Diet - induced
obese mice given these agonists had reduced adiposity, plasma triglycerides, cholesterol, leptin and IL - 6.
Maratos - Flier's lab hopes to explore whether
obese mice given the hormone will get lean again.
Not exact matches
In the study,
mice were
given food until they became
obese, and were then fed the drug, which increases the cellular metabolism of obesity - linked white fat cells.
BYE BYE BUDS
Mice that became obese on a high - fat diet (right) lost a quarter of their taste buds (stained red) and also had fewer progenitor cells (stained green)-- which give rise to new taste buds — than mice of a healthy weight on a regular diet (le
Mice that became
obese on a high - fat diet (right) lost a quarter of their taste buds (stained red) and also had fewer progenitor cells (stained green)-- which
give rise to new taste buds — than
mice of a healthy weight on a regular diet (le
mice of a healthy weight on a regular diet (left).
(Blaser's group reported earlier this month in Cell that
giving mice penicillin soon after birth changed their gut microbiome and made them much more likely to be
obese as adults.)
«When
given to
obese mouse mothers during pregnancy and lactation, we found it protected their offspring from developing symptoms of liver fat and damage that leads to NAFLD in early adulthood.»
«The goal of our study, which we carried out using a
mouse model of
obese pregnancy, was to determine whether a novel antioxidant
given to mothers during pregnancy and breastfeeding could prevent the development of NAFLD in the offspring.»
In one recent test,
mice implanted with fecal microbes from thin humans stayed thin, while
mice given bacteria from
obese people gained weight.
«But what was really surprising was that when
obese mutant
mice were
given metformin, the most common and inexpensive drug prescribed to Type 2 diabetics, the drug failed to lower their blood sugar levels,» said Steinberg.
The researchers
gave adiponectin intravenously to
obese mice during the last 4 days of their roughly 3 - week - long pregnancies — when the majority of fetal growth occurs.
Even
obese mice bred to stay fat, when
given low - calorie diets, lived longer than
obese mice eating normally.
Giving obese mice a compound in green tea slowed their weight gain, according to Penn State scientists.
The
mice given the Nobiletin flavonoid avoided these issues, while those that did not became
obese, developed type 2 diabetes, and had atherosclerosis and fatty liver issues.
The researchers
gave vitamin D supplements to
obese and non-
obese mice genetically engineered to be predisposed to endometrial cancer.
To explore whether this was a cause of obesity or the effect of it, another research team
gave mice the bacteria from sets of twins where one was
obese and the other was lean.