In addition, administration of a recently discovered adiponectin receptor agonist, AdipoRon, to genetically
obese mice led to improved glucose intolerance and longer lifespans.
Not exact matches
«When given to
obese mouse mothers during pregnancy and lactation, we found it protected their offspring from developing symptoms of liver fat and damage that
leads to NAFLD in early adulthood.»
«When we feed
mice high fat foods, which is like going to McDonalds every day, they become
obese and lose most of their brown fat,» said study
lead author Kosaku Shinoda, a postdoc in Kajimura's lab.
To explore that question, a team
led by Cornell University biomedical engineer Claudia Fischbach first showed that female
mice that were
obese, because of genetics or a high - fat diet, had more fibrous mammary fat pads with straighter collagen fibers than those seen in lean
mice (see image).
The scientists found that
obese mice had more harmful bacteria in their guts compared to lean
mice, which caused inflammation throughout their bodies,
leading to very rapid joint deterioration.
Studies in diet - induced
obese (DIO)
mice with IRAB - A reduced fed blood glucose and insulinemia yet impaired glucose tolerance and
led to protracted insulinemia during a meal challenge.
Because obesity is known to increase a woman's risk of endometrial cancer by 200 percent, a team of researchers
led by oncologist Leena Hilakivi - Clarke of Georgetown Lombardi Comprehensive Cancer Center in Washington, D.C., decided to examine the development of endometrial cancer in
obese mice to that in non-
obese mice.