable choice for nutrient deprivation in these patients, for which the reasons are listed as the followings.

Anorexia and alterations in food perception, including taste and smell, are often present in dogs with cancer and further contribute to nutrient deprivation in normal dog cells, and hence to the overall body condition loss in the pet.

But as halofuginone mimics nutrient deprivation, there is another possible use.

«Nutrient deprivation kills kidney cancer cells: Cutting off amino acid triggers cell death in cancers.»

The authors caution that these results contrast with, but are not necessarily incompatible with, the idea that adverse events taking place in the womb (such as nutrient deprivation) trigger diseases later in life.

Nutrient deprivation represents a logical strategy to kill cancer cells; yet none of the currently available anti-cancer drug development programmes has seized the opportunity to utilize this strategy.

Nutrient deprivation encompasses several forms of dietary restriction including CR and fasting.

Autophagy, a cellular cleaning process, gets activated in response to certain types of metabolic stress, including nutrient deprivation, growth factor depletion and hypoxia.

«We suspect this communication system between adipose tissue and liver may have evolved to help fat cells command the liver to supply the body with glucose in times of nutrient deprivation.

It functions in the clearance of misfolded proteins and damaged organelles, as well as recycling of cytosolic components during starvation to compensate for nutrient deprivation.

Tang subjected the cancer cells to a nutrient deprivation test, removing each of the 15 amino acids from their growth media, one by one.

«We found that the same machinery that makes these tumors so aggressive also makes them vulnerable to nutrient deprivation,» said senior study author Jen - Tsan Ashley Chi, Ph.D., associate professor of molecular biology and microbiology at Duke University School of Medicine.

To study the effect of hypoxia / reoxygenation cycles on breast cancer, we exposed two metastatic human breast cancer cell lines (MDA - MB 231 and BCM2) to cycles of chronic hypoxia and nutrient deprivation.

The ability to conveniently characterise the glycolytic profile of in vitro cell models used in these disease areas and to determine how specific stress interventions (eg, nutrient deprivation, hypoxia, drug treatment) impact that profile is therefore of considerable interest.

The GCN2 - ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation

Important distinction: Fasting is not the same as either calorie restriction (a 20 - 40 % reduction in calorie intake) or starvation (a prolonged state of nutrient deprivation).

Not because of a fast (nutrient deprivation) inherently being beneficial.

It can occur without caloric restriction, without the risk of nutrient deprivation, and can have other systemwide benefits too, such as improvements in gait, reduced markers of aging, and cognitive function.