Sentences with phrase «obese diabetic mice»

But in September, Umut Ozcan, an obesity researcher at Children's Hospital Boston, reported that a key inflammatory protein actually reduces insulin resistance in obese diabetic mice, curing them of diabetes.

Ozcan realized that inflammation might help when he noticed that in obese diabetic mice, XBP - 1s failed to enter the cell nucleus, where insulin function is regulated.

The U-M study explains how increased cAMP in fat cells promotes the secretion of the hormone interleukin - 6, which signals the liver to stop producing glucose — thus improving overall blood sugar levels in obese diabetic mice.

Remarkably, the same healing effect was produced when B cells from older obese diabetic mice were applied to acute wounds in similarly aged, obese diabetic mice.

Probing the link between adiponectin deficiency and metabolic disorders like diabetes and obesity, researchers from the Albert Einstein College of Medicine in New York City injected adiponectin into wild - type mice, diabetic mice, and obese diabetic mice.

Not exact matches

The drug, SRT1720, kept mice with high - calorie diets from becoming obese or diabetic, according to a study published in Cell Metabolism [subscription required].

Next, they reduced the blood aP2 levels in obese and diabetic mice to low levels seen in lean healthy mice.

«But what was really surprising was that when obese mutant mice were given metformin, the most common and inexpensive drug prescribed to Type 2 diabetics, the drug failed to lower their blood sugar levels,» said Steinberg.

The genetically obese and diabetic mice showed similar metabolic benefits from both WBV and exercising on the treadmill.

In fact, metabolic benefits were almost the same for genetically obese and diabetic mice from both WBV and those exercising on the treadmill.

In our previous study we found that a high fat diet containing comparable amounts of soybean oil to what Americans are currently consuming caused mice to become obese, diabetic and insulin resistant and to have large lipid droplets and hepatocyte ballooning in their livers.

Just 12 weeks of the high fat diet made mice obese and diabetic, nearly doubling their body fat percentage compared to mice fed a low fat, healthy diet.

Oligofructose even made the obese mice less diabetic, but there was one thing the dietary supplement didn't change: body weight.

In diabetic non ‐ obese diabetic (NOD) mice, adipose - derived MSCs (ASCs) have been shown to decrease hyperglycemia and insulitis through attenuation of the Th1 immune response and expansion of T regulatory lymphocytes [3].

Male C57BL / 6J obese mice fed a high - fat diet for 12 weeks and genetically diabetic db / db mice at an age of 6 weeks received dietary C3G supplementation (0.2 %) for 5 weeks.

This study has examined the effect of alpha - lipoic acid on glucose uptake by cultured L6 muscle cells and different types of skeletal muscles in normal lean (+ / +) and severely insulin - resistant, obese - diabetic (ob / ob) mice.