The current study examined the psychometric properties of the Yale Food Addiction Scale (YFAS) in
obese patients with binge eating disorder (BED) and explored its association with measures of eating disorder and associated psychopathology.
Behavioral weight loss treatment (BWL) and guided self - help based on cognitive behavior therapy (CBTgsh) have both resulted in short - term reductions in binge eating in
obese patients with BED.
Effect of a low - carbohydrate diet on appetite, blood glucose levels, and insulin resistance in
obese patients with type 2 diabetes
Effects on postprandial insulinemia and glycemia in
obese patients with NIDDM
«Alpha - Lipoid acid reduces body weight and regulates triglycerides in
obese patients with diabetes mellitus.»
Another study from 2005 shows that low - carb diets decrease insulin and improve insulin resistance in
obese patients with type 2 diabetes.
In rodents, ketogenic diets reduce reactive oxygen species in the brain34 and reduce central inflammation and reactive oxygen species in a model of multiple sclerosis.35 Two clinical papers have found that ketogenic diet feeding of 12 weeks to 6 months reduced signs of liver inflammation in
obese patients with nonalcoholic fatty liver disease (in addition to improving various other physiological and biochemical variables).36, 37 Unfortunately, basic research into non-alcoholic fatty liver disease has been hampered by species differences between mice and humans in their hepatic reaction to ketogenic diets.38
In one study when researchers in Czechoslovakia treated 60
obese patients with MCT oil they concluded that MCTs offered a number of benefits, stating, «Administration of... medium - chain fatty acids can... improve the long - term success of diet therapy of obese patients.»
Studies of bariatric surgery and weight loss have conclusively shown that type 2 diabetes is reversible and therefore the beta function can be recovered even in massively
obese patients with decades of disease.
Fulghesu et al found that
obese patients with PCOS did not respond to doses under 3 grams / day.
In 2005, in the Annals of Internal Medicine, the article «Effect of a Low - Carbohydrate Diet on Appetite, Blood Glucose Levels, and Insulin Resistance in
Obese Patients with Type 2 Diabetes» showed that 2 weeks of a very low carbohydrate diet with no caloric restrictions reduced appetite and body weight.
A study in the Annals of Internal Medicine found that
obese patients with type - 2 diabetes who went keto for just two weeks improved insulin sensitivity by 75 %.
Another article from 2004 measured changes in cholesterol levels in 83
obese patients with known high cholesterol and high glucose.
Researchers from New Zealand report that morbidity following liver transplant is highest among
obese patients with diabetes, but these risk factors do not influence post-transplant survival.
In addition to Dr. Aminian, study authors of the abstract entitled, «A Nationwide Safety Analysis of Bariatric Surgery in Nonmorbidly
Obese Patients with Type 2 Diabetes,» include John Kirwan, PhD; Bartolome Burguera, MD, PhD; Stacy Brethauer, MD; and Philip Schauer, MD, all from Cleveland Clinic.
Recent studies have shown a similar survival benefit for
obese patients with colorectal or kidney cancer.
Obese patients with metastatic melanoma who are treated with targeted or immune therapies live significantly longer than those with a normal body mass index (BMI), investigators report in a study published in Lancet Oncology of 1,918 patients in six independent clinical cohorts.
«We found that, in
obese patients with asthma, the risk of emergency department visits and hospitalizations for asthma exacerbations decreased by half in the two years after bariatric surgery,» says Kohei Hasegawa, MD, MPH, MGH Department of Emergency Medicine, the lead author of the study.
A study led by Massachusetts General Hospital (MGH) investigators suggests that bariatric surgery can significantly reduce the risk of asthma attacks — also called exacerbations — in
obese patients with asthma.
Using available databases reflecting the utilization of health services in California, Florida and Nebraska — all three of which give access to deidentified information on individual patients — the research team identified 2,261
obese patients with asthma who underwent bariatric surgery from 2007 to 2009 and for whom information covering the two years before and after their surgery was available.
Both groups of animals were equivalent to 55 - to 60 - year - old morbidly
obese patients with uncontrolled diabetes, the most difficult population to treat.
Thus in this study, the authors compared RYGB to an intensive lifestyle and medical intervention (ILMI) for type 2 diabetes, including among only mildly
obese patients with a BMI < 35 kg / m2 (above 30 kg / m2 is considered obese, so 30 - 35 BMI is the least severe obesity category among white people).
The debate will continue in the morbidly
obese patients with BMI over 40, and the super obese with a BMI over 50, regarding what steps can and should be taken to lower the risks before these elective surgical procedures.»
Case in point: I work with a functional med doc who, upon being asked by
an obese patient with metabolic syndrome whether she should drink a can of diet pop or regular pop (because she absolutely had to have just one a day), the doc strongly recommeded the regular pop.
Not exact matches
However, seriously underweight anorexic
patients who see themselves as
obese are not treated
with weight - reducing liposuction by physicians who go along
with their irrational belief.
Obese patients were accordingly advised to replace fats and sweets
with a more prudent dietary pattern characterized by a high intake of fruit, vegetables, whole grains, poultry, and fish (70, 71).
There's good news from UMass Medical School for overweight people
with painfully arthritic hips and knees: A new study finds that
obese patients who underwent knee or hip replacement surgery reported virtually the same pain relief and improved function as normal - weight joint replacement
patients six months after surgery.
Some 15 years ago, during a fellowship at New York Medical College, he observed morbidly
obese patients undergo open bariatric surgery — an old - school Roux - en - Y, done
with giant incisions and often yielding horrendous complications.
When the researchers gave concentrated broccoli sprout extracts to 97 human type 2 diabetes
patients in a 12 - week randomized placebo - controlled trial,
obese participants who entered the study
with dysregulated disease demonstrated significantly decreased fasting blood glucose levels compared to controls.
The same thing happened
with the next three
obese diabetic
patients.
To qualify,
patients must be an acceptable surgical risk and be defined as either severely
obese with a BMI of 40 or greater or have a BMI of 35 or greater
with at least one related condition: diabetes, obstructive sleep apnea, obesity - related cardiomyopathy or heart muscle disease or severe joint disease.
The Northwestern study reported
patients with eczema had 54 percent higher odds of being morbidly
obese, 48 percent higher odds of hypertension, up to 93 percent higher odds of having pre-diabetes and up to 42 percent higher odds of having diabetes.
The review found that 19.3 percent of the
patients diagnosed
with a depressive disorder reported lower back pain, as did 16.75 percent of
patients diagnosed as
obese (a body mass index, or BMI, > 30kg / m ²), 16.53 percent of the
patients diagnosed
with nicotine dependence, and 14.66 percent
with reported alcohol abuse.
The team found that
obese people
with kidney cancer had a 53 % lower risk of dying from renal - cell carcinoma than
patients who were normal weight2.
Egg recipients, however, were of varying body weights, and divided into four groups: lean
with BMI below 20 kg / m2 (1458
patients, 15.2 %), normal
with BMI 20 - 24.9 kg / m2 (5706
patients, 59.5 %), overweight
with BMI 25 - 29.9 kg / m2 (1770
patients, 18.5 %), and
obese with BMI > = 30 kg / m2 (653
patients, 6.8 %).
«Our study emphasizes the importance of individualized therapy strategies and lifestyle interventions in order to prevent structural knee joint degeneration as early as possible in
obese and overweight
patients at risk for osteoarthritis or
with symptomatic osteoarthritis,» Dr. Gersing said.
The results suggest that the risk of revision surgery and most other complications of shoulder arthroplasty increases along
with BMI in
obese patients.
«The question is what underlying mechanism causes this advantage in
obese men, and can we take advantage of it to improve outcomes in
patients with melanoma?»
Weight loss is the commonly recommended strategy for all
obese and overweight
patients with NAFLD.
The treated rodents were not only fatter but also suffered elevated levels of fasting insulin, and alterations in genes related to liver regeneration and detoxification — effects consistent
with metabolic disorders in
obese patients.
Although we often associate fatty liver disease
with obese patients, these results suggest that possible signs of liver disease secondary to NAFLD in lean
patients should be taken very seriously,» said Dr. Angulo.
«The ease
with which this weight loss was achieved in mice — even
with continued caloric binging — is in stark contrast to the Herculean difficulties morbidly
obese patients experience trying to preserve weight loss through dietary restraint,» adds Dr. Gendler.
Concentrations of hs - TnI were compared between 74 morbidly
obese patients who had a type of bariatric surgery called Roux - en - Y gastric bypass, 62 morbidly
obese patients who exercised and restricted their calorie intake, and a control group of 30 people
with normal weight.
The average
patient age was 65.5 years old, and 61 percent of
patients were
obese with a Body Mass Index (BMI) of 33 kg / m ².
«We have an application
with the NIH [National Institutes of Health] to test this in
obese patients that exhibit bingelike behavior.»
The Inventory of Nocturnal Eating, a self - report questionnaire addressing nocturnal eating and sleep disturbance, was administered to out -
patients (N = 126) and in -
patients (N = 24)
with eating disorders,
obese subjects (N = 126) in a trial of an anorexic agent, depressed subjects (N = 207) in an antidepressant trial, and an unselected group (N = 217) of college students.
«While there is no single ideal bariatric procedure that can be applied to all severely
obese patients, we have generally recommended the duodenal switch for those
with a BMI greater than 50,» said study author Vivek Prachand, MD, assistant professor of surgery at the University of Chicago.
As demonstrated by a recent metaanalysis of prospective cohort studies even
obese men and women
with normal cardiometabolic clustering had a 4-fold higher relative risk of developing T2DM, although this risk was only half of that of metabolically unhealthy
obese patients regardless of sex differences in the progression toward T2DM (40).
For
patients with stage II or stage III colon cancer, the difference in long - term survival for leaner
patients compared to those
with a body mass index (BMI) of 35 or greater — which physicians refer to as «very
obese» — was comparable to the difference between those who had surgery followed by chemotherapy and those who had only surgery.
Among men who received treatment for the potentially deadly cancer,
obese patients lived an average of 47 percent longer than those
with a healthy body weight, researchers found.